CA3053243C - Pixel array medical systems, devices and methods - Google Patents
Pixel array medical systems, devices and methods Download PDFInfo
- Publication number
- CA3053243C CA3053243C CA3053243A CA3053243A CA3053243C CA 3053243 C CA3053243 C CA 3053243C CA 3053243 A CA3053243 A CA 3053243A CA 3053243 A CA3053243 A CA 3053243A CA 3053243 C CA3053243 C CA 3053243C
- Authority
- CA
- Canada
- Prior art keywords
- scalpet
- skin
- fractional
- vacuum
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract description 277
- 238000002271 resection Methods 0.000 claims abstract description 313
- 238000007443 liposuction Methods 0.000 claims abstract description 75
- 239000012528 membrane Substances 0.000 claims description 112
- 238000005520 cutting process Methods 0.000 claims description 48
- 230000035515 penetration Effects 0.000 claims description 21
- 238000012384 transportation and delivery Methods 0.000 claims description 13
- 230000006641 stabilisation Effects 0.000 claims description 12
- 238000011105 stabilization Methods 0.000 claims description 12
- 239000002131 composite material Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 6
- 229920000642 polymer Polymers 0.000 claims description 2
- 231100000241 scar Toxicity 0.000 abstract description 92
- 238000002324 minimally invasive surgery Methods 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 737
- 210000001519 tissue Anatomy 0.000 description 137
- 210000004379 membrane Anatomy 0.000 description 107
- 230000007547 defect Effects 0.000 description 94
- 210000004209 hair Anatomy 0.000 description 91
- 230000001464 adherent effect Effects 0.000 description 82
- 238000003306 harvesting Methods 0.000 description 79
- 238000011282 treatment Methods 0.000 description 54
- 230000037390 scarring Effects 0.000 description 49
- 208000032170 Congenital Abnormalities Diseases 0.000 description 47
- 238000003032 molecular docking Methods 0.000 description 33
- 201000010251 cutis laxa Diseases 0.000 description 32
- 239000000853 adhesive Substances 0.000 description 31
- 230000001070 adhesive effect Effects 0.000 description 31
- 210000004761 scalp Anatomy 0.000 description 31
- 239000000758 substrate Substances 0.000 description 31
- 239000013598 vector Substances 0.000 description 30
- 230000029663 wound healing Effects 0.000 description 30
- 210000004207 dermis Anatomy 0.000 description 29
- 239000010410 layer Substances 0.000 description 27
- 230000009467 reduction Effects 0.000 description 27
- 230000035876 healing Effects 0.000 description 26
- 238000002316 cosmetic surgery Methods 0.000 description 25
- 230000004044 response Effects 0.000 description 25
- 230000002500 effect on skin Effects 0.000 description 22
- 238000012546 transfer Methods 0.000 description 22
- 230000008569 process Effects 0.000 description 21
- 238000002054 transplantation Methods 0.000 description 20
- 238000013459 approach Methods 0.000 description 18
- 238000012377 drug delivery Methods 0.000 description 18
- 238000002347 injection Methods 0.000 description 18
- 239000007924 injection Substances 0.000 description 18
- 210000002615 epidermis Anatomy 0.000 description 17
- 206010049287 Lipodystrophy acquired Diseases 0.000 description 16
- 210000000481 breast Anatomy 0.000 description 16
- 230000008878 coupling Effects 0.000 description 16
- 238000010168 coupling process Methods 0.000 description 16
- 238000005859 coupling reaction Methods 0.000 description 16
- 208000006132 lipodystrophy Diseases 0.000 description 16
- 238000001356 surgical procedure Methods 0.000 description 16
- 230000007246 mechanism Effects 0.000 description 15
- 230000036961 partial effect Effects 0.000 description 15
- 201000004384 Alopecia Diseases 0.000 description 14
- 238000007906 compression Methods 0.000 description 14
- 230000006835 compression Effects 0.000 description 14
- 239000003814 drug Substances 0.000 description 14
- 210000004003 subcutaneous fat Anatomy 0.000 description 14
- 102000008186 Collagen Human genes 0.000 description 13
- 108010035532 Collagen Proteins 0.000 description 13
- 230000003111 delayed effect Effects 0.000 description 13
- 230000008021 deposition Effects 0.000 description 13
- 230000000694 effects Effects 0.000 description 13
- 210000003780 hair follicle Anatomy 0.000 description 13
- 206010029113 Neovascularisation Diseases 0.000 description 12
- 208000027418 Wounds and injury Diseases 0.000 description 12
