CA3093428A1 - Compositions topiques de soins de la peau - Google Patents

Compositions topiques de soins de la peau Download PDF

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Publication number
CA3093428A1
CA3093428A1 CA3093428A CA3093428A CA3093428A1 CA 3093428 A1 CA3093428 A1 CA 3093428A1 CA 3093428 A CA3093428 A CA 3093428A CA 3093428 A CA3093428 A CA 3093428A CA 3093428 A1 CA3093428 A1 CA 3093428A1
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CA
Canada
Prior art keywords
composition
skin
composition according
skin care
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA3093428A
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English (en)
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CA3093428C (fr
Inventor
Nat Adkins, Jr.
Troy Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ocusoft Inc
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Ocusoft Inc
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Publication of CA3093428A1 publication Critical patent/CA3093428A1/fr
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Publication of CA3093428C publication Critical patent/CA3093428C/fr
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des compositions et des méthodes de traitement de rougeurs de la peau. Selon un mode de réalisation, l'invention concerne une composition topique de soin de la peau ayant un véhicule dermatologiquement acceptable, tel que de l'eau et une pluralité d'ingrédients dissous dans le véhicule. Les ingrédients comprennent : un mélange d'huiles naturelles; une pluralité de vitamines; et 0,1 à 1 % en poids de phytosphingosine de salicyloyle. La composition est inappropriée pour une application sur les paupières ou le contour des yeux. Le mélange d'huiles naturelles comprend : un extrait de jus de feuilles d'aloe barbadensis; cocos nucifera (huile de noix de coco); des glycosaminoglycanes hydrolysés; et des triglycérides capryliques/capriques. La pluralité de vitamines est choisie dans un groupe constitué de vitamine C, de vitamine E, de sels/dérivés de vitamine C et de vitamine E, et de mélanges de ceux-ci. Dans un aspect, la pluralité de vitamines comprend : du phosphate d'ascorbyle de sodium; du phosphate de tocophérol de lauriminodipropionate de disodium; et de l'huile de jojoba.
CA3093428A 2018-03-09 2019-03-07 Compositions topiques de soins de la peau Active CA3093428C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862640848P 2018-03-09 2018-03-09
US62/640,848 2018-03-09
PCT/US2019/021142 WO2019173584A1 (fr) 2018-03-09 2019-03-07 Compositions topiques de soins de la peau

Publications (2)

Publication Number Publication Date
CA3093428A1 true CA3093428A1 (fr) 2019-09-12
CA3093428C CA3093428C (fr) 2023-07-11

Family

ID=67842864

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3093428A Active CA3093428C (fr) 2018-03-09 2019-03-07 Compositions topiques de soins de la peau

Country Status (15)

Country Link
US (2) US10576048B2 (fr)
EP (1) EP3761952B1 (fr)
JP (2) JP2021515021A (fr)
KR (1) KR20200131850A (fr)
CN (1) CN111836614A (fr)
AR (1) AR114376A1 (fr)
AU (1) AU2019230097B2 (fr)
CA (1) CA3093428C (fr)
GB (1) GB2586731B (fr)
MX (1) MX2020009161A (fr)
MY (1) MY195546A (fr)
SG (1) SG11202008507PA (fr)
TW (1) TW201940187A (fr)
UY (1) UY38139A (fr)
WO (1) WO2019173584A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102592150B1 (ko) * 2020-07-09 2023-10-20 크로다코리아 주식회사 살리실산 유도체를 포함하는 신규한 스핑고지질 및 이를 포함하는 조성물
US20220110996A1 (en) * 2020-10-12 2022-04-14 Wanda Lewis Moisturizing composition
CN113398020B (zh) * 2021-05-28 2022-06-17 植物医生(广东)生物科技有限公司 一种具有细致毛孔和提亮肤色功能的组合物及其应用
GB2628514A (en) * 2021-12-17 2024-09-25 Ocusoft Inc Cleansing, moisturizing and non-irritating topical compositions

