CA3003262C - Spexin-based galanin receptor type 2 agonists and use thereof - Google Patents
Spexin-based galanin receptor type 2 agonists and use thereof Download PDFInfo
- Publication number
- CA3003262C CA3003262C CA3003262A CA3003262A CA3003262C CA 3003262 C CA3003262 C CA 3003262C CA 3003262 A CA3003262 A CA 3003262A CA 3003262 A CA3003262 A CA 3003262A CA 3003262 C CA3003262 C CA 3003262C
- Authority
- CA
- Canada
- Prior art keywords
- seq
- amino acid
- galr2
- acid sequence
- set forth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2015-0168555 | 2015-11-30 | ||
KR1020150168555A KR101885238B1 (ko) | 2015-11-30 | 2015-11-30 | 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도 |
PCT/KR2016/013950 WO2017095132A1 (ko) | 2015-11-30 | 2016-11-30 | 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA3003262A1 CA3003262A1 (en) | 2017-06-08 |
CA3003262C true CA3003262C (en) | 2023-10-31 |
Family
ID=58797220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3003262A Active CA3003262C (en) | 2015-11-30 | 2016-11-30 | Spexin-based galanin receptor type 2 agonists and use thereof |
Country Status (9)
Country | Link |
---|---|
US (3) | US10385098B2 (ko) |
EP (1) | EP3384920A4 (ko) |
JP (1) | JP6619097B2 (ko) |
KR (1) | KR101885238B1 (ko) |
CN (1) | CN108348570B (ko) |
AU (2) | AU2016361783C1 (ko) |
BR (1) | BR112018008315A2 (ko) |
CA (1) | CA3003262C (ko) |
WO (1) | WO2017095132A1 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6022287A (en) | 1998-08-19 | 2000-02-08 | General Motors Corporation | Modularly constructed vehicular transmission |
KR101885238B1 (ko) | 2015-11-30 | 2018-08-06 | 주식회사 뉴라클사이언스 | 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도 |
EP3645040A4 (en) | 2017-06-27 | 2021-05-05 | Neuracle Science Co., Ltd | USE OF ANTI-FAM19A5 ANTIBODIES FOR THE TREATMENT OF CANCERS |
CN111154712B (zh) * | 2020-01-10 | 2022-02-08 | 复旦大学附属华山医院 | 一种Spexin促进胰岛素的分泌和胰岛细胞增殖的方法 |
CN116751261B (zh) * | 2023-06-29 | 2024-05-14 | 湖南中晟全肽生物科技股份有限公司 | 一种galr2激动剂及其应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5972624A (en) * | 1996-01-24 | 1999-10-26 | Synaptic Pharmaceutical Corporation | Method of identifying ligands which bind recombinant galanin receptor (GALR2) |
GB0403509D0 (en) * | 2004-02-17 | 2004-03-24 | Neuro Targets Ltd | Galanin receptors and brain injury |
EP1978987B1 (en) * | 2006-01-05 | 2014-12-31 | University of Utah Research Foundation | Methods and compositions related to improving properties of pharmacological agents targeting nervous system |
EP2622351B1 (en) | 2010-09-28 | 2014-08-27 | Actelion Pharmaceuticals Ltd. | Neuropeptide q as modulator of gpcr galr2 and uses thereof |
WO2012051567A2 (en) * | 2010-10-15 | 2012-04-19 | The Trustees Of Columbia University In The City Of New York | Obesity-related genes and their proteins and uses thereof |
WO2012051657A1 (en) | 2010-10-20 | 2012-04-26 | Poolrite Research Pty Ltd | Method for water sanitisation |
US9556242B2 (en) | 2011-01-24 | 2017-01-31 | Anygen Co., Ltd. | Method for regulating circadian rhythms |
KR101885238B1 (ko) | 2015-11-30 | 2018-08-06 | 주식회사 뉴라클사이언스 | 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도 |
-
2015
- 2015-11-30 KR KR1020150168555A patent/KR101885238B1/ko active IP Right Grant
-
2016
- 2016-11-30 JP JP2018523789A patent/JP6619097B2/ja active Active
- 2016-11-30 AU AU2016361783A patent/AU2016361783C1/en active Active
- 2016-11-30 WO PCT/KR2016/013950 patent/WO2017095132A1/ko active Application Filing
- 2016-11-30 CA CA3003262A patent/CA3003262C/en active Active
- 2016-11-30 CN CN201680062527.4A patent/CN108348570B/zh active Active
- 2016-11-30 BR BR112018008315-1A patent/BR112018008315A2/ko active Search and Examination
- 2016-11-30 EP EP16871028.3A patent/EP3384920A4/en active Pending
- 2016-11-30 US US15/771,078 patent/US10385098B2/en active Active
-
2019
- 2019-04-26 AU AU2019202918A patent/AU2019202918B2/en active Active
- 2019-07-15 US US16/511,976 patent/US11248023B2/en active Active
-
2022
- 2022-01-19 US US17/579,463 patent/US20220242910A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US11248023B2 (en) | 2022-02-15 |
CA3003262A1 (en) | 2017-06-08 |
US20200010509A1 (en) | 2020-01-09 |
US20220242910A1 (en) | 2022-08-04 |
US10385098B2 (en) | 2019-08-20 |
KR20170062848A (ko) | 2017-06-08 |
WO2017095132A1 (ko) | 2017-06-08 |
AU2019202918B2 (en) | 2020-04-30 |
AU2019202918A1 (en) | 2019-05-16 |
EP3384920A4 (en) | 2019-05-08 |
EP3384920A1 (en) | 2018-10-10 |
AU2016361783C1 (en) | 2019-06-06 |
JP6619097B2 (ja) | 2019-12-11 |
CN108348570A (zh) | 2018-07-31 |
KR101885238B1 (ko) | 2018-08-06 |
CN108348570B (zh) | 2022-05-03 |
US20180319841A1 (en) | 2018-11-08 |
BR112018008315A2 (ko) | 2018-10-30 |
AU2016361783A1 (en) | 2018-05-10 |
AU2016361783B2 (en) | 2019-02-07 |
JP2018537444A (ja) | 2018-12-20 |
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Legal Events
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EEER | Examination request |
Effective date: 20180425 |
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EEER | Examination request |
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EEER | Examination request |
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