CA3152021A1 - Substituted (7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino compounds useful as jak1 inhibitors - Google Patents
Substituted (7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino compounds useful as jak1 inhibitors Download PDFInfo
- Publication number
- CA3152021A1 CA3152021A1 CA3152021A CA3152021A CA3152021A1 CA 3152021 A1 CA3152021 A1 CA 3152021A1 CA 3152021 A CA3152021 A CA 3152021A CA 3152021 A CA3152021 A CA 3152021A CA 3152021 A1 CA3152021 A1 CA 3152021A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- salt
- formula
- jak1
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962891706P | 2019-08-26 | 2019-08-26 | |
| US62/891,706 | 2019-08-26 | ||
| PCT/US2020/047767 WO2021041392A1 (en) | 2019-08-26 | 2020-08-25 | Substituted (7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino compounds useful as jak1 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3152021A1 true CA3152021A1 (en) | 2021-03-04 |
Family
ID=74685810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3152021A Pending CA3152021A1 (en) | 2019-08-26 | 2020-08-25 | Substituted (7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino compounds useful as jak1 inhibitors |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12492204B2 (enExample) |
| EP (1) | EP4021452B1 (enExample) |
| JP (1) | JP7671738B2 (enExample) |
| CN (1) | CN114761011B (enExample) |
| AU (1) | AU2020338043B2 (enExample) |
| CA (1) | CA3152021A1 (enExample) |
| ES (1) | ES2974946T3 (enExample) |
| PL (1) | PL4021452T3 (enExample) |
| WO (1) | WO2021041392A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12492204B2 (en) * | 2019-08-26 | 2025-12-09 | Chemwerth, Inc. | Substituted (7H-pyrrolo[2,3-D]pyrimidin-4-yl) amino compounds useful as JAK 1 inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009241469B2 (en) * | 2008-04-30 | 2015-05-07 | National Health Research Institutes | Fused bicyclic pyrimidine compounds as Aurora kinase inhibitors |
| AU2010308028A1 (en) | 2009-10-15 | 2012-04-19 | Pfizer Inc. | Pyrrolo[2,3-d] pyrimidine compounds |
| JP6075736B2 (ja) * | 2011-12-21 | 2017-02-08 | ジエンス ヘンルイ メデイシンカンパニー リミテッドＪｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．，Ｌｔｄ． | ピロール−６員ヘテロアリール環誘導体、その合成法およびその医薬用途 |
| RU2699034C1 (ru) * | 2016-02-16 | 2019-09-03 | ЗОИТИС СЕРВИСЕЗ ЭлЭлСи | Способ получения соединений 7H-пирроло[2,3-d]пиримидина |
| JP6944496B2 (ja) * | 2018-10-22 | 2021-10-06 | ファイザー・インク | ピロロ［２，３−ｄ］ピリミジントシル酸塩、その結晶形態、ならびにその製造方法および中間体 |
| US12492204B2 (en) * | 2019-08-26 | 2025-12-09 | Chemwerth, Inc. | Substituted (7H-pyrrolo[2,3-D]pyrimidin-4-yl) amino compounds useful as JAK 1 inhibitors |
-
2020
- 2020-08-25 US US17/638,074 patent/US12492204B2/en active Active
- 2020-08-25 CN CN202080074639.8A patent/CN114761011B/zh active Active
- 2020-08-25 ES ES20858240T patent/ES2974946T3/es active Active
- 2020-08-25 PL PL20858240.3T patent/PL4021452T3/pl unknown
- 2020-08-25 CA CA3152021A patent/CA3152021A1/en active Pending
- 2020-08-25 WO PCT/US2020/047767 patent/WO2021041392A1/en not_active Ceased
- 2020-08-25 AU AU2020338043A patent/AU2020338043B2/en active Active
- 2020-08-25 JP JP2022513571A patent/JP7671738B2/ja active Active
- 2020-08-25 EP EP20858240.3A patent/EP4021452B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022545836A (ja) | 2022-10-31 |
| CN114761011B (zh) | 2024-06-14 |
| EP4021452A1 (en) | 2022-07-06 |
| US20220274992A1 (en) | 2022-09-01 |
| US12492204B2 (en) | 2025-12-09 |
| JP7671738B2 (ja) | 2025-05-02 |
| EP4021452A4 (en) | 2023-01-04 |
| AU2020338043A1 (en) | 2022-03-31 |
| WO2021041392A1 (en) | 2021-03-04 |
| PL4021452T3 (pl) | 2024-05-06 |
| EP4021452B1 (en) | 2023-12-20 |
| AU2020338043B2 (en) | 2025-12-18 |
| CN114761011A (zh) | 2022-07-15 |
| ES2974946T3 (es) | 2024-07-02 |
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