CA3051797A1 - Binding agents - Google Patents
Binding agents Download PDFInfo
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- CA3051797A1 CA3051797A1 CA3051797A CA3051797A CA3051797A1 CA 3051797 A1 CA3051797 A1 CA 3051797A1 CA 3051797 A CA3051797 A CA 3051797A CA 3051797 A CA3051797 A CA 3051797A CA 3051797 A1 CA3051797 A1 CA 3051797A1
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- seq
- gitr
- antigen
- antibody
- binding portion
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1701351.7 | 2017-01-27 | ||
| GBGB1701351.7A GB201701351D0 (en) | 2017-01-27 | 2017-01-27 | Binding agents |
| GB1713296.0 | 2017-08-18 | ||
| GBGB1713296.0A GB201713296D0 (en) | 2017-08-18 | 2017-08-18 | Binding agents |
| PCT/GB2018/050239 WO2018138521A1 (en) | 2017-01-27 | 2018-01-26 | Binding agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3051797A1 true CA3051797A1 (en) | 2018-08-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA3051797A Pending CA3051797A1 (en) | 2017-01-27 | 2018-01-26 | Binding agents |
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| Country | Link |
|---|---|
| US (2) | US10457736B2 (OSRAM) |
| EP (1) | EP3574013A1 (OSRAM) |
| JP (1) | JP7169296B2 (OSRAM) |
| KR (1) | KR20190112299A (OSRAM) |
| CN (1) | CN110475787A (OSRAM) |
| AU (1) | AU2018213124A1 (OSRAM) |
| BR (1) | BR112019015453A2 (OSRAM) |
| CA (1) | CA3051797A1 (OSRAM) |
| IL (1) | IL268288A (OSRAM) |
| MX (1) | MX2019008905A (OSRAM) |
| RU (1) | RU2019125975A (OSRAM) |
| SG (1) | SG11201906963QA (OSRAM) |
| WO (1) | WO2018138521A1 (OSRAM) |
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| KR102123322B1 (ko) | 2019-11-01 | 2020-06-16 | 주식회사 미래에스엠 | 상판 오픈형 다용도 선반 |
| KR20210132400A (ko) | 2020-04-27 | 2021-11-04 | 유미경 | 다용도 선반 |
| TW202246334A (zh) * | 2021-02-02 | 2022-12-01 | 美商美國禮來大藥廠 | Gitr拮抗劑及其使用方法 |
| CN117813327A (zh) * | 2021-05-10 | 2024-04-02 | 美帝马布生物公司 | 抗gitr抗体及其用途 |
| WO2023060144A1 (en) * | 2021-10-05 | 2023-04-13 | Lanier Biotherapeutics | Monoclonal antibodies to il-25 and uses thereof |
| IL314907A (en) | 2022-03-15 | 2024-10-01 | Yeda Res & Dev | Antibodies against GITR and their uses |
| CN118050505B (zh) * | 2024-04-15 | 2024-06-21 | 南京佰抗生物科技有限公司 | 一种多联检荧光免疫层析检测卡 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2602777C (en) * | 2005-03-25 | 2018-12-11 | Tolerrx, Inc. | Gitr binding molecules and uses therefor |
| SG178991A1 (en) | 2009-09-03 | 2012-04-27 | Schering Corp | Anti-gitr antibodies |
| TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
| SG10201912986PA (en) | 2014-05-28 | 2020-02-27 | Agenus Inc | Anti-gitr antibodies and methods of use thereof |
| CA2951234C (en) | 2014-06-06 | 2022-05-31 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof |
| MA41044A (fr) * | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
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2018
- 2018-01-26 MX MX2019008905A patent/MX2019008905A/es unknown
- 2018-01-26 KR KR1020197025095A patent/KR20190112299A/ko not_active Ceased
- 2018-01-26 EP EP18702550.7A patent/EP3574013A1/en not_active Withdrawn
- 2018-01-26 SG SG11201906963QA patent/SG11201906963QA/en unknown
- 2018-01-26 JP JP2019561375A patent/JP7169296B2/ja active Active
- 2018-01-26 BR BR112019015453-1A patent/BR112019015453A2/pt not_active IP Right Cessation
- 2018-01-26 WO PCT/GB2018/050239 patent/WO2018138521A1/en not_active Ceased
- 2018-01-26 CA CA3051797A patent/CA3051797A1/en active Pending
- 2018-01-26 AU AU2018213124A patent/AU2018213124A1/en not_active Abandoned
- 2018-01-26 CN CN201880020490.8A patent/CN110475787A/zh active Pending
- 2018-01-26 RU RU2019125975A patent/RU2019125975A/ru unknown
- 2018-08-17 US US16/104,434 patent/US10457736B2/en active Active
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2019
- 2019-05-29 US US16/424,676 patent/US20190375846A1/en not_active Abandoned
- 2019-07-28 IL IL268288A patent/IL268288A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020505075A (ja) | 2020-02-20 |
| RU2019125975A (ru) | 2021-03-01 |
| CN110475787A (zh) | 2019-11-19 |
| KR20190112299A (ko) | 2019-10-04 |
| MX2019008905A (es) | 2019-11-18 |
| RU2019125975A3 (OSRAM) | 2021-10-01 |
| AU2018213124A1 (en) | 2019-09-12 |
| BR112019015453A2 (pt) | 2020-03-24 |
| US20190375846A1 (en) | 2019-12-12 |
| SG11201906963QA (en) | 2019-08-27 |
| JP7169296B2 (ja) | 2022-11-10 |
| US10457736B2 (en) | 2019-10-29 |
| WO2018138521A1 (en) | 2018-08-02 |
| EP3574013A1 (en) | 2019-12-04 |
| US20190010241A1 (en) | 2019-01-10 |
| IL268288A (en) | 2019-09-26 |
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