CA3047281A1 - System and method configured to provide extracorporeal support for premature fetus - Google Patents
System and method configured to provide extracorporeal support for premature fetus Download PDFInfo
- Publication number
- CA3047281A1 CA3047281A1 CA3047281A CA3047281A CA3047281A1 CA 3047281 A1 CA3047281 A1 CA 3047281A1 CA 3047281 A CA3047281 A CA 3047281A CA 3047281 A CA3047281 A CA 3047281A CA 3047281 A1 CA3047281 A1 CA 3047281A1
- Authority
- CA
- Canada
- Prior art keywords
- chamber
- interior space
- fetus
- wall
- shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000003754 fetus Anatomy 0.000 title claims abstract description 117
- 230000002028 premature Effects 0.000 title abstract description 18
- 238000000034 method Methods 0.000 title description 28
- 239000012530 fluid Substances 0.000 claims abstract description 131
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000001301 oxygen Substances 0.000 claims abstract description 20
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 20
- 230000033001 locomotion Effects 0.000 claims abstract description 5
- 239000007789 gas Substances 0.000 claims description 93
- 239000008280 blood Substances 0.000 claims description 29
- 210000004369 blood Anatomy 0.000 claims description 29
- 238000001914 filtration Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 10
- 230000007246 mechanism Effects 0.000 abstract description 12
- 230000035899 viability Effects 0.000 abstract description 7
- 230000012010 growth Effects 0.000 abstract description 3
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 6
- 206010036590 Premature baby Diseases 0.000 description 6
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- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 4
- 230000000903 blocking effect Effects 0.000 description 4
- 229960002897 heparin Drugs 0.000 description 4
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- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 230000037452 priming Effects 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
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- 241000894006 Bacteria Species 0.000 description 2
- 241001631457 Cannula Species 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 208000005107 Premature Birth Diseases 0.000 description 2
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- 230000036316 preload Effects 0.000 description 2
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- 230000002685 pulmonary effect Effects 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 206010009192 Circulatory collapse Diseases 0.000 description 1
- 108700011014 Congenital Deficiency of Pulmonary Surfactant Protein B Proteins 0.000 description 1
- 208000027205 Congenital disease Diseases 0.000 description 1
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- 208000032589 Diaphragmatic Congenital Hernias Diseases 0.000 description 1
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- 241000282412 Homo Species 0.000 description 1
- 102000008100 Human Serum Albumin Human genes 0.000 description 1
- 108091006905 Human Serum Albumin Proteins 0.000 description 1
- 208000032754 Infant Death Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
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- 208000004210 Pressure Ulcer Diseases 0.000 description 1
- 206010037407 Pulmonary hypoplasia Diseases 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 206010067726 Shortened cervix Diseases 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
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- 238000004458 analytical method Methods 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
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- 230000033228 biological regulation Effects 0.000 description 1
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- 230000001684 chronic effect Effects 0.000 description 1
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- 239000000356 contaminant Substances 0.000 description 1
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- 239000008151 electrolyte solution Substances 0.000 description 1