- 210000003484 anatomy Anatomy 0.000 description 12
- 229920001436 collagen Polymers 0.000 description 12
- 229940079593 drug Drugs 0.000 description 12
- 230000006870 function Effects 0.000 description 12
- 239000011159 matrix material Substances 0.000 description 12
- 230000002829 reductive effect Effects 0.000 description 12
- 230000008602 contraction Effects 0.000 description 11
- 230000006378 damage Effects 0.000 description 11
- 238000001125 extrusion Methods 0.000 description 11
- 239000003589 local anesthetic agent Substances 0.000 description 11
- 230000002980 postoperative effect Effects 0.000 description 11
- 238000007920 subcutaneous administration Methods 0.000 description 11
- 208000032544 Cicatrix Diseases 0.000 description 10
- 230000035800 maturation Effects 0.000 description 10
- 210000005195 occipital scalp Anatomy 0.000 description 10
- 230000037387 scars Effects 0.000 description 10
- 206010052428 Wound Diseases 0.000 description 9
- 238000003491 array Methods 0.000 description 9
- 208000014674 injury Diseases 0.000 description 9
- 230000033001 locomotion Effects 0.000 description 9
- 238000005096 rolling process Methods 0.000 description 9
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 8
- 230000008901 benefit Effects 0.000 description 8
- 210000000689 upper leg Anatomy 0.000 description 8
- 206010039580 Scar Diseases 0.000 description 7
- 208000002847 Surgical Wound Diseases 0.000 description 7
- 231100000360 alopecia Toxicity 0.000 description 7
- 206010068168 androgenetic alopecia Diseases 0.000 description 7
- 230000000729 hypotrophic effect Effects 0.000 description 7
- 210000003127 knee Anatomy 0.000 description 7
- 230000002035 prolonged effect Effects 0.000 description 7
- 238000004904 shortening Methods 0.000 description 7
- 206010041235 Snoring Diseases 0.000 description 6
- 230000001413 cellular effect Effects 0.000 description 6
- 239000000049 pigment Substances 0.000 description 6
- 210000004872 soft tissue Anatomy 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 230000008733 trauma Effects 0.000 description 6
- 210000001015 abdomen Anatomy 0.000 description 5
- 210000000577 adipose tissue Anatomy 0.000 description 5
- 210000001217 buttock Anatomy 0.000 description 5
- 230000003902 lesion Effects 0.000 description 5
- 230000000670 limiting effect Effects 0.000 description 5
- 238000013507 mapping Methods 0.000 description 5
- 230000010534 mechanism of action Effects 0.000 description 5
- 230000000284 resting effect Effects 0.000 description 5
- 201000002859 sleep apnea Diseases 0.000 description 5
- 210000001584 soft palate Anatomy 0.000 description 5
- 230000003068 static effect Effects 0.000 description 5
- 210000000434 stratum corneum Anatomy 0.000 description 5
- 230000007704 transition Effects 0.000 description 5
- 206010006802 Burns second degree Diseases 0.000 description 4
- 208000035484 Cellulite Diseases 0.000 description 4
- 206010015150 Erythema Diseases 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 206010049752 Peau d'orange Diseases 0.000 description 4
- 238000002679 ablation Methods 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 230000004913 activation Effects 0.000 description 4
- 230000003698 anagen phase Effects 0.000 description 4
- 210000000617 arm Anatomy 0.000 description 4
- 210000001099 axilla Anatomy 0.000 description 4
- 238000001574 biopsy Methods 0.000 description 4
- 230000036232 cellulite Effects 0.000 description 4
- 230000000994 depressogenic effect Effects 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 229960001340 histamine Drugs 0.000 description 4
- 238000007726 management method Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 210000004877 mucosa Anatomy 0.000 description 4
- 230000036407 pain Effects 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 230000036558 skin tension Effects 0.000 description 4
- 230000000638 stimulation Effects 0.000 description 4
- 230000000699 topical effect Effects 0.000 description 4
- 206010006803 Burns third degree Diseases 0.000 description 3
- 206010010356 Congenital anomaly Diseases 0.000 description 3
- 206010015995 Eyelid ptosis Diseases 0.000 description 3
- 102000018997 Growth Hormone Human genes 0.000 description 3
- 108010051696 Growth Hormone Proteins 0.000 description 3
- 208000012287 Prolapse Diseases 0.000 description 3
- 210000001789 adipocyte Anatomy 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 230000036770 blood supply Effects 0.000 description 3
