CA3012404A1 - Means and methods for staging, typing and treating a cancerous disease - Google Patents

Means and methods for staging, typing and treating a cancerous disease Download PDF

Info

Publication number
CA3012404A1
CA3012404A1 CA3012404A CA3012404A CA3012404A1 CA 3012404 A1 CA3012404 A1 CA 3012404A1 CA 3012404 A CA3012404 A CA 3012404A CA 3012404 A CA3012404 A CA 3012404A CA 3012404 A1 CA3012404 A1 CA 3012404A1
Authority
CA
Canada
Prior art keywords
dcc
cells
somatic
cancer
dccs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3012404A
Other languages
English (en)
French (fr)
Inventor
Christoph Klein
Sebastian SCHEITLER
Melanie WERNER-KLEIN
Martin Hoffmann
Isabelle HODAK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Regensburg
Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Original Assignee
Universitaet Regensburg
Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Regensburg, Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV filed Critical Universitaet Regensburg
Publication of CA3012404A1 publication Critical patent/CA3012404A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA3012404A 2016-01-27 2017-01-27 Means and methods for staging, typing and treating a cancerous disease Pending CA3012404A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16152883.1A EP3199641B1 (en) 2016-01-27 2016-01-27 Means and methods for staging, typing and treating a cancerous disease
EP16152883.1 2016-01-27
PCT/EP2017/051789 WO2017129753A1 (en) 2016-01-27 2017-01-27 Means and methods for staging, typing and treating a cancerous disease

Publications (1)

Publication Number Publication Date
CA3012404A1 true CA3012404A1 (en) 2017-08-03

Family

ID=55310656

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3012404A Pending CA3012404A1 (en) 2016-01-27 2017-01-27 Means and methods for staging, typing and treating a cancerous disease

Country Status (10)

Country Link
US (1) US11702701B2 (enExample)
EP (2) EP3199641B1 (enExample)
JP (1) JP2019508032A (enExample)
KR (1) KR20180102674A (enExample)
CN (1) CN108770360B (enExample)
AU (1) AU2017211976B2 (enExample)
CA (1) CA3012404A1 (enExample)
ES (1) ES2905208T3 (enExample)
SG (1) SG11201805990XA (enExample)
WO (1) WO2017129753A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018134254A1 (en) 2017-01-17 2018-07-26 Heparegenix Gmbh Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673541B1 (en) 1998-09-18 2004-01-06 Micromet Ag DNA amplification of a single cell
WO2002037113A2 (en) * 2000-11-03 2002-05-10 Michael Giesing Clinical and functional validation of targets from disseminated cancer cells
ITRM20110149A1 (it) * 2011-03-25 2012-09-26 Massimo Zollo Biomarcatore per la rilevazione di cellule tumorali circolanti e relativi metodi e kit di rilevazione.
WO2013009632A2 (en) * 2011-07-08 2013-01-17 The University Of Utah Research Foundation Methods of detecting hereditary cancer predisposition
EP3211099A1 (en) * 2011-12-10 2017-08-30 Abbott Molecular Inc. Materials and methods for diagnosis of malignant melanoma and prognosis of metastasis of malignant melanoma
WO2015023551A1 (en) * 2013-08-13 2015-02-19 Bionumerik Pharmaceuticals, Inc. Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types
US10273538B2 (en) 2014-02-05 2019-04-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Error-free sequencing of DNA

Also Published As

Publication number Publication date
AU2017211976B2 (en) 2022-09-22
US11702701B2 (en) 2023-07-18
JP2019508032A (ja) 2019-03-28
AU2017211976A1 (en) 2018-08-02
CN108770360A (zh) 2018-11-06
EP3199641B1 (en) 2021-09-29
KR20180102674A (ko) 2018-09-17
CN108770360B (zh) 2022-06-14
WO2017129753A8 (en) 2017-10-19
EP3199641A1 (en) 2017-08-02
WO2017129753A1 (en) 2017-08-03
ES2905208T3 (es) 2022-04-07
SG11201805990XA (en) 2018-08-30
US20190062845A1 (en) 2019-02-28
EP3408411A1 (en) 2018-12-05

Similar Documents

Publication Publication Date Title
Radke et al. The genomic and transcriptional landscape of primary central nervous system lymphoma
Guo et al. DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
US20220010385A1 (en) Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
Perrone et al. PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
Staudt et al. The biology of human lymphoid malignancies revealed by gene expression profiling
Hodgkinson et al. Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer
Rahrmann et al. Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis
Ren et al. Gene expression predicts dormant metastatic breast cancer cell phenotype
Lorenzo-Martín et al. VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
Zhai et al. Arid1a inactivation in an Apc‐and Pten‐defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival
Vincenzo et al. Application of molecular biology of differentiated thyroid cancer for clinical prognostication
Guijarro et al. Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling
Gulati et al. Molecular analysis of primary and metastatic sites in patients with renal cell carcinoma
Mellai et al. Promoter hypermethylation of the EMP3 gene in a series of 229 human gliomas
US11702701B2 (en) Means and methods for staging, typing and treating a cancerous disease
Gimeno-Valiente et al. DNA methylation co-operates with genomic alterations during non-small cell lung cancer evolution
Powers et al. The molecular pathology of sarcomas
Ghatalia et al. Correction to: Prognostic impact of immune gene expression signature and tumor infiltrating immune cells in localized clear cell renal cell carcinoma
Repo et al. Functional assay for assessment of pathogenicity of BAP1 variants
Gürgen et al. A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies
Park et al. High p16INK4A expression in glioblastoma is associated with senescence phenotype and better prognosis
CN110684843B (zh) 罹癌个体样本中生物标记的用途
Fadl et al. Anaplastic large cell lymphomas with equivocal DUSP22 FISH results: recommendations for clinical reporting and diagnostic evaluation
Cramer et al. Forward genetic screening in engineered colorectal cancer organoids identifies novel regulators of metastasis
Jacobi et al. EZH2 alters aggressive variant prostate cancer subtype evolution, but is not required for neuroendocrine prostate cancer

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220127

EEER Examination request

Effective date: 20220127

EEER Examination request

Effective date: 20220127

EEER Examination request

Effective date: 20220127

EEER Examination request

Effective date: 20220127

EEER Examination request

Effective date: 20220127