- 238000002618 extracorporeal membrane oxygenation Methods 0.000 description 1
- 230000004578 fetal growth Effects 0.000 description 1
- 210000002458 fetal heart Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
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- 230000002458 infectious effect Effects 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 210000001006 meconium Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000032633 organ maturation Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 230000003169 placental effect Effects 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000306 polymethylpentene Polymers 0.000 description 1
- 239000011116 polymethylpentene Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
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- 238000002271 resection Methods 0.000 description 1
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- 229940125723 sedative agent Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 206010040560 shock Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000003195 tocolytic effect Effects 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G11/00—Baby-incubators; Couveuses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G10/00—Treatment rooms or enclosures for medical purposes
- A61G10/04—Oxygen tents ; Oxygen hoods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G11/00—Baby-incubators; Couveuses
- A61G11/005—Baby-incubators; Couveuses with movable walls, e.g. for accessing the inside, removable walls
- A61G11/006—Baby-incubators; Couveuses with movable walls, e.g. for accessing the inside, removable walls by pivoting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G11/00—Baby-incubators; Couveuses
- A61G11/009—Baby-incubators; Couveuses with hand insertion windows, e.g. in the walls
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G2203/00—General characteristics of devices
- A61G2203/30—General characteristics of devices characterised by sensor means
- A61G2203/34—General characteristics of devices characterised by sensor means for pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G2203/00—General characteristics of devices
- A61G2203/70—General characteristics of devices with special adaptations, e.g. for safety or comfort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2240/00—Specially adapted for neonatal use
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pediatric Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434100P | 2016-12-14 | 2016-12-14 | |
| US62/434,100 | 2016-12-14 | ||
| PCT/US2017/065950 WO2018111956A1 (en) | 2016-12-14 | 2017-12-13 | System and method configured to provide extracorporeal support for premature fetus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3047281A1 true CA3047281A1 (en) | 2018-06-21 |
Family
ID=62559830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3047281A Pending CA3047281A1 (en) | 2016-12-14 | 2017-12-13 | System and method configured to provide extracorporeal support for premature fetus |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11471351B2 (enExample) |
| EP (2) | EP4252795A3 (enExample) |
| JP (2) | JP7249280B2 (enExample) |
| KR (1) | KR20190100241A (enExample) |
| AU (3) | AU2017376139B2 (enExample) |
| CA (1) | CA3047281A1 (enExample) |
| ES (1) | ES2951734T3 (enExample) |
| MX (1) | MX2019006987A (enExample) |
| RU (1) | RU2019121939A (enExample) |
| WO (1) | WO2018111956A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2907206T3 (es) | 2015-06-19 | 2022-04-22 | Childrens Hospital Philadelphia | Aparato para soporte extracorpóreo de feto prematuro |
| WO2018111956A1 (en) * | 2016-12-14 | 2018-06-21 | The Children's Hospital Of Philadelphia | System and method configured to provide extracorporeal support for premature fetus |
| US10441490B2 (en) * | 2018-01-09 | 2019-10-15 | Amnion Life, LLC | Systems, methods, and devices for artificial placentas and amniotic bed incubators |
| US12268802B2 (en) * | 2019-04-09 | 2025-04-08 | The Children's Hospital Of Philadelphia | Oxygenator for use with extracorporeal support of premature fetus |