- 230000001010 compromised effect Effects 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 208000006111 contracture Diseases 0.000 description 3
- 238000012937 correction Methods 0.000 description 3
- 230000001351 cycling effect Effects 0.000 description 3
- 239000013536 elastomeric material Substances 0.000 description 3
- 230000005670 electromagnetic radiation Effects 0.000 description 3
- 231100000321 erythema Toxicity 0.000 description 3
- 210000000416 exudates and transudate Anatomy 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 210000002950 fibroblast Anatomy 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000009499 grossing Methods 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 239000000122 growth hormone Substances 0.000 description 3
- 230000003779 hair growth Effects 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 230000001969 hypertrophic effect Effects 0.000 description 3
- 230000036210 malignancy Effects 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 230000037311 normal skin Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 201000003004 ptosis Diseases 0.000 description 3
- 230000008439 repair process Effects 0.000 description 3
- 206010040882 skin lesion Diseases 0.000 description 3
- 231100000444 skin lesion Toxicity 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- 230000007480 spreading Effects 0.000 description 3
- 238000003892 spreading Methods 0.000 description 3
- 230000035899 viability Effects 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 2
- 206010006797 Burns first degree Diseases 0.000 description 2
- 206010051814 Eschar Diseases 0.000 description 2
- 206010063560 Excessive granulation tissue Diseases 0.000 description 2
- 206010064503 Excessive skin Diseases 0.000 description 2
- 241001313288 Labia Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010062575 Muscle contracture Diseases 0.000 description 2
- 208000000453 Skin Neoplasms Diseases 0.000 description 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 2
- 206010067775 Upper airway obstruction Diseases 0.000 description 2
- 230000003187 abdominal effect Effects 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- 230000003466 anti-cipated effect Effects 0.000 description 2
- 230000037444 atrophy Effects 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000036621 balding Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000007012 clinical effect Effects 0.000 description 2
- 238000005056 compaction Methods 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 238000001804 debridement Methods 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000001339 epidermal cell Anatomy 0.000 description 2
- 231100000333 eschar Toxicity 0.000 description 2
- 230000000763 evoking effect Effects 0.000 description 2
- 210000001723 extracellular space Anatomy 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 230000002068 genetic effect Effects 0.000 description 2
- 210000004907 gland Anatomy 0.000 description 2
- 210000001126 granulation tissue Anatomy 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 210000003630 histaminocyte Anatomy 0.000 description 2
- 230000000642 iatrogenic effect Effects 0.000 description 2
- 230000001900 immune effect Effects 0.000 description 2
- 230000003116 impacting effect Effects 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 238000005461 lubrication Methods 0.000 description 2
- 238000001000 micrograph Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000000394 mitotic effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000000651 myofibroblast Anatomy 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000003716 rejuvenation Effects 0.000 description 2
- 238000007634 remodeling Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 230000036548 skin texture Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- 210000000106 sweat gland Anatomy 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000003797 telogen phase Effects 0.000 description 2
- 230000028016 temperature homeostasis Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 230000008719 thickening Effects 0.000 description 2
- 238000011269 treatment regimen Methods 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 206010063659 Aversion Diseases 0.000 description 1
- 208000021657 Birth injury Diseases 0.000 description 1
