CA3108835A1 - Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease - Google Patents

Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease Download PDF

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Publication number
CA3108835A1
CA3108835A1 CA3108835A CA3108835A CA3108835A1 CA 3108835 A1 CA3108835 A1 CA 3108835A1 CA 3108835 A CA3108835 A CA 3108835A CA 3108835 A CA3108835 A CA 3108835A CA 3108835 A1 CA3108835 A1 CA 3108835A1
Authority
CA
Canada
Prior art keywords
patient
proadm
level
sample
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3108835A
Other languages
English (en)
French (fr)
Inventor
Darius Wilson
Jesus Francisco Bermejo Martin
Luis Garcia Ortiz
Carmen Herrero Rodriguez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRAHMS GmbH
Fundacion Instituto De Estudios De Ciencias de la Salud De Castilla Y Leon
Original Assignee
BRAHMS GmbH
Instituto de Investigacion Biomedica de Salamanca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BRAHMS GmbH, Instituto de Investigacion Biomedica de Salamanca filed Critical BRAHMS GmbH
Publication of CA3108835A1 publication Critical patent/CA3108835A1/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA3108835A 2018-08-08 2019-08-08 Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease Pending CA3108835A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18188098.0 2018-08-08
EP18188098 2018-08-08
EP18200907.6A EP3608673A1 (en) 2018-08-08 2018-10-17 Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease
EP18200907.6 2018-10-17
PCT/EP2019/071334 WO2020030745A1 (en) 2018-08-08 2019-08-08 Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease

Publications (1)

Publication Number Publication Date
CA3108835A1 true CA3108835A1 (en) 2020-02-13

Family

ID=63207559

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3108835A Pending CA3108835A1 (en) 2018-08-08 2019-08-08 Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease

Country Status (7)

Country Link
US (1) US20210293830A1 (https=)
EP (2) EP3608673A1 (https=)
JP (2) JP7402858B2 (https=)
CN (1) CN113056675A (https=)
BR (1) BR112021002281A2 (https=)
CA (1) CA3108835A1 (https=)
WO (1) WO2020030745A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210285949A1 (en) * 2020-03-16 2021-09-16 Sphingotec Gmbh Pro-adrenomedullin or fragment thereof in patients infected with corona virus and treatments with binder against adrenomedullin
EP4133274A1 (en) * 2020-04-06 2023-02-15 B.R.A.H.M.S GmbH Pro-adrenomedullin for prognosing disease progression in severe acute respiratory syndrome (sars)
CN116525105B (zh) * 2023-06-29 2023-10-03 中国人民解放军总医院 一种心源性休克预后预测预警系统、设备及可存储介质

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570703B1 (fr) 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4882733A (en) 1987-03-13 1989-11-21 Ford Aerospace Corporation Method and apparatus for combining encoding and modulation
FR2664699B1 (fr) 1990-07-13 1995-08-18 Cis Bio Int Procede d'amplification du signal d'emission d'un compose luminescent.
DE10316583A1 (de) * 2003-04-10 2004-10-28 B.R.A.H.M.S Aktiengesellschaft Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung
ES2300681T3 (es) * 2004-07-22 2008-06-16 Brahms Aktiengesellschaft Procedimiento para el diagnostico y tratamiento de pacientes criticos con endotelina, agonistas de endotelina y antagonistas de adrenomedulina.
JP5711131B2 (ja) * 2008-10-07 2015-04-30 ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング 最初の有害事象の予測のためのバイオマーカー
EP2438447B1 (en) * 2009-06-05 2015-02-18 B.R.A.H.M.S GmbH Detection of bacterial infections in subjects suffering from dyspnea.
WO2012059477A1 (en) * 2010-11-01 2012-05-10 B.R.A.H.M.S Gmbh Prognosis and risk assessment of patients with non-specific complaints
DK2780717T3 (en) * 2011-11-16 2017-02-13 Sphingotec Gmbh ADRENOMEDULLINASSAYS AND METHODS FOR DETERMINING MODERN ADRENOMEDULLIN
US20180348235A1 (en) * 2015-11-27 2018-12-06 B.R.A.H.M.S Gmbh MR-proADM as marker for the extracellular volume status of a subject
EP4231018A3 (en) * 2016-07-08 2023-11-15 SphingoTec GmbH Adrenomedullin for assessing congestion in a subject with acute heart failure
RU2764766C2 (ru) * 2016-08-09 2022-01-21 Б.Р.А.Х.М.С. Гмбх Гистоны и/или proadm в качестве маркеров, свидетельствующих об органной дисфункции
CA3033094A1 (en) * 2016-08-09 2018-02-15 B.R.A.H.M.S Gmbh Histones and/or proadm as markers indicating an adverse event

Also Published As

Publication number Publication date
JP2021534385A (ja) 2021-12-09
CN113056675A (zh) 2021-06-29
JP7402858B2 (ja) 2023-12-21
US20210293830A1 (en) 2021-09-23
JP2024023615A (ja) 2024-02-21
EP3608673A1 (en) 2020-02-12
EP3833979A1 (en) 2021-06-16
BR112021002281A2 (pt) 2021-05-04
WO2020030745A1 (en) 2020-02-13

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