| CN110123558A (zh) * | 2019-05-21 | 2019-08-16 | 滕玲玲 | 一种产科辅助监护装置 |
| WO2021222349A1 (en) * | 2020-04-29 | 2021-11-04 | The Children's Hospital Of Philadelphia | Cannula insertion system and methods of using the same |
| CA3192675A1 (en) * | 2020-09-15 | 2022-03-24 | Alan W. Flake | Chamber assembly for premature fetus |
| WO2022232468A1 (en) * | 2021-04-28 | 2022-11-03 | The Children's Hospital Of Philadelphia | Transfer tray and priming cart for neonatal cannulation and related methods |
| EP4137170A1 (en) * | 2021-07-29 | 2023-02-22 | Tim Bast | Purge fluid generator for membrane oxygenation |
| EP4419113A4 (en) * | 2021-10-20 | 2025-11-26 | Childrens Hospital Philadelphia | PHYSIOLOGICAL SALINE SOLUTION AND ITS PROCESSES OF MANUFACTURING AND USING |
| US12310786B2 (en) | 2021-10-21 | 2025-05-27 | Canon Medical Systems Corporation | Ultrasonic diagnostic apparatus and ultrasonic diagnostic method |
| US12472297B2 (en) | 2021-12-22 | 2025-11-18 | Vitara Biomedical, Inc. | Cannulator collet latch |
| US20250186666A1 (en) * | 2022-03-09 | 2025-06-12 | The Children's Hospital Of Philadelphia | System and method of treatment for premature fetus |
| AU2022478492A1 (en) | 2022-09-14 | 2025-04-03 | Vitara Biomedical, Inc. | Oxygenator for neonates |
| WO2024058775A1 (en) | 2022-09-14 | 2024-03-21 | The Children's Hospital Of Philadelphia | Systems and methods for oxygenating blood, passive oxygenation circuits, and neonatal extracorporeal support systems |
| AU2024226929A1 (en) | 2023-02-20 | 2025-09-18 | Vitara Biomedical, Inc. | Cannula system including variable shape tip |
| DE102023110564A1 (de) * | 2023-04-25 | 2024-10-31 | Elisabeth Krenkler | Künstliche Gebärmutter |
| EP4663177A1 (en) * | 2024-06-12 | 2025-12-17 | Hospital Sant Joan de Deu | Chamber system for mammalian fetal development and maturation |
| CN119746195A (zh) * | 2025-01-13 | 2025-04-04 | 北京清瀚医疗科技有限公司 | 一种体外生命支持系统 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2723660A (en) | 1954-07-22 | 1955-11-15 | Emanuel M Greenberg | Artificial uterus |
| US4048684A (en) | 1975-12-10 | 1977-09-20 | The Board Of Trustees Of Leland Stanford Junior University | Infant waterbed |
| FR2522963A1 (fr) | 1982-03-12 | 1983-09-16 | Calhene | Installation pour le confinement et le transport en atmosphere sterile d'etres humains, notamment de nouveau-nes |
| CH664892A5 (de) | 1984-05-18 | 1988-04-15 | Ameda Ag | Inkubator. |
| US4796605A (en) | 1986-07-11 | 1989-01-10 | Atom Kabushiki Kaisha | Incubator |
| IT218019Z2 (it) | 1989-09-08 | 1992-03-05 | Enea | Dispositivo protettivo individuale, portatile ad isolamento totale conatmosfera controllata |
| EP0447256A3 (en) | 1990-03-16 | 1992-01-08 | Hitachi, Ltd. | Methods and apparatus for incubation and sterilization |
| US5218958A (en) | 1991-02-21 | 1993-06-15 | Cooper William I | Placental chamber - artificial uterus |
| US5207639A (en) * | 1991-02-21 | 1993-05-04 | Cooper William I | Fetal lung apparatus |
| US5308310A (en) | 1992-08-18 | 1994-05-03 | Vitaltrends Technology, Inc. | Plethysmograph system and air-tight sealing assembly therefor |
| US5624375A (en) | 1995-04-21 | 1997-04-29 | Ohmeda Inc. | Incubator tilt mechanism |
| CN1308549A (zh) | 1998-05-08 | 2001-08-15 | 爱德华兹生命科学公司 | 带有整体热交换器/蓄存器的低灌注膜片充氧器 |
| EP1231883B1 (en) * | 1999-11-15 | 2008-09-10 | Draeger Medical Systems, Inc. | Infant care apparatus with movable infant support |
| US10155082B2 (en) * | 2002-04-10 | 2018-12-18 | Baxter International Inc. | Enhanced signal detection for access disconnection systems |
| PE20040074A1 (es) | 2002-07-12 | 2004-02-25 | Univ Pontificia Catolica Peru | Burbuja artificial neonatal |
| US20040193096A1 (en) | 2003-03-25 | 2004-09-30 | Cooper William Isaac | Conceptus chamber |
| US7108653B2 (en) * | 2003-12-04 | 2006-09-19 | Datex-Ohmeda, Inc. | Canopy adjustable mounting system for infant warming apparatus |
| US20060270911A1 (en) * | 2005-04-08 | 2006-11-30 | Voegele James W | Tissue retraction device |
| EP1886071A1 (en) | 2005-05-27 | 2008-02-13 | Ralph Ellerker (1795) Ltd | Apparatus for use to create a controlled environment |