- 206010004954 Birth trauma Diseases 0.000 description 1
- 208000035985 Body Odor Diseases 0.000 description 1
- 108030001720 Bontoxilysin Proteins 0.000 description 1
- 108010068426 Contractile Proteins Proteins 0.000 description 1
- 102000002585 Contractile Proteins Human genes 0.000 description 1
- 208000034423 Delivery Diseases 0.000 description 1
- 206010056340 Diabetic ulcer Diseases 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010062016 Immunosuppression Diseases 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 208000035901 Ischaemic ulcer Diseases 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 206010029098 Neoplasm skin Diseases 0.000 description 1
- 208000007256 Nevus Diseases 0.000 description 1
- 208000006787 Port-Wine Stain Diseases 0.000 description 1
- 208000004550 Postoperative Pain Diseases 0.000 description 1
- PPTYJKAXVCCBDU-UHFFFAOYSA-N Rohypnol Chemical compound N=1CC(=O)N(C)C2=CC=C([N+]([O-])=O)C=C2C=1C1=CC=CC=C1F PPTYJKAXVCCBDU-UHFFFAOYSA-N 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 206010040888 Skin malformation Diseases 0.000 description 1
- 206010040904 Skin odour abnormal Diseases 0.000 description 1
- 206010040925 Skin striae Diseases 0.000 description 1
- 108010057266 Type A Botulinum Toxins Proteins 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 208000000558 Varicose Ulcer Diseases 0.000 description 1
- 210000001766 X chromosome Anatomy 0.000 description 1
- 108700029631 X-Linked Genes Proteins 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000001944 accentuation Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000008365 aqueous carrier Substances 0.000 description 1
- 230000037365 barrier function of the epidermis Effects 0.000 description 1
- 210000002469 basement membrane Anatomy 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- 230000031018 biological processes and functions Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 229940089093 botox Drugs 0.000 description 1
- 229940053031 botulinum toxin Drugs 0.000 description 1
- 238000005219 brazing Methods 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000035614 depigmentation Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 238000007907 direct compression Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 201000000475 female stress incontinence Diseases 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229960004039 finasteride Drugs 0.000 description 1
- DBEPLOCGEIEOCV-WSBQPABSSA-N finasteride Chemical compound N([C@@H]1CC2)C(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)NC(C)(C)C)[C@@]2(C)CC1 DBEPLOCGEIEOCV-WSBQPABSSA-N 0.000 description 1
- 230000003325 follicular Effects 0.000 description 1
- 210000005200 frontal scalp Anatomy 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000003648 hair appearance Effects 0.000 description 1
- 210000004919 hair shaft Anatomy 0.000 description 1
- 238000002683 hand surgery Methods 0.000 description 1
- 208000002557 hidradenitis Diseases 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000001506 immunosuppresive effect Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000004130 lipolysis Effects 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000002690 local anesthesia Methods 0.000 description 1
- 229960005015 local anesthetics Drugs 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 206010025135 lupus erythematosus Diseases 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229960003632 minoxidil Drugs 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 210000005199 parietal scalp Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000000059 patterning Methods 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 239000002831 pharmacologic agent Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 238000013439 planning Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000035752 proliferative phase Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 210000005070 sphincter Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 238000010408 sweeping Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 231100000057 systemic toxicity Toxicity 0.000 description 1
- 229960003604 testosterone Drugs 0.000 description 1
- 230000009772 tissue formation Effects 0.000 description 1
