CA3005131A1 - Antisense oligomers for treatment of tuberous sclerosis complex - Google Patents
Antisense oligomers for treatment of tuberous sclerosis complex Download PDFInfo
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- CA3005131A1 CA3005131A1 CA3005131A CA3005131A CA3005131A1 CA 3005131 A1 CA3005131 A1 CA 3005131A1 CA 3005131 A CA3005131 A CA 3005131A CA 3005131 A CA3005131 A CA 3005131A CA 3005131 A1 CA3005131 A1 CA 3005131A1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201562267212P | 2015-12-14 | 2015-12-14 | |
| US62/267,212 | 2015-12-14 | ||
| PCT/US2016/066705 WO2017106375A1 (en) | 2015-12-14 | 2016-12-14 | Antisense oligomers for treatment of tuberous sclerosis complex |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3005131A1 true CA3005131A1 (en) | 2017-06-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3005131A Pending CA3005131A1 (en) | 2015-12-14 | 2016-12-14 | Antisense oligomers for treatment of tuberous sclerosis complex |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3390635A4 (enExample) |
| JP (2) | JP7051683B2 (enExample) |
| CA (1) | CA3005131A1 (enExample) |
| WO (1) | WO2017106375A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| EP3201339A4 (en) | 2014-10-03 | 2018-09-19 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| EP3359685A1 (en) | 2015-10-09 | 2018-08-15 | University Of Southampton | Modulation of gene expression and screening for deregulated protein expression |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| KR102604132B1 (ko) | 2015-12-14 | 2023-11-17 | 콜드스프링하버러보러토리 | 상염색체 우성 정신 지체 5 및 드라베 증후군의 치료를 위한 안티센스 올리고머 |
| KR102712656B1 (ko) | 2017-01-23 | 2024-10-04 | 리제너론 파마슈티칼스 인코포레이티드 | Hsd17b13 변종 및 이것의 용도 |
| US11479802B2 (en) | 2017-04-11 | 2022-10-25 | Regeneron Pharmaceuticals, Inc. | Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family |
| SI3673080T1 (sl) | 2017-08-25 | 2024-03-29 | Stoke Therapeutics, Inc. | Protismiselni oligomeri za zdravljenje bolezenskih stanj in bolezni |
| AU2018348195B2 (en) | 2017-10-11 | 2025-05-15 | Regeneron Pharmaceuticals, Inc. | Inhibition of HSD17B13 in the treatment of liver disease in patients expressing the PNPLA3 I148M variation |
| BR112020018758A2 (pt) | 2018-03-21 | 2021-01-26 | Regeneron Pharmaceuticals, Inc. | agente de ácido ribonucleico de fita dupla, célula, vetor, composição farmacêutica, e, métodos para inibição da expressão de 17¿-hidroxiesteroide desidrogenases tipo 13, para tratamento de um indivíduo, para prevenção de um sintoma em um indivíduo, para redução do risco de desenvolver doença hepática crônica, para inibição da progressão de esteatose, para inibição do acúmulo de gotículas de lipídios |
| BR112020022512A2 (pt) | 2018-05-04 | 2021-05-04 | Stoke Therapeutics, Inc. | métodos e composições para tratamento de doença de armazenamento de éster de colesteril |
| CN114746550A (zh) * | 2019-08-19 | 2022-07-12 | 斯托克制药公司 | 用于调节剪接和蛋白质表达的组合物和方法 |
| AU2021270720A1 (en) | 2020-05-11 | 2022-12-08 | Stoke Therapeutics, Inc. | OPA1 antisense oligomers for treatment of conditions and diseases |
| EP4560019A1 (en) * | 2023-11-22 | 2025-05-28 | Sylentis S.A.U. | Sirna and compositions for prophylactic and therapeutic treatment of ocular retinal conditions |
| EP4560020A1 (en) * | 2023-11-22 | 2025-05-28 | Sylentis S.A.U. | Sirna and compositions for prophylactic and therapeutic treatment of ocular retinal conditions |
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| WO2008043561A2 (en) * | 2006-10-11 | 2008-04-17 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Influenza targets |
| WO2011020118A1 (en) | 2009-08-14 | 2011-02-17 | Theramind Research, Llc | Methods and compositions for treatment of tuberous sclerosis complex |
| CA2773049C (en) * | 2009-09-08 | 2019-08-20 | Laboratory Corporation Of America Holdings | Compositions and methods for diagnosing autism spectrum disorders |
| CA2930859C (en) * | 2013-09-04 | 2022-05-03 | Cold Spring Harbor Laboratory | Reducing nonsense-mediated mrna decay |
| GB201410693D0 (en) * | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| EP3201339A4 (en) * | 2014-10-03 | 2018-09-19 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| JP7049249B2 (ja) * | 2015-12-14 | 2022-04-06 | コールド スプリング ハーバー ラボラトリー | 中枢神経系疾患の処置のための組成物および方法 |
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2016
- 2016-12-14 CA CA3005131A patent/CA3005131A1/en active Pending
- 2016-12-14 WO PCT/US2016/066705 patent/WO2017106375A1/en not_active Ceased
- 2016-12-14 EP EP16876615.2A patent/EP3390635A4/en not_active Withdrawn
- 2016-12-14 JP JP2018529258A patent/JP7051683B2/ja active Active
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2022
- 2022-03-29 JP JP2022053948A patent/JP2022088533A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017106375A1 (en) | 2017-06-22 |
| JP2022088533A (ja) | 2022-06-14 |
| EP3390635A4 (en) | 2019-05-01 |
| JP2019500350A (ja) | 2019-01-10 |
| EP3390635A1 (en) | 2018-10-24 |
| JP7051683B2 (ja) | 2022-04-11 |
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