| US20070010005A1 (en) * | 2005-07-08 | 2007-01-11 | James Sitzmann | Neonatal support system and related devices and methods of use |
| US8585968B2 (en) | 2006-04-21 | 2013-11-19 | Scott W. Morley | Method and system for purging moisture from an oxygenator |
| US7763097B2 (en) | 2006-06-08 | 2010-07-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Devices, systems and methods for reducing the concentration of a chemical entity in fluids |
| RU2376969C1 (ru) | 2008-06-11 | 2009-12-27 | Государственное образовательное учреждение высшего профессионального образования "Саратовский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" | Устройство для выхаживания недоношенных новорожденных |
| WO2010078395A2 (en) | 2008-12-31 | 2010-07-08 | World Medical Technologies, Llc | Modular neonatal intensive care system |
| DE102009037015A1 (de) | 2009-08-07 | 2011-02-17 | Michael Hajek | Vorrichtung und Verfahren zur Eliminierung von bioschädlichen Stoffen aus Körperflüssigkeiten |
| WO2013026148A1 (en) | 2011-08-23 | 2013-02-28 | Mcmaster University | Artificial placenta |
| CA2846590A1 (en) | 2011-08-25 | 2013-02-28 | Breonics, Inc. | Organ chamber for ex vivo warm perfusion |
| JP5912792B2 (ja) * | 2012-04-11 | 2016-04-27 | アトムメディカル株式会社 | 保育器 |
| JP5828802B2 (ja) * | 2012-05-07 | 2015-12-09 | 英伸 太田 | 早産児用の抱っこ型次世代人工保育器。 |
| ES2886598T3 (es) * | 2013-03-15 | 2021-12-20 | Childrens Hospital Philadelphia | Sistema de soporte vital extracorpóreo |
| DE102013018919B4 (de) * | 2013-11-13 | 2018-12-27 | Drägerwerk AG & Co. KGaA | Wärmetherapiegerät für Neu- und Frühgeborene |
| CN203663028U (zh) | 2014-01-17 | 2014-06-25 | 张洪娟 | 用于产科医疗的新生儿恒温箱 |
| JP6377477B2 (ja) * | 2014-09-25 | 2018-08-22 | テルモ株式会社 | クランプ装置 |
| ES2907206T3 (es) * | 2015-06-19 | 2022-04-22 | Childrens Hospital Philadelphia | Aparato para soporte extracorpóreo de feto prematuro |
| EP3370676B1 (en) | 2015-11-06 | 2023-12-13 | Amnion Life, LLC | Premature infant amniotic bath incubator |
| WO2018111956A1 (en) | 2016-12-14 | 2018-06-21 | The Children's Hospital Of Philadelphia | System and method configured to provide extracorporeal support for premature fetus |
| WO2018171905A1 (de) * | 2017-03-21 | 2018-09-27 | Universitätsklinikum Halle (Saale) | Künstliches gebärmuttersystem und plazenta |
-
2017
- 2017-12-13 WO PCT/US2017/065950 patent/WO2018111956A1/en not_active Ceased
- 2017-12-13 MX MX2019006987A patent/MX2019006987A/es unknown
- 2017-12-13 ES ES17881013T patent/ES2951734T3/es active Active
- 2017-12-13 EP EP23177586.7A patent/EP4252795A3/en active Pending
- 2017-12-13 RU RU2019121939A patent/RU2019121939A/ru not_active Application Discontinuation
- 2017-12-13 KR KR1020197020061A patent/KR20190100241A/ko not_active Withdrawn
- 2017-12-13 AU AU2017376139A patent/AU2017376139B2/en active Active
- 2017-12-13 EP EP17881013.1A patent/EP3554446B1/en active Active
- 2017-12-13 US US16/469,192 patent/US11471351B2/en active Active
- 2017-12-13 CA CA3047281A patent/CA3047281A1/en active Pending
- 2017-12-13 JP JP2019531626A patent/JP7249280B2/ja active Active
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2022
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2023
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2025
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Also Published As
| Publication number | Publication date |
|---|---|
| ES2951734T3 (es) | 2023-10-24 |
| AU2023201760A1 (en) | 2023-04-27 |
| EP3554446A1 (en) | 2019-10-23 |
| EP4252795A3 (en) | 2023-12-27 |
| EP4252795A2 (en) | 2023-10-04 |
| AU2025201665A1 (en) | 2025-03-27 |
| AU2017376139A1 (en) | 2019-06-20 |
| US20190380900A1 (en) | 2019-12-19 |
| JP7566962B2 (ja) | 2024-10-15 |
| WO2018111956A1 (en) | 2018-06-21 |
| US11471351B2 (en) | 2022-10-18 |
| AU2017376139B2 (en) | 2022-12-22 |
| EP3554446B1 (en) | 2023-06-07 |
| JP7249280B2 (ja) | 2023-03-30 |
| EP3554446A4 (en) | 2020-07-22 |
| MX2019006987A (es) | 2019-08-16 |
| EP3554446C0 (en) | 2023-06-07 |
| RU2019121939A (ru) | 2021-01-15 |
| US20230000706A1 (en) | 2023-01-05 |
| JP2023072088A (ja) | 2023-05-23 |
| KR20190100241A (ko) | 2019-08-28 |
| JP2020501679A (ja) | 2020-01-23 |
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