CA3036694A1 - Treatment of multiple sclerosis with chs-131 - Google Patents

Treatment of multiple sclerosis with chs-131 Download PDF

Info

Publication number
CA3036694A1
CA3036694A1 CA3036694A CA3036694A CA3036694A1 CA 3036694 A1 CA3036694 A1 CA 3036694A1 CA 3036694 A CA3036694 A CA 3036694A CA 3036694 A CA3036694 A CA 3036694A CA 3036694 A1 CA3036694 A1 CA 3036694A1
Authority
CA
Canada
Prior art keywords
effective amount
therapeutically effective
compound
multiple sclerosis
milligrams
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3036694A
Other languages
English (en)
French (fr)
Inventor
Barbara FINCK
Robert ZIVADINOV
Hong Tang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intekrin Therapeutics Inc
Original Assignee
Intekrin Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intekrin Therapeutics Inc filed Critical Intekrin Therapeutics Inc
Publication of CA3036694A1 publication Critical patent/CA3036694A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3036694A 2016-09-13 2017-09-13 Treatment of multiple sclerosis with chs-131 Abandoned CA3036694A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662394046P 2016-09-13 2016-09-13
US62/394,046 2016-09-13
US201662436356P 2016-12-19 2016-12-19
US62/436,356 2016-12-19
US201762460868P 2017-02-19 2017-02-19
US62/460,868 2017-02-19
US201762491071P 2017-04-27 2017-04-27
US62/491,071 2017-04-27
PCT/US2017/051414 WO2018053040A1 (en) 2016-09-13 2017-09-13 Treatment of multiple sclerosis with chs-131

Publications (1)

Publication Number Publication Date
CA3036694A1 true CA3036694A1 (en) 2018-03-22

Family

ID=61619253

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3036694A Abandoned CA3036694A1 (en) 2016-09-13 2017-09-13 Treatment of multiple sclerosis with chs-131

Country Status (12)

Country Link
US (1) US20190224186A1 (OSRAM)
EP (1) EP3512512A4 (OSRAM)
JP (1) JP2019531286A (OSRAM)
KR (1) KR20190064583A (OSRAM)
CN (1) CN110461318A (OSRAM)
AU (1) AU2017326261A1 (OSRAM)
BR (1) BR112019004791A2 (OSRAM)
CA (1) CA3036694A1 (OSRAM)
IL (1) IL265259A (OSRAM)
MX (1) MX2019002901A (OSRAM)
SG (1) SG10202102198RA (OSRAM)
WO (1) WO2018053040A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
AU2016229982B2 (en) 2015-03-09 2020-06-18 Intekrin Therapeutics, Inc. Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
JP2020515639A (ja) 2017-04-03 2020-05-28 コヒラス・バイオサイエンシズ・インコーポレイテッド 進行性核上性麻痺の処置のためのPPARγアゴニスト
EA201992364A1 (ru) * 2018-04-02 2020-03-23 Кохерус Байосайенсис Инк. АГОНИСТ PPARγ ДЛЯ ЛЕЧЕНИЯ ПРОГРЕССИРУЮЩЕГО НАДЪЯДЕРНОГО ПАРАЛИЧА

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
HK1218865A1 (zh) * 2012-10-12 2017-03-17 Teva Pharmaceutical Industries Ltd. 用於降低多发性硬化症中丘脑损伤的拉喹莫德
EP2950798B1 (en) * 2013-01-30 2021-05-12 Intekrin Therapeutics, Inc. Ppar-gamma agonist for treatment of multiple sclerosis

Also Published As

Publication number Publication date
BR112019004791A2 (pt) 2019-06-04
EP3512512A1 (en) 2019-07-24
SG10202102198RA (en) 2021-04-29
AU2017326261A1 (en) 2019-04-04
IL265259A (en) 2019-05-30
MX2019002901A (es) 2019-09-26
EP3512512A4 (en) 2020-06-03
KR20190064583A (ko) 2019-06-10
JP2019531286A (ja) 2019-10-31
WO2018053040A1 (en) 2018-03-22
CN110461318A (zh) 2019-11-15
US20190224186A1 (en) 2019-07-25

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20231228