CA3092545A1 - Substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group - Google Patents
Substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group Download PDFInfo
- Publication number
- CA3092545A1 CA3092545A1 CA3092545A CA3092545A CA3092545A1 CA 3092545 A1 CA3092545 A1 CA 3092545A1 CA 3092545 A CA3092545 A CA 3092545A CA 3092545 A CA3092545 A CA 3092545A CA 3092545 A1 CA3092545 A1 CA 3092545A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- salt
- formula
- compounds
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862636367P | 2018-02-28 | 2018-02-28 | |
| US62/636,367 | 2018-02-28 | ||
| PCT/IB2019/051510 WO2019166937A1 (en) | 2018-02-28 | 2019-02-25 | Substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3092545A1 true CA3092545A1 (en) | 2019-09-06 |
Family
ID=65904502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3092545A Pending CA3092545A1 (en) | 2018-02-28 | 2019-02-25 | Substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11370788B2 (https=) |
| EP (1) | EP3759107B1 (https=) |
| JP (1) | JP7251893B2 (https=) |
| CN (1) | CN111788202B (https=) |
| CA (1) | CA3092545A1 (https=) |
| ES (1) | ES3003782T3 (https=) |
| WO (1) | WO2019166937A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113906027A (zh) * | 2019-06-12 | 2022-01-07 | 3M创新有限公司 | 具有N-1支链基团的苯乙基取代的咪唑并[4,5-c]喹啉化合物 |
| EP4178676B1 (en) | 2020-07-08 | 2026-04-15 | Solventum Intellectual Properties Company | N-1 branched imidazoquinolines, conjugates thereof, and methods |
| EP4263537A1 (en) * | 2020-12-16 | 2023-10-25 | 3M Innovative Properties Company | N-1 branched imidazoquinolines, conjugates thereof, and methods |
| CN116635394A (zh) * | 2020-12-16 | 2023-08-22 | 3M创新有限公司 | N-1支化咪唑并喹啉、其缀合物和方法 |
| EP4448519A1 (en) * | 2021-12-14 | 2024-10-23 | Solventum Intellectual Properties Company | N-1 triazole substituted imidazoquinolines, conjugates thereof, and methods |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700674A (en) | 1969-04-30 | 1972-10-24 | American Cyanamid Co | 4-alkylamino-3-nitroquinolines |
| IL73534A (en) * | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| US5389640A (en) | 1991-03-01 | 1995-02-14 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
| US5352784A (en) | 1993-07-15 | 1994-10-04 | Minnesota Mining And Manufacturing Company | Fused cycloalkylimidazopyridines |
| EP0708772B1 (en) | 1993-07-15 | 2000-08-23 | Minnesota Mining And Manufacturing Company | IMIDAZO [4,5-c]PYRIDIN-4-AMINES |
| KR100518903B1 (ko) | 1996-10-25 | 2005-10-06 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | Ｔｈ2 매개 질병 및 관련 질병의 치료용 면역 반응 조절 화합물 |
| JPH1180156A (ja) | 1997-09-04 | 1999-03-26 | Hokuriku Seiyaku Co Ltd | １−（置換アリール）アルキル−１ｈ−イミダゾピリジン−４−アミン誘導体 |
| UA67760C2 (uk) | 1997-12-11 | 2004-07-15 | Міннесота Майнінг Енд Мануфакчурінг Компані | Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки |
| US6110929A (en) | 1998-07-28 | 2000-08-29 | 3M Innovative Properties Company | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof |
| US6451810B1 (en) | 1999-06-10 | 2002-09-17 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
| US6331539B1 (en) | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
| US6677347B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamido ether substituted imidazoquinolines |
| US6664264B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
| UA75622C2 (en) * | 2000-12-08 | 2006-05-15 | 3M Innovative Properties Co | Aryl ether substituted imidazoquinolines, pharmaceutical composition based thereon |
| US6677348B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Aryl ether substituted imidazoquinolines |
| AU2004244962A1 (en) | 2003-04-10 | 2004-12-16 | 3M Innovative Properties Company | Delivery of immune response modifier compounds using metal-containing particulate support materials |
| BRPI0413558A (pt) | 2003-08-12 | 2006-10-17 | 3M Innovative Properties Co | compostos contendo imidazo substituìdo por hidroxilamina |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| WO2005051317A2 (en) | 2003-11-25 | 2005-06-09 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
| JP2007517035A (ja) * | 2003-12-29 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン |
| WO2005094531A2 (en) | 2004-03-24 | 2005-10-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
| CA2571360C (en) | 2004-06-18 | 2014-11-25 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines useful in inducing cytokine biosynthesis in animals |
| US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
| US7915281B2 (en) | 2004-06-18 | 2011-03-29 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method |
| JP5543068B2 (ja) * | 2004-12-30 | 2014-07-09 | スリーエム イノベイティブ プロパティズ カンパニー | キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物 |
| KR20080083270A (ko) | 2005-11-04 | 2008-09-17 | 콜레이 파마시티컬 그룹, 인코포레이티드 | 하이드록시 및 알콕시 치환된 1에이치 이미다조퀴놀린 및방법 |
| ES2617451T3 (es) | 2010-08-17 | 2017-06-19 | 3M Innovative Properties Company | Composiciones lipidadas de compuestos modificadores de la respuesta inmunitaria, formulaciones, y métodos |
| WO2013033345A1 (en) | 2011-08-30 | 2013-03-07 | Regents Of The University Of Minnesota | Immunomodulators and immunomodulator conjugates |
| MX377916B (es) | 2014-04-22 | 2025-03-10 | Hoffmann La Roche | Compuestos 4-amino-imidazoquinolina. |
| US10730871B2 (en) * | 2016-01-28 | 2020-08-04 | Regents Of The University Of Minnesota | Immunomodulators and immunomodulator conjugates |
| EP3728255B1 (en) | 2017-12-20 | 2022-01-26 | 3M Innovative Properties Company | Amide substituted imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier |
| EP3887369B1 (en) | 2018-11-26 | 2024-05-08 | Solventum Intellectual Properties Company | N-1 branched alkyl ether substituted imidazo[4,5-c]quinoline compounds, compositions, and methods |
-
2019
- 2019-02-25 JP JP2020545154A patent/JP7251893B2/ja active Active
- 2019-02-25 WO PCT/IB2019/051510 patent/WO2019166937A1/en not_active Ceased
- 2019-02-25 ES ES19713205T patent/ES3003782T3/es active Active
- 2019-02-25 US US15/733,519 patent/US11370788B2/en active Active
- 2019-02-25 CA CA3092545A patent/CA3092545A1/en active Pending
- 2019-02-25 EP EP19713205.3A patent/EP3759107B1/en active Active
- 2019-02-25 CN CN201980015722.5A patent/CN111788202B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021515755A (ja) | 2021-06-24 |
| US20200385379A1 (en) | 2020-12-10 |
| ES3003782T3 (en) | 2025-03-11 |
| EP3759107A1 (en) | 2021-01-06 |
| US11370788B2 (en) | 2022-06-28 |
| CN111788202B (zh) | 2024-03-01 |
| WO2019166937A1 (en) | 2019-09-06 |
| EP3759107B1 (en) | 2024-12-04 |
| JP7251893B2 (ja) | 2023-04-04 |
| CN111788202A (zh) | 2020-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20240226 |
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