CA3034258A1 - Ppar.gamma. agonist for treatment of blood cancers - Google Patents

Ppar.gamma. agonist for treatment of blood cancers Download PDF

Info

Publication number
CA3034258A1
CA3034258A1 CA3034258A CA3034258A CA3034258A1 CA 3034258 A1 CA3034258 A1 CA 3034258A1 CA 3034258 A CA3034258 A CA 3034258A CA 3034258 A CA3034258 A CA 3034258A CA 3034258 A1 CA3034258 A1 CA 3034258A1
Authority
CA
Canada
Prior art keywords
leukemia
subject
therapeutically effective
effective amount
milligrams
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3034258A
Other languages
English (en)
French (fr)
Inventor
Christos Mantzoros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intekrin Therapeutics Inc
Original Assignee
Intekrin Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intekrin Therapeutics Inc filed Critical Intekrin Therapeutics Inc
Publication of CA3034258A1 publication Critical patent/CA3034258A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
CA3034258A 2016-08-18 2017-08-18 Ppar.gamma. agonist for treatment of blood cancers Pending CA3034258A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662376749P 2016-08-18 2016-08-18
US62/376,749 2016-08-18
PCT/US2017/047578 WO2018035446A1 (en) 2016-08-18 2017-08-18 PPARγ AGONIST FOR TREATMENT OF BLOOD CANCERS

Publications (1)

Publication Number Publication Date
CA3034258A1 true CA3034258A1 (en) 2018-02-22

Family

ID=61197183

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3034258A Pending CA3034258A1 (en) 2016-08-18 2017-08-18 Ppar.gamma. agonist for treatment of blood cancers

Country Status (12)

Country Link
US (1) US20210379049A1 (OSRAM)
EP (1) EP3500268A4 (OSRAM)
JP (2) JP2019524888A (OSRAM)
KR (1) KR20190064573A (OSRAM)
CN (1) CN110461329A (OSRAM)
AU (1) AU2017313839A1 (OSRAM)
BR (1) BR112019003130A2 (OSRAM)
CA (1) CA3034258A1 (OSRAM)
EA (1) EA201990512A1 (OSRAM)
MX (1) MX2019001979A (OSRAM)
SG (2) SG10202101501PA (OSRAM)
WO (1) WO2018035446A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016229982B2 (en) 2015-03-09 2020-06-18 Intekrin Therapeutics, Inc. Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
JP2020515639A (ja) 2017-04-03 2020-05-28 コヒラス・バイオサイエンシズ・インコーポレイテッド 進行性核上性麻痺の処置のためのPPARγアゴニスト
WO2020243058A1 (en) * 2019-05-30 2020-12-03 Coherus Biosciences, Inc. Compositions and methods to treat cancer
JP2022104746A (ja) * 2020-12-29 2022-07-11 国立研究開発法人国立がん研究センター 抗がん剤
JP2022104747A (ja) * 2020-12-29 2022-07-11 国立研究開発法人国立がん研究センター 抗ウイルス剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3018186B1 (ja) * 1999-03-09 2000-03-13 大阪大学長 抗炎症剤、単球系細胞の増殖抑制剤
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
JP2010265216A (ja) * 2009-05-14 2010-11-25 Takeda Chem Ind Ltd 複素環化合物
EP2950798B1 (en) * 2013-01-30 2021-05-12 Intekrin Therapeutics, Inc. Ppar-gamma agonist for treatment of multiple sclerosis
WO2017211830A1 (en) * 2016-06-08 2017-12-14 Support-Venture Gmbh Pharmaceutical combinations for treating cancer

Also Published As

Publication number Publication date
SG11201901320WA (en) 2019-03-28
WO2018035446A1 (en) 2018-02-22
KR20190064573A (ko) 2019-06-10
MX2019001979A (es) 2019-09-19
AU2017313839A1 (en) 2019-03-07
BR112019003130A2 (pt) 2019-05-21
JP2019524888A (ja) 2019-09-05
EP3500268A1 (en) 2019-06-26
CN110461329A (zh) 2019-11-15
SG10202101501PA (en) 2021-03-30
EP3500268A4 (en) 2020-04-15
US20210379049A1 (en) 2021-12-09
EA201990512A1 (ru) 2019-08-30
JP2022116304A (ja) 2022-08-09

Similar Documents

Publication Publication Date Title
JP2022116304A (ja) 血液がんの治療のためのPPARγアゴニスト
KR102860817B1 (ko) 트라디피턴트에 의한 치료 방법
CN102908347A (zh) 取代的喹啉衍生物在治疗耐药性分枝杆菌性疾病中的用途
EP4008329B1 (en) Isoxazoline compounds for use in treating demodicosis
KR20140056212A (ko) 골수성증식 신생물과 같은 암 치료에서의 파노비노스타트와 룩소리티닙의 조합물
US20190321364A1 (en) Use of neutrophil elastase inhibitors in liver disease
JP6145946B2 (ja) 併用als療法
JP2020520963A (ja) 抑うつ障害の処置
RU2494736C2 (ru) Комбинация, включающая паклитаксел, для лечения рака яичников
WO2019222564A1 (en) Methods and compositions for treatment of alzheimer's disease
JP2024523126A (ja) Nrh、narh、及びそれらの還元誘導体を用いた免疫関連障害、腎障害、肝障害、溶血性障害、及び酸化的ストレス関連障害の処置
AU2020275208B2 (en) Formulation of delgocitinib in the form of a cream
TWI760306B (zh) 供治療癌症之口服投予紫杉醇及P-gp抑制劑的治療性組合
KR102009932B1 (ko) 허혈로 인한 뉴런 손상을 감소시키기 위한 아포에쿼린
Aboubakr Evaluation of bioequivalence of two enrofloxacin formulations after intramuscular administration in goats
US10172857B2 (en) Boosting the effect of methotrexate through the combined use with lipophilic statins
WO2021023291A1 (zh) 原黄素在肺癌治疗中的应用
KR20210095652A (ko) 스테로이드에 대한 내성을 극복하기 위한 글루타르이미드 유도체
JP2025532582A (ja) 組み合わせ
JP2025513474A (ja) 好中球性皮膚疾患の治療
EP1707199A1 (en) Oxaprozin or closely related compound for the treatment and prevention of pruritus
US20220401459A1 (en) New application of chemokine receptor ccr6 inhibitor in preventing recurrence of psoriasis
WO2020234780A1 (en) Methods of treating asthma using a bruton's tyrosine kinase inhibitor
JP2025512582A (ja) ジテルペン化合物誘導体またはその塩のアトピー性皮膚炎を予防・治療する医薬品の調製における使用
EP4228754A1 (en) Methods of managing side effects of a vasopressin receptor antagonist therapy

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220817

EEER Examination request

Effective date: 20220817

EEER Examination request

Effective date: 20220817