CA3008975A1 - Human alpha-n-acetylgalactosaminidase polypeptide - Google Patents
Human alpha-n-acetylgalactosaminidase polypeptide Download PDFInfo
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- CA3008975A1 CA3008975A1 CA3008975A CA3008975A CA3008975A1 CA 3008975 A1 CA3008975 A1 CA 3008975A1 CA 3008975 A CA3008975 A CA 3008975A CA 3008975 A CA3008975 A CA 3008975A CA 3008975 A1 CA3008975 A1 CA 3008975A1
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- amino acid
- polypeptide
- human
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01049—Alpha-N-acetylgalactosaminidase (3.2.1.49)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
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- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15202729 | 2015-12-24 | ||
| EP15202729.8 | 2015-12-24 | ||
| PCT/EP2016/082304 WO2017109034A1 (en) | 2015-12-24 | 2016-12-22 | Human alpha-n-acetylgalactosaminidase polypeptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3008975A1 true CA3008975A1 (en) | 2017-06-29 |
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|---|---|---|---|
| CA3008975A Pending CA3008975A1 (en) | 2015-12-24 | 2016-12-22 | Human alpha-n-acetylgalactosaminidase polypeptide |
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| Country | Link |
|---|---|
| US (1) | US11040114B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3393501B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6956417B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180088919A (cg-RX-API-DMAC7.html) |
| CA (1) | CA3008975A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017109034A1 (cg-RX-API-DMAC7.html) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3393501B1 (en) * | 2015-12-24 | 2023-06-07 | Oxyrane UK Limited | Human alpha-n-acetylgalactosaminidase polypeptide |
| WO2019051297A1 (en) * | 2017-09-08 | 2019-03-14 | The Nemours Foundation | AGENT, DEVICE AND BLOOD CIRCULATION SYSTEM FOR TREATING LYSOSOMAL DISEASES, AND METHODS OF TREATING LYSOSOMAL DISEASES |
| WO2019193183A2 (en) | 2018-04-05 | 2019-10-10 | Curevac Ag | Novel yellow fever nucleic acid molecules for vaccination |
| EP4142802A4 (en) * | 2020-04-28 | 2024-07-24 | The Trustees of The University of Pennsylvania | COMPOSITIONS AND USES THEREOF FOR THE TREATMENT OF ANGELMAN SYNDROME |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US4929555A (en) | 1987-10-19 | 1990-05-29 | Phillips Petroleum Company | Pichia transformation |
| US20020123476A1 (en) | 1991-03-19 | 2002-09-05 | Emanuele R. Martin | Therapeutic delivery compositions and methods of use thereof |
| US5587308A (en) | 1992-06-02 | 1996-12-24 | The United States Of America As Represented By The Department Of Health & Human Services | Modified adeno-associated virus vector capable of expression from a novel promoter |
| US6806084B1 (en) | 1992-06-04 | 2004-10-19 | The Regents Of The University Of California | Methods for compositions for in vivo gene delivery |
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| AU2887897A (en) | 1996-05-21 | 1997-12-09 | Novo Nordisk A/S | Novel yeast promoters suitable for expression cloning in yeast and heterologous expression of proteins in yeast |
| US20060014264A1 (en) | 2004-07-13 | 2006-01-19 | Stowers Institute For Medical Research | Cre/lox system with lox sites having an extended spacer region |
| WO2006129080A1 (en) | 2005-05-31 | 2006-12-07 | The Institute Of Cancer Research: Royal Cancer Hospital | Materials and methods for transducing cells with a viral vector |
| AU2006316122A1 (en) | 2005-11-18 | 2007-05-24 | Altif Laboratories Inc. | Novel highly functional enzyme having modified substrate-specificity |
| KR20170091174A (ko) | 2007-04-03 | 2017-08-08 | 옥시레인 유케이 리미티드 | 분자의 글리코실화 |
| WO2008143354A1 (ja) | 2007-05-18 | 2008-11-27 | Tokyo Metropolitan Organization For Medical Research | 酵素補充療法用医薬組成物 |
| ES2783024T3 (es) | 2009-09-29 | 2020-09-16 | Univ Gent | Hidrólisis de la unión de manosa-1-fosfo-6-manosa a fosfo-6-manosa |
| CN103328646B (zh) | 2010-09-29 | 2021-06-18 | 奥克西雷恩英国有限公司 | 能够使甘露糖-1-磷酸-6-甘露糖连接脱帽并使磷酸化的n-聚糖脱甘露糖基化的甘露糖苷酶及促进糖蛋白的哺乳动物细胞摄取的方法 |
| KR20190114003A (ko) | 2012-03-15 | 2019-10-08 | 옥시레인 유케이 리미티드 | 폼페병의 치료를 위한 방법 및 물질 |
| KR102702200B1 (ko) | 2014-12-22 | 2024-09-02 | 코덱시스, 인코포레이티드 | 인간 알파-갈락토시다제 변이체 |
| EP3393501B1 (en) * | 2015-12-24 | 2023-06-07 | Oxyrane UK Limited | Human alpha-n-acetylgalactosaminidase polypeptide |
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- 2016-12-22 EP EP16831567.9A patent/EP3393501B1/en active Active
- 2016-12-22 KR KR1020187021246A patent/KR20180088919A/ko not_active Abandoned
- 2016-12-22 US US16/063,408 patent/US11040114B2/en not_active Expired - Fee Related
- 2016-12-22 WO PCT/EP2016/082304 patent/WO2017109034A1/en not_active Ceased
- 2016-12-22 JP JP2018532655A patent/JP6956417B2/ja not_active Expired - Fee Related
- 2016-12-22 CA CA3008975A patent/CA3008975A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11040114B2 (en) | 2021-06-22 |
| US20180360991A1 (en) | 2018-12-20 |
| EP3393501B1 (en) | 2023-06-07 |
| KR20180088919A (ko) | 2018-08-07 |
| EP3393501A1 (en) | 2018-10-31 |
| JP6956417B2 (ja) | 2021-11-02 |
| WO2017109034A1 (en) | 2017-06-29 |
| EP3393501C0 (en) | 2023-06-07 |
| JP2019503171A (ja) | 2019-02-07 |
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