CA3128153A1 - Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein - Google Patents

Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein Download PDF

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Publication number
CA3128153A1
CA3128153A1 CA3128153A CA3128153A CA3128153A1 CA 3128153 A1 CA3128153 A1 CA 3128153A1 CA 3128153 A CA3128153 A CA 3128153A CA 3128153 A CA3128153 A CA 3128153A CA 3128153 A1 CA3128153 A1 CA 3128153A1
Authority
CA
Canada
Prior art keywords
hydroxyvitamin
patient
serum
treatment
shpt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3128153A
Other languages
English (en)
French (fr)
Inventor
Charles W. Bishop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eirgen Pharma Ltd
Original Assignee
Eirgen Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eirgen Pharma Ltd filed Critical Eirgen Pharma Ltd
Publication of CA3128153A1 publication Critical patent/CA3128153A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
CA3128153A 2019-02-06 2020-02-06 Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein Pending CA3128153A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962802148P 2019-02-06 2019-02-06
US62/802,148 2019-02-06
PCT/IB2020/000089 WO2020161543A1 (en) 2019-02-06 2020-02-06 Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein

Publications (1)

Publication Number Publication Date
CA3128153A1 true CA3128153A1 (en) 2020-08-13

Family

ID=69903711

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3128153A Pending CA3128153A1 (en) 2019-02-06 2020-02-06 Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein

Country Status (9)

Country Link
US (1) US20220226351A1 (enExample)
EP (1) EP3920938A1 (enExample)
JP (2) JP2022519789A (enExample)
KR (1) KR20210126023A (enExample)
CN (1) CN113573714A (enExample)
AU (2) AU2020218639A1 (enExample)
CA (1) CA3128153A1 (enExample)
MX (1) MX2020011741A (enExample)
WO (1) WO2020161543A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025094144A1 (en) 2023-11-02 2025-05-08 Eirgen Pharma Ltd. Controlling loss of kidney function

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2640094C (en) 2006-02-03 2015-04-14 Proventiv Therapeutics, Llc Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
PL2679228T3 (pl) 2006-06-21 2018-07-31 Opko Ireland Global Holdings, Ltd. Terapia z użyciem środka do uzupełniania witaminy D i środka do zastępowania hormonami witaminy D
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
SI2481400T1 (sl) * 2007-04-25 2014-11-28 Opko IP Holdings II, Inc. Nadzorovano oralno sproščanje sestavkov, ki vsebujejo spojino vitamina D in voskasti nosilec
FI3225243T3 (fi) 2007-04-25 2025-10-13 Opko Renal Llc Menetelmä sekundaarisen hyperparatyreoosin turvalliseen ja tehokkaaseen hoitoon ja ehkäisyyn kroonisen munuaistaudin yhteydessä
EP3112476B1 (en) 2008-04-02 2023-08-02 EirGen Pharma Ltd. Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders
AU2013203489B2 (en) * 2008-07-24 2015-02-05 Wisconsin Alumni Research Foundation Once-a-week administration of 25-hydroxy vitamin D3 to sustain elevated steady-state pharmacokinetic blood concentration
EP3636280B1 (en) * 2010-03-29 2025-05-14 EirGen Pharma Ltd. Methods and compositions for reducing parathyroid levels
KR101847947B1 (ko) * 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) * 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
SG10201913863TA (en) * 2016-03-28 2020-03-30 Opko Ireland Global Holdings Limited Methods of vitamin d treatment
JP7590184B2 (ja) * 2018-04-03 2024-11-26 オプコ アイルランド グローバル ホールディングス リミテッド 肥満外科手術患者におけるカルシフェジオールの使用

Also Published As

Publication number Publication date
WO2020161543A1 (en) 2020-08-13
CN113573714A (zh) 2021-10-29
EP3920938A1 (en) 2021-12-15
JP2022519789A (ja) 2022-03-24
KR20210126023A (ko) 2021-10-19
MX2020011741A (es) 2021-03-02
US20220226351A1 (en) 2022-07-21
JP2025031720A (ja) 2025-03-07
AU2020218639A1 (en) 2021-08-12
AU2025259887A1 (en) 2025-11-20

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Effective date: 20240202