CA3137365A1 - Formulations et anticorps anti-cd38 - Google Patents
Formulations et anticorps anti-cd38 Download PDFInfo
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- CA3137365A1 CA3137365A1 CA3137365A CA3137365A CA3137365A1 CA 3137365 A1 CA3137365 A1 CA 3137365A1 CA 3137365 A CA3137365 A CA 3137365A CA 3137365 A CA3137365 A CA 3137365A CA 3137365 A1 CA3137365 A1 CA 3137365A1
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A61P35/00—Antineoplastic agents
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention concerne des anticorps qui se lient spécifiquement au CD38 humain, des formulations et des formes posologiques unitaires comprenant les anticorps, des procédés de préparation de ces anticorps et des procédés d'utilisation de ces anticorps.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962837518P | 2019-04-23 | 2019-04-23 | |
US62/837,518 | 2019-04-23 | ||
US201962859699P | 2019-06-10 | 2019-06-10 | |
US62/859,699 | 2019-06-10 | ||
EP20305145 | 2020-02-17 | ||
EP20305145.3 | 2020-02-17 | ||
EP20305146.1 | 2020-02-17 | ||
EP20305146 | 2020-02-17 | ||
PCT/US2020/029531 WO2020219681A1 (fr) | 2019-04-23 | 2020-04-23 | Formulations et anticorps anti-cd38 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3137365A1 true CA3137365A1 (fr) | 2020-10-29 |
Family
ID=70739160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3137365A Pending CA3137365A1 (fr) | 2019-04-23 | 2020-04-23 | Formulations et anticorps anti-cd38 |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP3958898A1 (fr) |
JP (1) | JP2022529502A (fr) |
KR (1) | KR20220003562A (fr) |
CN (1) | CN114269375A (fr) |
AU (1) | AU2020261039A1 (fr) |
BR (1) | BR112021021060A2 (fr) |
CA (1) | CA3137365A1 (fr) |
CO (1) | CO2021015462A2 (fr) |
IL (1) | IL287477A (fr) |
MA (1) | MA55761A (fr) |
MX (1) | MX2021012967A (fr) |
SG (1) | SG11202111602YA (fr) |
TW (1) | TW202104269A (fr) |
WO (1) | WO2020219681A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024023843A1 (fr) * | 2022-07-26 | 2024-02-01 | Dr. Reddy’S Laboratories Limited | Formulation pharmaceutique d'un anticorps thérapeutique et ses préparations |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3052445C (fr) | 2004-07-10 | 2023-08-22 | Kerry S. Campbell | Lignees de cellules tueuses, naturelles, humaines et genetiquement modifiees |
EP1914242A1 (fr) * | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Nouveau anticorps Anti-CD38 pour le traitement du cancer |
KR102096224B1 (ko) * | 2011-10-28 | 2020-04-03 | 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 | 폴리펩티드 구축물 및 이의 용도 |
AU2016350717B2 (en) * | 2015-11-03 | 2023-08-10 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
CN108752475B (zh) * | 2018-06-14 | 2021-07-30 | 北京智仁美博生物科技有限公司 | 抗人cd38抗体及其用途 |
-
2020
- 2020-04-23 MX MX2021012967A patent/MX2021012967A/es unknown
- 2020-04-23 EP EP20726267.6A patent/EP3958898A1/fr active Pending
- 2020-04-23 WO PCT/US2020/029531 patent/WO2020219681A1/fr unknown
- 2020-04-23 CN CN202080030148.3A patent/CN114269375A/zh active Pending
- 2020-04-23 KR KR1020217037641A patent/KR20220003562A/ko unknown
- 2020-04-23 JP JP2021562989A patent/JP2022529502A/ja active Pending
- 2020-04-23 BR BR112021021060A patent/BR112021021060A2/pt unknown
- 2020-04-23 SG SG11202111602YA patent/SG11202111602YA/en unknown
- 2020-04-23 AU AU2020261039A patent/AU2020261039A1/en active Pending
- 2020-04-23 MA MA055761A patent/MA55761A/fr unknown
- 2020-04-23 TW TW109113639A patent/TW202104269A/zh unknown
- 2020-04-23 CA CA3137365A patent/CA3137365A1/fr active Pending
-
2021
- 2021-10-21 IL IL287477A patent/IL287477A/en unknown
- 2021-11-17 CO CONC2021/0015462A patent/CO2021015462A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
SG11202111602YA (en) | 2021-11-29 |
CO2021015462A2 (es) | 2021-12-10 |
WO2020219681A1 (fr) | 2020-10-29 |
MA55761A (fr) | 2022-03-02 |
CN114269375A (zh) | 2022-04-01 |
IL287477A (en) | 2021-12-01 |
BR112021021060A2 (pt) | 2021-12-14 |
TW202104269A (zh) | 2021-02-01 |
EP3958898A1 (fr) | 2022-03-02 |
JP2022529502A (ja) | 2022-06-22 |
MX2021012967A (es) | 2022-01-18 |
KR20220003562A (ko) | 2022-01-10 |
AU2020261039A1 (en) | 2021-12-09 |
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