- 229940126702 topical medication Drugs 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 210000001944 turbinate Anatomy 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000009677 vaginal delivery Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 230000010388 wound contraction Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/32053—Punch like cutting instruments, e.g. using a cylindrical or oval knife
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/322—Skin grafting apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/02—Devices for expanding tissue, e.g. skin tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/03—Automatic limiting or abutting means, e.g. for safety
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/42—Gynaecological or obstetrical instruments or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1402—Probes for open surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
- A61B2017/00398—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like using powered actuators, e.g. stepper motors, solenoids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00535—Surgical instruments, devices or methods pneumatically or hydraulically operated
- A61B2017/00561—Surgical instruments, devices or methods pneumatically or hydraulically operated creating a vacuum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00752—Hair removal or transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00769—Tattoo removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00792—Plastic surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00796—Breast surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/30—Surgical pincettes, i.e. surgical tweezers without pivotal connections
- A61B2017/306—Surgical pincettes, i.e. surgical tweezers without pivotal connections holding by means of suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B2017/320044—Blunt dissectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B2017/320052—Guides for cutting instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/32007—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic with suction or vacuum means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/322—Skin grafting apparatus
- A61B2017/3225—Skin grafting apparatus with processing of harvested tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3405—Needle locating or guiding means using mechanical guide means
- A61B2017/3409—Needle locating or guiding means using mechanical guide means including needle or instrument drives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00291—Anchoring means for temporary attachment of a device to tissue using suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/00458—Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
- A61B2018/00464—Subcutaneous fat, e.g. liposuction, lipolysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/0047—Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/00476—Hair follicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00601—Cutting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/03—Automatic limiting or abutting means, e.g. for safety
- A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3904—Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
- A61B2090/3908—Soft tissue, e.g. breast tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3933—Liquid markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3937—Visible markers
- A61B2090/395—Visible markers with marking agent for marking skin or other tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2217/00—General characteristics of surgical instruments
- A61B2217/002—Auxiliary appliance
- A61B2217/005—Auxiliary appliance with suction drainage system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
- A61B2218/007—Aspiration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/08—Lipoids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/04—Skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0034—Skin treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Mechanical Engineering (AREA)
- Dermatology (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Transplantation (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Otolaryngology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762456775P | 2017-02-09 | 2017-02-09 | |
| US62/456,775 | 2017-02-09 | ||
| US15/431,230 US11109887B2 (en) | 2013-12-06 | 2017-02-13 | Pixel array medical systems, devices and methods |
| US15/431,247 US10368904B2 (en) | 2013-12-06 | 2017-02-13 | Pixel array medical systems, devices and methods |
| US15/431,247 | 2017-02-13 | ||
