CA3108236A1 - Methods and compositions for inhibition of egf/egfr pathway in combination with anaplastic lymphoma kinase inhibitors - Google Patents
Methods and compositions for inhibition of egf/egfr pathway in combination with anaplastic lymphoma kinase inhibitors Download PDFInfo
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- CA3108236A1 CA3108236A1 CA3108236A CA3108236A CA3108236A1 CA 3108236 A1 CA3108236 A1 CA 3108236A1 CA 3108236 A CA3108236 A CA 3108236A CA 3108236 A CA3108236 A CA 3108236A CA 3108236 A1 CA3108236 A1 CA 3108236A1
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| US201862760529P | 2018-11-13 | 2018-11-13 | |
| US62/760,529 | 2018-11-13 | ||
| US201962822290P | 2019-03-22 | 2019-03-22 | |
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| PCT/IB2019/000905 WO2020030977A2 (en) | 2018-08-07 | 2019-08-07 | Methods and compositions for inhibition of egf/egfr pathway in cobination with anaplastic lymphoma kinase inhibitors |
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| CN112300284B (zh) * | 2020-12-29 | 2021-04-06 | 慈达(广州)生物技术有限公司 | 核酸筛选结合抗体检测用于癌症检测中的用途及其制备的试剂盒 |
| WO2022256360A1 (en) * | 2021-06-02 | 2022-12-08 | Neuvogen, Inc. | Tumor cell vaccines |
| WO2023059801A1 (en) * | 2021-10-06 | 2023-04-13 | The Regents Of The University Of Colorado, A Body Corporate | Biomarkers for egfr-mediated resistance in oncogene-driven cancers and methods of treating, preventing, and/or ameliorating oncogene-driven cancers |
| KR102685187B1 (ko) | 2021-10-15 | 2024-07-16 | 제이투에이치바이오텍 (주) | Alk 및/또는 egfr 돌연변이 키나제 억제 효과를 나타내는 화합물 및 이의 의약 용도 |
| CA3236522A1 (en) * | 2021-10-28 | 2023-05-04 | In3Bio Ltd. | Methods of using anti-egf antibodies to augment the activity of braf and kras inhibitors |
| TW202339767A (zh) * | 2022-01-18 | 2023-10-16 | 大陸商齊魯製藥有限公司 | 螺環芳基磷氧化物與抗ｅｇｆｒ抗體的聯用藥物組合物及其用途 |
| WO2024017352A1 (zh) * | 2022-07-22 | 2024-01-25 | 四川大学 | 用于rdaa阳性疾病的诊断和治疗的方法和试剂盒 |
| WO2024249331A1 (en) * | 2023-05-26 | 2024-12-05 | The Board Of Regents Of The University Of Texas System | Combined rtk and alk inhibition in rtk driven cancers |
| KR20250120789A (ko) | 2024-02-02 | 2025-08-11 | 제이투에이치바이오텍 (주) | E3 리가제 리간드 화합물, alk 및/또는 egfr 돌연변이 키나제 억제 효과를 나타내는 화합물 및 이의 의약 용도 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPH10147952A (ja) | 1996-11-18 | 1998-06-02 | Komatsu Ltd | ブルドーザのドージング装置 |
| US8828391B2 (en) * | 2011-05-17 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Method for EGFR directed combination treatment of non-small cell lung cancer |
| KR20140064971A (ko) * | 2011-09-19 | 2014-05-28 | 제넨테크, 인크. | c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료 |
| MX347772B (es) | 2012-03-06 | 2017-05-12 | Cephalon Inc | Derivado de 2,4-diaminopirimidina biciclico fusionado como un inhibidor dual de alk y fak. |
| US20150218652A1 (en) * | 2012-08-31 | 2015-08-06 | The Regents Of The Unversity Of Colorado, A Body Corporate | Methods for diagnosis and treatment of cancer |
| US20160017431A1 (en) * | 2014-03-28 | 2016-01-21 | Driver Group | Methods for Predicting EGFR Tyrosine Kinase Inhibitor Efficacy |
| CA2946538A1 (en) * | 2014-04-04 | 2015-10-08 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
| US20160333087A1 (en) * | 2015-05-12 | 2016-11-17 | Bioven 3 Limited | Methods and compositions for inhibition of egf/egfr pathway in combination with tyrosine kinase inhibitors |
| EP3303399A1 (en) * | 2015-06-08 | 2018-04-11 | H. Hoffnabb-La Roche Ag | Methods of treating cancer using anti-ox40 antibodies |
| KR20180025888A (ko) * | 2015-06-08 | 2018-03-09 | 제넨테크, 인크. | 항-ox40 항체 및 pd-1 축 결합 길항제를 사용하여 암을 치료하는 방법 |
| JP7751357B2 (ja) | 2017-07-18 | 2025-10-08 | イン３バイオ・リミテッド | 合成タンパク質およびその治療学的用途 |
| RU2654695C1 (ru) | 2017-07-28 | 2018-05-22 | Акционерное Общество "Р-Фарм" (Ао "Р-Фарм") | 8-(1-{ 4-{ (5-Хлор-4-{ (2-(диметилфосфорил)фенил)амино} пиримидин-2-ил)амино)-3-метоксифенил} пиперидин-4-ил)-1-метил-1,8-диазаспиро(4.5)декан-2-он и его фармацевтически приемлемые соли в качестве модулятора ALK и EGER, предназначенные для лечения рака |
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| JP2021534094A (ja) | 2021-12-09 |
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| CN112996534B (zh) | 2025-11-18 |
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