CA3057104A1 - Stem cell-derived astrocytes, methods of making and methods of use - Google Patents

Stem cell-derived astrocytes, methods of making and methods of use Download PDF

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Publication number
CA3057104A1
CA3057104A1 CA3057104A CA3057104A CA3057104A1 CA 3057104 A1 CA3057104 A1 CA 3057104A1 CA 3057104 A CA3057104 A CA 3057104A CA 3057104 A CA3057104 A CA 3057104A CA 3057104 A1 CA3057104 A1 CA 3057104A1
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cells
nfia
days
cell
glial
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English (en)
French (fr)
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Lorenz Studer
Jason Tchieu
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Memorial Sloan Kettering Cancer Center
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Memorial Sloan Kettering Cancer Center
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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CA3057104A 2017-03-21 2018-03-21 Stem cell-derived astrocytes, methods of making and methods of use Pending CA3057104A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762474429P 2017-03-21 2017-03-21
US201762474596P 2017-03-21 2017-03-21
US62/474,596 2017-03-21
US62/474,429 2017-03-21
PCT/US2018/023551 WO2018175574A1 (en) 2017-03-21 2018-03-21 Stem cell-derived astrocytes, methods of making and methods of use

Publications (1)

Publication Number Publication Date
CA3057104A1 true CA3057104A1 (en) 2018-09-27

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Application Number Title Priority Date Filing Date
CA3057104A Pending CA3057104A1 (en) 2017-03-21 2018-03-21 Stem cell-derived astrocytes, methods of making and methods of use

Country Status (6)

Country Link
US (1) US20200024574A1 (https=)
EP (1) EP3600360A4 (https=)
JP (2) JP7471084B2 (https=)
AU (2) AU2018239426A1 (https=)
CA (1) CA3057104A1 (https=)
WO (1) WO2018175574A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3787613B1 (en) 2018-04-30 2026-03-11 Cedars-Sinai Medical Center Pkc activation for use in treating early onset sporadic parkinson's disease
AU2020370288B2 (en) * 2019-10-22 2026-02-12 Cedars-Sinai Medical Center Cortical neural progenitor cells from iPSCs
EP4206320A4 (en) * 2020-08-21 2025-02-12 JSR Corporation METHOD FOR CULTIVATION OF HUMAN INDUCED PLURIPOTENT STEM CELLS, CULTURE OF HUMAN INDUCED PLURIPOTENT STEM CELLS AND METHOD FOR THE PRODUCTION OF CEREBRAL ORGANOIDS
CN116406303B (zh) * 2020-09-04 2025-07-29 孔二艳 将gfap氨基酸位点作为神经退行性疾病治疗靶标的应用
EP4212615A4 (en) * 2020-09-10 2024-11-27 JSR Corporation METHOD FOR THE PRODUCTION OF ASTROCYTE-LIKE CELLS
CN111961650B (zh) * 2020-10-20 2023-06-13 士泽生物医药（苏州）有限公司 一种体外获得神经胶质细胞的方法及其应用
WO2022251254A1 (en) * 2021-05-24 2022-12-01 The Johns Hopkins University Pharmacological intervention of the arachidonic acid pathway to cure amyotrophic lateral sclerosis
CN116478923B (zh) * 2022-04-26 2024-01-02 浙江霍德生物工程有限公司 一种星形胶质细胞的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001654A (en) * 1994-01-28 1999-12-14 California Institute Of Technology Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors
JP5943533B2 (ja) * 2000-05-17 2016-07-06 アステリアス バイオセラピューティクス インコーポレイテッド 神経前駆細胞の集団
JP2009513269A (ja) * 2005-10-27 2009-04-02 アルフォース， ジャン−エリック ダブリュー． 無細胞血液産物をインキュベートすることによって生成される無細胞、生体吸収性の組織再生マトリックス
US20120207744A1 (en) * 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
US9453198B2 (en) * 2010-05-25 2016-09-27 Memorial Sloan Kettering Cancer Center Method of nociceptor differentiation of human embryonic stem cells and uses thereof
PT2773748T (pt) * 2011-11-04 2020-03-26 Memorial Sloan Kettering Cancer Center Neurónios dopaminérgicos (da) do mesencéfalo para enxerto
CN105960453A (zh) * 2013-10-01 2016-09-21 卡迪马干细胞有限公司 从人多能干细胞定向分化星形胶质细胞用于肌萎缩侧索硬化(als)的治疗和药物筛选
WO2016103269A1 (en) * 2014-12-23 2016-06-30 Ramot At Tel-Aviv University Ltd. Populations of neural progenitor cells and methods of producing and using same
WO2017057523A1 (ja) * 2015-09-29 2017-04-06 学校法人慶應義塾 アストロサイト様細胞及びその調製方法

Also Published As

Publication number Publication date
EP3600360A1 (en) 2020-02-05
JP2020513823A (ja) 2020-05-21
US20200024574A1 (en) 2020-01-23
AU2018239426A1 (en) 2019-10-03
EP3600360A4 (en) 2021-04-21
JP7471084B2 (ja) 2024-04-19
WO2018175574A1 (en) 2018-09-27
JP2022180634A (ja) 2022-12-06
AU2024203389A1 (en) 2024-06-06

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