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472432B1 (en) * 1997-11-17 2002-10-29 Nicholas V. Perricone Treatment of rosacea using lipoic acid
US6680062B2 (en) * 2001-10-05 2004-01-20 Color Access, Inc. Anti-irritating rosacea treatment
EP1465596A1 (fr) * 2002-01-18 2004-10-13 Control Delivery Systems, Inc. Systeme de gel polymere pour administration regulee de medicaments combines
FR2868702B1 (fr) * 2004-04-09 2006-12-22 Negma Lerads Soc Par Actions S Utilisation d'une base sphingoide associee a l'acide nicotinique ou un amide de l'acide nicotinique a titre d'agent depigmentant
FR2870125B1 (fr) * 2004-05-12 2010-03-26 Dermaconcept Jmc Formulation du type spot-on utile en cosmetologie et en dermatologie
AU2005327300A1 (en) * 2004-06-03 2006-08-17 Brown, James Steven Sanitizing composition and method of preparation
DE602005004139T2 (de) * 2005-06-30 2009-01-02 Evonik Goldschmidt Gmbh Verwendung von Salicyloyl-Sphingoidbase zur Behandlung oder Verhinderung von Cellilitis
DE102005057593A1 (de) 2005-07-08 2007-01-11 Schwan-Stabilo Cosmetics Gmbh & Co. Kg Zubereitung, insbesondere kosmetische Zubereitung, sowie ihre Herstellung und Verwendung
WO2009046116A1 (fr) * 2007-10-01 2009-04-09 Dennis Gross Produits de soin pour la peau contenant de multiples améliorateurs
DE102007049612A1 (de) * 2007-10-17 2009-06-10 Evonik Goldschmidt Gmbh Bioaktive Zusammensetzung für kosmetische Anwendungen
US8481006B2 (en) * 2008-04-25 2013-07-09 New Sunshine, Llc Melt formula
WO2013149323A1 (fr) * 2012-04-02 2013-10-10 Ntegrity Produits naturels pour soins de la peau
JP6046929B2 (ja) 2012-06-25 2016-12-21 株式会社キーエンス 光学測定装置
EP2740484A1 (fr) * 2012-12-05 2014-06-11 Lipotec, S.A. Compose utiles dans le traitement et/ou les soins de la peau, des muqueuses du cuir chevelu et/ou des cheveux et leur utilisation dans des compositions cosmétiques ou pharmaceutiques
US20140271509A1 (en) * 2013-03-15 2014-09-18 Inderma, Inc. Compositions for Skin Lightening and/or Brightening
CN103202780A (zh) * 2013-04-16 2013-07-17 纪艺琼 一种化妆品用纳米精华液及其制备方法
KR20180125171A (ko) * 2016-04-04 2018-11-22 오큐소프트, 인코포레이티드 눈꺼풀 위생을 유지하기 위한 조성물, 키트 및 방법
CN106176274B (zh) * 2016-08-26 2020-04-10 深圳市维琪医药研发有限公司 一种具有抗敏作用的多肽组合物
EP3175838A1 (fr) * 2017-03-16 2017-06-07 Evonik Degussa GmbH Formulations contenant une émulsion huile dans eau sous la forme d'une mousse contenant au moins un tensioactif

Also Published As

Publication number Publication date
US10993922B2 (en) 2021-05-04
GB2586731A (en) 2021-03-03
AU2019230097B2 (en) 2021-10-28
AU2019230097A1 (en) 2020-10-22
AR114376A1 (es) 2020-08-26
JP2023155497A (ja) 2023-10-20
WO2019173584A1 (fr) 2019-09-12
SG11202008507PA (en) 2020-10-29
US10576048B2 (en) 2020-03-03
MY195546A (en) 2023-01-31
US20200163909A1 (en) 2020-05-28
TW201940187A (zh) 2019-10-16
US20190274977A1 (en) 2019-09-12
GB2586731B (en) 2023-04-19
NZ768571A (en) 2024-01-26
CA3093428C (fr) 2023-07-11
KR20200131850A (ko) 2020-11-24
CN111836614A (zh) 2020-10-27
EP3761952B1 (fr) 2024-08-14
EP3761952C0 (fr) 2024-08-14
EP3761952A4 (fr) 2021-12-15
JP2021515021A (ja) 2021-06-17
UY38139A (es) 2019-08-30
EP3761952A1 (fr) 2021-01-13
MX2020009161A (es) 2022-10-13
GB202015640D0 (en) 2020-11-18

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