CA3180143A1 - Procede de production de lymphocytes t autologues genetiquement modifies - Google Patents
Procede de production de lymphocytes t autologues genetiquement modifiesInfo
- Publication number
- CA3180143A1 CA3180143A1 CA3180143A CA3180143A CA3180143A1 CA 3180143 A1 CA3180143 A1 CA 3180143A1 CA 3180143 A CA3180143 A CA 3180143A CA 3180143 A CA3180143 A CA 3180143A CA 3180143 A1 CA3180143 A1 CA 3180143A1
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- cells
- cell
- bioreactor
- soluble
- rocking
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/463—Cellular immunotherapy characterised by recombinant expression
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- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
- A61K39/464411—Immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La présente invention concerne la production de lymphocytes T autologues génétiquement modifiés destinés à être utilisés dans des applications de thérapie cellulaire.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2020/028192 WO2021211104A1 (fr) | 2020-04-15 | 2020-04-15 | Procédé de production de lymphocytes t autologues génétiquement modifiés |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3180143A1 true CA3180143A1 (fr) | 2021-10-21 |
Family
ID=70476574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3180143A Pending CA3180143A1 (fr) | 2020-04-15 | 2020-04-15 | Procede de production de lymphocytes t autologues genetiquement modifies |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4135724A1 (fr) |
| JP (1) | JP2023522642A (fr) |
| AU (1) | AU2020442490A1 (fr) |
| CA (1) | CA3180143A1 (fr) |
| MX (1) | MX2022012990A (fr) |
| WO (1) | WO2021211104A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210324333A1 (en) * | 2020-04-15 | 2021-10-21 | Amgen Inc. | Method for enhancing production of genetically engineered autologous t cells |
| CA3205810A1 (fr) | 2020-12-22 | 2022-06-30 | Amgen Inc. | Recepteurs de lymphocytes t specifiques de mage-b2 |
| AU2022421695A1 (en) | 2021-12-21 | 2024-05-30 | Amgen Inc. | Dcaf4l2-specific t-cell receptors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US7572631B2 (en) * | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| WO2015120096A2 (fr) * | 2014-02-04 | 2015-08-13 | Marc Better | Méthodes de production de lymphocytes t autologues utilisés pour traiter les tumeurs malignes à lymphocytes b et d'autres cancers, et compositions associées |
| GB201509202D0 (en) * | 2015-05-28 | 2015-07-15 | Ge Healthcare Bio Sciences Ab | Semi-static cell culture |
| US20210030793A1 (en) * | 2017-10-26 | 2021-02-04 | St. Jude Children's Research Hospital, Inc. | Methods and compositions for treating cd33+ cancers and improving in vivo persistence of chimeric antigen receptor t cells |
-
2020
- 2020-04-15 EP EP20722966.7A patent/EP4135724A1/fr active Pending
- 2020-04-15 AU AU2020442490A patent/AU2020442490A1/en active Pending
- 2020-04-15 WO PCT/US2020/028192 patent/WO2021211104A1/fr unknown
- 2020-04-15 MX MX2022012990A patent/MX2022012990A/es unknown
- 2020-04-15 JP JP2022562462A patent/JP2023522642A/ja active Pending
- 2020-04-15 CA CA3180143A patent/CA3180143A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021211104A1 (fr) | 2021-10-21 |
| MX2022012990A (es) | 2023-01-11 |
| JP2023522642A (ja) | 2023-05-31 |
| EP4135724A1 (fr) | 2023-02-22 |
| AU2020442490A1 (en) | 2022-11-17 |
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