CA3131298A1 - Triterpenoid antifungals for the treatment or prevention of pneumocystis spp. pneumonia - Google Patents
Triterpenoid antifungals for the treatment or prevention of pneumocystis spp. pneumonia Download PDFInfo
- Publication number
- CA3131298A1 CA3131298A1 CA3131298A CA3131298A CA3131298A1 CA 3131298 A1 CA3131298 A1 CA 3131298A1 CA 3131298 A CA3131298 A CA 3131298A CA 3131298 A CA3131298 A CA 3131298A CA 3131298 A1 CA3131298 A1 CA 3131298A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- hydrate
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962811456P | 2019-02-27 | 2019-02-27 | |
| US62/811,456 | 2019-02-27 | ||
| PCT/US2020/019724 WO2020176527A1 (en) | 2019-02-27 | 2020-02-25 | Triterpenoid antifungals for the treatment or prevention of pneumocystis spp. pneumonia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3131298A1 true CA3131298A1 (en) | 2020-09-03 |
Family
ID=70005768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3131298A Pending CA3131298A1 (en) | 2019-02-27 | 2020-02-25 | Triterpenoid antifungals for the treatment or prevention of pneumocystis spp. pneumonia |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12594266B2 (https=) |
| EP (1) | EP3930716B1 (https=) |
| JP (1) | JP7581219B2 (https=) |
| KR (1) | KR20210133241A (https=) |
| CN (1) | CN113631165A (https=) |
| AU (1) | AU2020228036B2 (https=) |
| BR (1) | BR112021016876A2 (https=) |
| CA (1) | CA3131298A1 (https=) |
| EA (1) | EA202192344A1 (https=) |
| ES (1) | ES3055272T3 (https=) |
| IL (1) | IL285839A (https=) |
| MA (1) | MA55081A (https=) |
| MX (2) | MX2021010311A (https=) |
| TW (1) | TWI910099B (https=) |
| WO (1) | WO2020176527A1 (https=) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166135A (en) * | 1988-09-12 | 1992-11-24 | Merck & Company, Inc. | Method for the control of pneumocystis carinii |
| DK173802B1 (da) * | 1988-09-12 | 2001-11-05 | Merck & Co Inc | Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner |
| US5756472A (en) | 1996-01-31 | 1998-05-26 | Merck & Co., Inc. | Antifungal agent obtained from hormonema |
| JP5245057B2 (ja) | 2006-04-03 | 2013-07-24 | メルク・シャープ・アンド・ドーム・コーポレーション | 抗真菌剤 |
| WO2010019204A1 (en) | 2008-08-12 | 2010-02-18 | Merck Sharp & Dohme Corp. | Antifungal agents |
| CN108883152A (zh) * | 2016-01-08 | 2018-11-23 | 奇达拉治疗公司 | 防止和治疗肺孢子虫感染的方法 |
| MA49889A (fr) * | 2017-04-10 | 2020-06-24 | Scynexis Inc | Agents antifongiques utilisés en association |
| KR102807716B1 (ko) * | 2017-08-04 | 2025-05-13 | 싸이넥시스, 인크. | 산성 pH에서 증진된 활성을 갖는 항진균제 |
-
2020
- 2020-02-25 BR BR112021016876A patent/BR112021016876A2/pt unknown
- 2020-02-25 JP JP2021549801A patent/JP7581219B2/ja active Active
- 2020-02-25 AU AU2020228036A patent/AU2020228036B2/en active Active
- 2020-02-25 WO PCT/US2020/019724 patent/WO2020176527A1/en not_active Ceased
- 2020-02-25 US US17/432,926 patent/US12594266B2/en active Active
- 2020-02-25 CA CA3131298A patent/CA3131298A1/en active Pending
- 2020-02-25 KR KR1020217030157A patent/KR20210133241A/ko active Pending
- 2020-02-25 MX MX2021010311A patent/MX2021010311A/es unknown
- 2020-02-25 EA EA202192344A patent/EA202192344A1/ru unknown
- 2020-02-25 EP EP20714386.8A patent/EP3930716B1/en active Active
- 2020-02-25 ES ES20714386T patent/ES3055272T3/es active Active
- 2020-02-25 CN CN202080023125.XA patent/CN113631165A/zh active Pending
- 2020-02-25 MA MA055081A patent/MA55081A/fr unknown
- 2020-02-27 TW TW109106501A patent/TWI910099B/zh active
-
2021
- 2021-08-24 IL IL285839A patent/IL285839A/en unknown
- 2021-08-26 MX MX2025004197A patent/MX2025004197A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2021010311A (es) | 2022-01-04 |
| JP2022523212A (ja) | 2022-04-21 |
| KR20210133241A (ko) | 2021-11-05 |
| WO2020176527A1 (en) | 2020-09-03 |
| US12594266B2 (en) | 2026-04-07 |
| AU2020228036A1 (en) | 2021-09-23 |
| TWI910099B (zh) | 2026-01-01 |
| MA55081A (fr) | 2022-01-05 |
| JP7581219B2 (ja) | 2024-11-12 |
| AU2020228036B2 (en) | 2025-08-07 |
| EP3930716B1 (en) | 2025-09-10 |
| IL285839A (en) | 2021-10-31 |
| EP3930716A1 (en) | 2022-01-05 |
| CN113631165A (zh) | 2021-11-09 |
| BR112021016876A2 (pt) | 2021-11-03 |
| MX2025004197A (es) | 2025-09-02 |
| ES3055272T3 (en) | 2026-02-10 |
| TW202045169A (zh) | 2020-12-16 |
| US20230149376A1 (en) | 2023-05-18 |
| EA202192344A1 (ru) | 2021-11-15 |
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| HK40066679B (en) | Triterpenoid antifungals for the treatment of pneumocystis spp. pneumonia | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20240223 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - STANDARD Year of fee payment: 5 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250206 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20250206 Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250206 |
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| D15 | Examination report completed |
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| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20250618 |
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| W00 | Other event occurred |
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| P13 | Application amended |
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| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 6TH ANNIV.) - STANDARD Year of fee payment: 6 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20260223 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20260223 |
|
| D15 | Examination report completed |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT Effective date: 20260331 |