CA3130135A1 - Enzymes with ruvc domains - Google Patents
Enzymes with ruvc domains Download PDFInfo
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- CA3130135A1 CA3130135A1 CA3130135A CA3130135A CA3130135A1 CA 3130135 A1 CA3130135 A1 CA 3130135A1 CA 3130135 A CA3130135 A CA 3130135A CA 3130135 A CA3130135 A CA 3130135A CA 3130135 A1 CA3130135 A1 CA 3130135A1
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- seq
- sequence
- endonuclease
- nos
- nuclease system
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
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| PCT/US2020/018432 WO2020168291A1 (en) | 2019-02-14 | 2020-02-14 | Enzymes with ruvc domains |
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| CA3130135A1 (en) | 2019-02-14 | 2020-08-20 | Metagenomi Ip Technologies, Llc | Enzymes with ruvc domains |
| US10913941B2 (en) | 2019-02-14 | 2021-02-09 | Metagenomi Ip Technologies, Llc | Enzymes with RuvC domains |
| GB2594339B (en) * | 2020-02-14 | 2023-02-08 | Metagenomi Inc | Enzymes with RUVC domains |
| EP4114932A4 (en) | 2020-03-06 | 2024-03-13 | Metagenomi, Inc. | CLASS II, TYPE V CRISPR SYSTEMS |
| MX2022012110A (es) * | 2020-03-31 | 2022-10-18 | Metagenomi Inc | Sistemas crispr clase ii tipo ii. |
| WO2022056301A1 (en) * | 2020-09-11 | 2022-03-17 | Metagenomi Ip Technologies, Llc | Base editing enzymes |
| WO2022098681A2 (en) * | 2020-11-03 | 2022-05-12 | Caspr Biotech Corporation | Novel class 2 crispr-cas rna-guided endonucleases |
| KR20230134543A (ko) * | 2021-01-22 | 2023-09-21 | 메타지노미, 인크. | 신규한 조작된 뉴클레아제 및 키메라 뉴클레아제 |
| WO2022159742A1 (en) * | 2021-01-22 | 2022-07-28 | Metagenomi, Inc | Novel engineered and chimeric nucleases |
| WO2022232638A2 (en) * | 2021-04-30 | 2022-11-03 | Metagenomi, Inc. | Enzymes with ruvc domains |
| WO2023122663A2 (en) * | 2021-12-23 | 2023-06-29 | Mammoth Biosciences, Inc. | Effector proteins and methods of use |
| WO2023194359A1 (en) * | 2022-04-04 | 2023-10-12 | Alia Therapeutics Srl | Compositions and methods for treatment of usher syndrome type 2a |
| WO2023245141A2 (en) * | 2022-06-15 | 2023-12-21 | Beam Therapeutics Inc. | Compositions and methods for reducing complement activation |
| WO2024056880A2 (en) * | 2022-09-16 | 2024-03-21 | Alia Therapeutics Srl | Enqp type ii cas proteins and applications thereof |
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| US10392607B2 (en) * | 2015-06-03 | 2019-08-27 | The Regents Of The University Of California | Cas9 variants and methods of use thereof |
| WO2016205759A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation |
| WO2018035250A1 (en) * | 2016-08-17 | 2018-02-22 | The Broad Institute, Inc. | Methods for identifying class 2 crispr-cas systems |
| CN112020554A (zh) * | 2018-02-23 | 2020-12-01 | 先锋国际良种公司 | 新颖cas9直系同源物 |
| CA3130135A1 (en) | 2019-02-14 | 2020-08-20 | Metagenomi Ip Technologies, Llc | Enzymes with ruvc domains |
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| JP7502537B2 (ja) | 2024-06-18 |
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