CA3042246A1 - Compositions and methods for the production of compounds - Google Patents
Compositions and methods for the production of compounds Download PDFInfo
- Publication number
- CA3042246A1 CA3042246A1 CA3042246A CA3042246A CA3042246A1 CA 3042246 A1 CA3042246 A1 CA 3042246A1 CA 3042246 A CA3042246 A CA 3042246A CA 3042246 A CA3042246 A CA 3042246A CA 3042246 A1 CA3042246 A1 CA 3042246A1
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- CA
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- Prior art keywords
- polyketide synthase
- polyketide
- seq
- nucleic acid
- modules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A61P17/06—Antipsoriatics
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
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- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
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- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
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- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/485—Streptomyces aureofaciens
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- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/55—Streptomyces hygroscopicus
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- Organic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Tropical Medicine & Parasitology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201662414410P | 2016-10-28 | 2016-10-28 | |
| US62/414,410 | 2016-10-28 | ||
| PCT/US2017/058800 WO2018081590A1 (en) | 2016-10-28 | 2017-10-27 | Compositions and methods for the production of compounds |
Publications (1)
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| CA3042246A1 true CA3042246A1 (en) | 2018-05-03 |
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| CA3042246A Abandoned CA3042246A1 (en) | 2016-10-28 | 2017-10-27 | Compositions and methods for the production of compounds |
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| AU (1) | AU2017350898A1 (enExample) |
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| WO (1) | WO2018081590A1 (enExample) |
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| JPWO2021241593A1 (enExample) * | 2020-05-26 | 2021-12-02 | ||
| EP4222167A1 (en) | 2020-09-30 | 2023-08-09 | Nobell Foods, Inc. | Recombinant milk proteins and food compositions comprising the same |
| US10894812B1 (en) | 2020-09-30 | 2021-01-19 | Alpine Roads, Inc. | Recombinant milk proteins |
| US10947552B1 (en) | 2020-09-30 | 2021-03-16 | Alpine Roads, Inc. | Recombinant fusion proteins for producing milk proteins in plants |
| US20250283057A1 (en) * | 2021-05-25 | 2025-09-11 | Spiber Inc. | Method for Producing Plasmid, and Plasmid |
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| US6960453B1 (en) * | 1996-07-05 | 2005-11-01 | Biotica Technology Limited | Hybrid polyketide synthases combining heterologous loading and extender modules |
| EP0910633B1 (en) * | 1996-07-05 | 2009-12-09 | Biotica Technology Limited | Hybrid polyketide synthase I gene |
| CA2343880C (en) * | 1998-10-02 | 2008-08-26 | Kosan Biosciences, Inc. | Polyketide synthase enzymes and recombinant dna constructs therefor |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| CA2359801A1 (en) * | 1999-02-09 | 2000-08-17 | Rajesh S. Gokhale | Methods to mediate polyketide synthase module effectiveness |
| US20030153053A1 (en) * | 2001-08-06 | 2003-08-14 | Ralph Reid | Methods for altering polyketide synthase genes |
| US10233431B2 (en) * | 2014-02-26 | 2019-03-19 | The Regents Of The University Of California | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases |
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2017
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- 2017-10-27 EP EP17863519.9A patent/EP3532055A4/en not_active Withdrawn
- 2017-10-27 JP JP2019523693A patent/JP2019533470A/ja active Pending
- 2017-10-27 US US16/345,595 patent/US20190264184A1/en not_active Abandoned
- 2017-10-27 CA CA3042246A patent/CA3042246A1/en not_active Abandoned
- 2017-10-27 KR KR1020197015344A patent/KR102561694B1/ko active Active
- 2017-10-27 CN CN201780081161.XA patent/CN110418642A/zh active Pending
- 2017-10-27 WO PCT/US2017/058800 patent/WO2018081590A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN110418642A (zh) | 2019-11-05 |
| KR102561694B1 (ko) | 2023-07-28 |
| KR20190099397A (ko) | 2019-08-27 |
| WO2018081590A1 (en) | 2018-05-03 |
| JP2019533470A (ja) | 2019-11-21 |
| EP3532055A4 (en) | 2020-10-21 |
| EP3532055A1 (en) | 2019-09-04 |
| AU2017350898A1 (en) | 2019-06-13 |
| US20190264184A1 (en) | 2019-08-29 |
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