CA3011429A1 - Treatment of cancer with combinations of immunoregulatory agents - Google Patents
Treatment of cancer with combinations of immunoregulatory agents Download PDFInfo
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- CA3011429A1 CA3011429A1 CA3011429A CA3011429A CA3011429A1 CA 3011429 A1 CA3011429 A1 CA 3011429A1 CA 3011429 A CA3011429 A CA 3011429A CA 3011429 A CA3011429 A CA 3011429A CA 3011429 A1 CA3011429 A1 CA 3011429A1
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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Landscapes
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| US62/301,981 | 2016-03-01 | ||
| PCT/US2017/014375 WO2017127707A1 (en) | 2016-01-21 | 2017-01-20 | Treatment of cancer with combinations of immunoregulatory agents |
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| CN111247172B (zh) * | 2017-10-18 | 2023-11-14 | 四十七公司 | 基于抗cd47剂的卵巢癌疗法 |
| PL3697819T3 (pl) * | 2017-10-18 | 2023-03-06 | Forty Seven, Inc. | Leczenie nowotworu złośliwego jajnika anty-cd47 i anty-pd-l1 |
| CA3083946A1 (en) | 2017-12-01 | 2019-06-06 | Seattle Genetics, Inc. | Cd47 antibodies and uses thereof for treating cancer |
| WO2019109357A1 (zh) * | 2017-12-08 | 2019-06-13 | 杭州翰思生物医药有限公司 | 抗pd-1/cd47的双特异性抗体及其应用 |
| EP4129336B1 (en) | 2018-02-12 | 2025-05-07 | Forty Seven, LLC | Anti-cd47 agent-based treatment of cd20-positive cancer |
| US11591390B2 (en) | 2018-09-27 | 2023-02-28 | Celgene Corporation | SIRP-α binding proteins and methods of use thereof |
| MY205933A (en) | 2018-09-27 | 2024-11-21 | Celgene Corp | Sirp-alpha binding proteins and methods of use thereof |
| WO2020072445A1 (en) * | 2018-10-01 | 2020-04-09 | Verastem, Inc. | Combination therapies |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CN109517073A (zh) * | 2018-11-30 | 2019-03-26 | 北京泽勤生物医药有限公司 | 一种靶向治疗肿瘤的融合肽及其应用 |
| EP3898676A1 (en) * | 2018-12-21 | 2021-10-27 | OSE Immunotherapeutics | Bifunctional anti-pd-1/sirpa molecule |
| WO2020163692A1 (en) * | 2019-02-08 | 2020-08-13 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of cutaneous t cell lymphoma with targeting of cd47 pathway |
| US20220169725A1 (en) * | 2019-03-08 | 2022-06-02 | North Carolina State University | Bio-responsive antibody complexes for enhanced immunotherapy |
| EP4003375A4 (en) * | 2019-07-31 | 2023-09-06 | Forty Seven, Inc. | DEPLETION DIETS FOR MODIFIED T CELL OR NK CELL THERAPY |
| US11702474B2 (en) | 2019-12-17 | 2023-07-18 | Pfizer Inc. | Antibodies specific for CD47, PD-L1, and uses thereof |
| JP2023546679A (ja) * | 2020-10-22 | 2023-11-07 | アクティニウム ファーマシューティカルズ インコーポレイテッド | がん治療における放射免疫療法とｃｄ４７遮断の併用 |
| EP4274853A4 (en) * | 2021-01-05 | 2024-12-04 | National Institute Of Biological Sciences, Beijing | BISPECIFIC ANTIBODY TARGETING GPC3 AND CD47 |
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| US8377448B2 (en) | 2006-05-15 | 2013-02-19 | The Board Of Trustees Of The Leland Standford Junior University | CD47 related compositions and methods for treating immunological diseases and disorders |
| AU2010295661B2 (en) * | 2009-09-15 | 2015-04-30 | The Board Of Trustees Of The Leland Stanford Junior University | Synergistic anti-CD47 therapy for hematologic cancers |
| CN102939303A (zh) * | 2009-12-22 | 2013-02-20 | 诺瓦提斯公司 | 四价cd47-抗体恒定区融合蛋白用于治疗 |
| ES2616010T3 (es) | 2010-05-14 | 2017-06-09 | The Board Of Trustees Of The Leland Stanford Junior University | Anticuerpos monoclonales humanizados y quiméricos a CD47 |
| WO2013112942A1 (en) * | 2012-01-25 | 2013-08-01 | Dna Trix, Inc. | Biomarkers and combination therapies using oncolytic virus and immunomodulation |
| EP2925782B1 (en) * | 2012-12-03 | 2020-01-22 | NovImmune SA | Anti-cd47 antibodies and methods of use thereof |
| RU2015122228A (ru) * | 2012-12-12 | 2017-01-19 | Васкулокс Инк. | Терапевтические антитела к CD47 |
| AU2014238105B2 (en) * | 2013-03-15 | 2018-11-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for achieving therapeutically effective doses of anti-CD47 agents |
| TWI681969B (zh) * | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| WO2016023001A1 (en) * | 2014-08-08 | 2016-02-11 | The Board Of Trustees Of The Leland Stanford Junior University | Multispecific high affinity pd-1 agents and methods of use |
| EP4186927B1 (en) * | 2015-10-21 | 2025-04-23 | Ose Immunotherapeutics | Methods and compositions for modifying macrophage polarization into pro-inflammatory cells to treat cancer |
| CN107459578B (zh) * | 2016-05-31 | 2021-11-26 | 泰州迈博太科药业有限公司 | 一种靶向cd47与pd-l1的双功能融合蛋白 |
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| EP3405499A4 (en) | 2020-03-18 |
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| AU2024202900A1 (en) | 2024-05-23 |
| AU2017210224A1 (en) | 2018-08-02 |
| SG11201806110QA (en) | 2018-08-30 |
| JP2023085370A (ja) | 2023-06-20 |
| KR20180102628A (ko) | 2018-09-17 |
| AU2017210224B2 (en) | 2024-02-08 |
| KR102833922B1 (ko) | 2025-07-15 |
| US20170210803A1 (en) | 2017-07-27 |
| EP3405499A1 (en) | 2018-11-28 |
| WO2017127707A1 (en) | 2017-07-27 |
| JP2019506400A (ja) | 2019-03-07 |
| CN109071676A (zh) | 2018-12-21 |
| JP7026047B2 (ja) | 2022-02-25 |
| US20210230276A1 (en) | 2021-07-29 |
| US20250066473A1 (en) | 2025-02-27 |
| EP4070812A1 (en) | 2022-10-12 |
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