AU2017350898A1 - Compositions and methods for the production of compounds - Google Patents

Compositions and methods for the production of compounds Download PDF

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Publication number
AU2017350898A1
AU2017350898A1 AU2017350898A AU2017350898A AU2017350898A1 AU 2017350898 A1 AU2017350898 A1 AU 2017350898A1 AU 2017350898 A AU2017350898 A AU 2017350898A AU 2017350898 A AU2017350898 A AU 2017350898A AU 2017350898 A1 AU2017350898 A1 AU 2017350898A1
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AU
Australia
Prior art keywords
polyketide
polyketide synthase
seq
nucleic acid
modules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2017350898A
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English (en)
Inventor
Brian R. Bowman
Marc CHEVRETTE
Daniel C. Gray
Anna LI
Enhu LI
Jay P. Morgenstern
Keith Robison
Dan UDWARY
Gregory L. Verdine
Pam Shouping WANG
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Ginkgo Bioworks Inc
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Ginkgo Bioworks Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ginkgo Bioworks Inc filed Critical Ginkgo Bioworks Inc
Publication of AU2017350898A1 publication Critical patent/AU2017350898A1/en
Abandoned legal-status Critical Current

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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
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    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
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    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
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    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
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    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/485Streptomyces aureofaciens
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    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/55Streptomyces hygroscopicus

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  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2017350898A 2016-10-28 2017-10-27 Compositions and methods for the production of compounds Abandoned AU2017350898A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662414410P 2016-10-28 2016-10-28
US62/414,410 2016-10-28
PCT/US2017/058800 WO2018081590A1 (en) 2016-10-28 2017-10-27 Compositions and methods for the production of compounds

Publications (1)

Publication Number Publication Date
AU2017350898A1 true AU2017350898A1 (en) 2019-06-13

Family

ID=62025506

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017350898A Abandoned AU2017350898A1 (en) 2016-10-28 2017-10-27 Compositions and methods for the production of compounds

Country Status (8)

Country Link
US (1) US20190264184A1 (enExample)
EP (1) EP3532055A4 (enExample)
JP (1) JP2019533470A (enExample)
KR (1) KR102561694B1 (enExample)
CN (1) CN110418642A (enExample)
AU (1) AU2017350898A1 (enExample)
CA (1) CA3042246A1 (enExample)
WO (1) WO2018081590A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2021241593A1 (enExample) * 2020-05-26 2021-12-02
EP4222167A1 (en) 2020-09-30 2023-08-09 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
US20250283057A1 (en) * 2021-05-25 2025-09-11 Spiber Inc. Method for Producing Plasmid, and Plasmid

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960453B1 (en) * 1996-07-05 2005-11-01 Biotica Technology Limited Hybrid polyketide synthases combining heterologous loading and extender modules
EP0910633B1 (en) * 1996-07-05 2009-12-09 Biotica Technology Limited Hybrid polyketide synthase I gene
CA2343880C (en) * 1998-10-02 2008-08-26 Kosan Biosciences, Inc. Polyketide synthase enzymes and recombinant dna constructs therefor
US7217856B2 (en) * 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
CA2359801A1 (en) * 1999-02-09 2000-08-17 Rajesh S. Gokhale Methods to mediate polyketide synthase module effectiveness
US20030153053A1 (en) * 2001-08-06 2003-08-14 Ralph Reid Methods for altering polyketide synthase genes
US10233431B2 (en) * 2014-02-26 2019-03-19 The Regents Of The University Of California Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases

Also Published As

Publication number Publication date
CN110418642A (zh) 2019-11-05
KR102561694B1 (ko) 2023-07-28
KR20190099397A (ko) 2019-08-27
CA3042246A1 (en) 2018-05-03
WO2018081590A1 (en) 2018-05-03
JP2019533470A (ja) 2019-11-21
EP3532055A4 (en) 2020-10-21
EP3532055A1 (en) 2019-09-04
US20190264184A1 (en) 2019-08-29

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted