CA3009716C - Generic method for the stabilization of specific rna - Google Patents
Generic method for the stabilization of specific rna Download PDFInfo
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- CA3009716C CA3009716C CA3009716A CA3009716A CA3009716C CA 3009716 C CA3009716 C CA 3009716C CA 3009716 A CA3009716 A CA 3009716A CA 3009716 A CA3009716 A CA 3009716A CA 3009716 C CA3009716 C CA 3009716C
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- oligonucleotides
- rna
- stranded rna
- amplification
- nucleic acid
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US201562271614P | 2015-12-28 | 2015-12-28 | |
| US62/271,614 | 2015-12-28 | ||
| PCT/EP2016/082696 WO2017114823A1 (en) | 2015-12-28 | 2016-12-27 | Generic method for the stabilization of specific rna |
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| CA3009716A1 CA3009716A1 (en) | 2017-07-06 |
| CA3009716C true CA3009716C (en) | 2021-11-02 |
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| JP7434742B2 (ja) * | 2019-07-22 | 2024-02-21 | 株式会社島津製作所 | 核酸の検出方法 |
| GB2594317B (en) * | 2020-04-23 | 2022-05-25 | Univ Johannesburg Witwatersrand | SARS-CoV-2 Diagnostic control compositions |
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| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| PT726962E (pt) * | 1991-12-23 | 2006-10-31 | Chiron Corp | Sondas para hiv para uso em ensaios de hibridacao em sanduiche em fase de solucao |
| GB2285445A (en) | 1993-12-06 | 1995-07-12 | Pna Diagnostics As | Protecting nucleic acids and methods of analysis |
| US5939262A (en) * | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
| US5853990A (en) * | 1996-07-26 | 1998-12-29 | Edward E. Winger | Real time homogeneous nucleotide assay |
| AU3117101A (en) * | 2000-01-28 | 2001-08-07 | Scripps Research Inst | Synthetic internal ribosome entry sites and methods of identifying same |
| US20110009466A1 (en) | 2007-08-29 | 2011-01-13 | President And Fellows Of Harvard College | Methods of increasing gene expression through rna protection |
| EP2240606B1 (en) * | 2008-01-14 | 2016-10-12 | Applied Biosystems, LLC | Compositions, methods, and kits for detecting ribonucleic acid |
| US20120052502A1 (en) | 2010-08-30 | 2012-03-01 | Samsung Techwin Co., Ltd. | Real-time pcr detection using stabilized probes |
| US20150267192A1 (en) | 2012-06-08 | 2015-09-24 | Shire Human Genetic Therapies, Inc. | Nuclease resistant polynucleotides and uses thereof |
| JP2016528897A (ja) * | 2013-08-16 | 2016-09-23 | ラナ セラピューティクス インコーポレイテッド | Ｒｎａを調節するための組成物および方法 |
| CA2976576A1 (en) * | 2015-02-13 | 2016-08-18 | Translate Bio Ma, Inc. | Compositions and methods for modulating rna |
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Also Published As
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| WO2017114823A1 (en) | 2017-07-06 |
| JP6880034B2 (ja) | 2021-06-02 |
| ES2886605T3 (es) | 2021-12-20 |
| EP3397775A1 (en) | 2018-11-07 |
| CA3009716A1 (en) | 2017-07-06 |
| EP3397775B1 (en) | 2021-06-30 |
| CN108291252A (zh) | 2018-07-17 |
| CN108291252B (zh) | 2022-05-13 |
| JP2019506849A (ja) | 2019-03-14 |
| US10689689B2 (en) | 2020-06-23 |
| US20170183720A1 (en) | 2017-06-29 |
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