| US15/431,230 | 2017-02-13 | ||
| US201762504844P | 2017-05-11 | 2017-05-11 | |
| US62/504,844 | 2017-05-11 | ||
| US15/812,952 US10773064B2 (en) | 2009-12-18 | 2017-11-14 | Skin treatment device and methods |
| US15/812,952 | 2017-11-14 | ||
| US15/821,258 US20180250027A1 (en) | 2012-12-06 | 2017-11-22 | Pixel array medical devices and methods |
| US15/821,258 | 2017-11-22 | ||
| US15/821,325 | 2017-11-22 | ||
| US15/821,325 US10335191B2 (en) | 2010-12-17 | 2017-11-22 | Pixel array medical devices and methods |
| PCT/US2018/017100 WO2018148214A2 (en) | 2014-10-02 | 2018-02-06 | Pixel array medical systems, devices and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3053243A1 CA3053243A1 (en) | 2018-08-16 |
| CA3053243C true CA3053243C (en) | 2022-05-31 |
Family
ID=67766781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3053243A Active CA3053243C (en) | 2017-02-09 | 2018-02-06 | Pixel array medical systems, devices and methods |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP7075568B2 (enExample) |
| KR (1) | KR20200042877A (enExample) |
| CN (1) | CN110891503B (enExample) |
| AU (1) | AU2018219219B2 (enExample) |
| CA (1) | CA3053243C (enExample) |
| SG (1) | SG11201907384TA (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113017783B (zh) * | 2021-03-02 | 2022-02-11 | 中国人民解放军总医院第四医学中心 | 一种锥体皮取皮器 |
| CN113397698B (zh) * | 2021-05-20 | 2023-04-18 | 东莞市飞越激光设备有限公司 | 一种保证高精度和高速度的激光切线装置 |
| TWI794105B (zh) * | 2022-05-26 | 2023-02-21 | 奇美醫療財團法人奇美醫院 | 陰道擴張器 |
| CN115429978B (zh) * | 2022-09-21 | 2023-06-30 | 苏州芙迈蕾医疗科技有限公司 | 一种智能电子注射器控制助推装置 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693064A (en) * | 1994-11-04 | 1997-12-02 | Arnold; James E. | Dermal punch for hair transplantation and methods |
| US5615690A (en) * | 1995-02-15 | 1997-04-01 | Symbiosis Corporation | Tissue core biopsy cannula |
| US6299620B1 (en) * | 1999-03-18 | 2001-10-09 | Aq Technologies, Inc. | Instruments and techniques for inducing neocollagenesis in skin treatments |
| US7144406B2 (en) * | 2003-03-26 | 2006-12-05 | New Hair Institute | Hair transplant device |
| EP2377404A1 (en) * | 2003-05-01 | 2011-10-19 | Medgenics, Inc. | A dermal micro-organ which is an explant of living tissue |
| WO2012145504A1 (en) * | 2011-04-20 | 2012-10-26 | Kci Licensing, Inc. | Skin graft devices and methods |
| EP3253308A4 (en) * | 2015-02-05 | 2018-10-24 | SRGI Holdings LLC | Pixel array medical systems, devices and methods |
-
2018
- 2018-02-06 KR KR1020197026150A patent/KR20200042877A/ko not_active Abandoned
- 2018-02-06 SG SG11201907384TA patent/SG11201907384TA/en unknown
- 2018-02-06 CA CA3053243A patent/CA3053243C/en active Active
- 2018-02-06 JP JP2019543350A patent/JP7075568B2/ja active Active
- 2018-02-06 AU AU2018219219A patent/AU2018219219B2/en not_active Expired - Fee Related
- 2018-02-06 CN CN201880023723.XA patent/CN110891503B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018219219A1 (en) | 2019-09-05 |
| CN110891503B (zh) | 2024-05-31 |
| SG11201907384TA (en) | 2019-09-27 |
| CN110891503A (zh) | 2020-03-17 |
| AU2018219219B2 (en) | 2020-11-26 |
| KR20200042877A (ko) | 2020-04-24 |
| JP2020507401A (ja) | 2020-03-12 |
| CA3053243A1 (en) | 2018-08-16 |
| JP7075568B2 (ja) | 2022-05-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11844546B2 (en) | Pixel array medical systems, devices and methods | |
| US11839402B2 (en) | Pixel array medical systems, devices and methods | |
| US10772658B2 (en) | Pixel array medical systems, devices and methods | |
| US10736653B2 (en) | Pixel array medical systems, devices and methods | |
| US10335190B2 (en) | Pixel array medical systems, devices and methods | |
| AU2017218014B2 (en) | Pixel array medical systems, devices and methods | |
| CA3023223A1 (en) | Pixel array medical systems, devices and methods | |
| US11278309B2 (en) | Pixel array medical systems, devices and methods | |
| CA3053243C (en) | Pixel array medical systems, devices and methods | |
| US11000310B2 (en) | Pixel array medical systems, devices and methods | |
| US20240197358A1 (en) | Pixel Array Medical Systems, Devices and Methods | |
| US20240252203A1 (en) | Pixel array medical systems, devices and methods | |
| US20240216009A1 (en) | Pixel array medical systems, devices and methods | |
| US20210030434A1 (en) | Pixel array medical systems, devices and methods | |
| US20200029990A1 (en) | Pixel array medical systems, devices and methods |