CA2998091A1 - Method for producing retinal tissue - Google Patents

Method for producing retinal tissue Download PDF

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Publication number
CA2998091A1
CA2998091A1 CA2998091A CA2998091A CA2998091A1 CA 2998091 A1 CA2998091 A1 CA 2998091A1 CA 2998091 A CA2998091 A CA 2998091A CA 2998091 A CA2998091 A CA 2998091A CA 2998091 A1 CA2998091 A1 CA 2998091A1
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Prior art keywords
cell
cells
retinal
medium
production method
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CA2998091A
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English (en)
French (fr)
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CA2998091C (en
Inventor
Satoshi Ando
Takao Kuroda
Yoshiki Sasai (Deceased)
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Sumitomo Chemical Co Ltd
RIKEN Institute of Physical and Chemical Research
Sumitomo Pharma Co Ltd
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Sumitomo Dainippon Pharma Co Ltd
Sumitomo Chemical Co Ltd
RIKEN Institute of Physical and Chemical Research
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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0621Eye cells, e.g. cornea, iris pigmented cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • CCHEMISTRY; METALLURGY
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5058Neurological cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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    • C12N2513/003D culture

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  • General Engineering & Computer Science (AREA)
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  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
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CA2998091A 2015-09-08 2016-09-08 Method for producing retinal tissue Active CA2998091C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015176897 2015-09-08
JP2015-176897 2015-09-08
PCT/JP2016/076523 WO2017043604A1 (ja) 2015-09-08 2016-09-08 網膜組織の製造方法

Publications (2)

Publication Number Publication Date
CA2998091A1 true CA2998091A1 (en) 2017-03-16
CA2998091C CA2998091C (en) 2024-06-11

Family

ID=58240839

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2998091A Active CA2998091C (en) 2015-09-08 2016-09-08 Method for producing retinal tissue

Country Status (6)

Country Link
US (1) US20180245039A1 (ja)
EP (1) EP3348631B1 (ja)
JP (2) JP6884354B2 (ja)
CA (1) CA2998091C (ja)
ES (1) ES2971677T3 (ja)
WO (1) WO2017043604A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112831461A (zh) * 2021-02-26 2021-05-25 澳门大学 一种诱导干细胞分化成中胚层谱系或滋养细胞谱系的方法及药物

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
CA2965248A1 (en) 2014-10-24 2016-04-28 Sumitomo Dainippon Pharma Co., Ltd. Production method for nerve tissue
MY183058A (en) 2014-10-24 2021-02-09 Riken Production method for retinal tissue
WO2017183732A1 (ja) * 2016-04-22 2017-10-26 大日本住友製薬株式会社 網膜組織の製造法
CN111094554A (zh) * 2017-09-14 2020-05-01 国立研究开发法人理化学研究所 视网膜组织的制备方法
US20210071137A1 (en) * 2017-11-24 2021-03-11 Sumitomo Chemical Company, Limited Production method for cell mass including neural cells/tissue and non-neural epithelial tissue, and cell mass from same
CA3086765A1 (en) 2017-12-28 2019-07-04 Tract Pharmaceuticals, Inc. Stem cell culture systems for columnar epithelial stem cells, and uses related thereto
JPWO2022138803A1 (ja) * 2020-12-24 2022-06-30
CN114717178A (zh) * 2022-03-03 2022-07-08 中国医学科学院医学生物学研究所 一种树鼩睾丸间质细胞的分离培养方法及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3640326A1 (en) * 2007-04-18 2020-04-22 Hadasit Medical Research Services & Development Limited Stem cell-derived retinal pigment epithelial cells
EP2401364B1 (en) * 2009-02-27 2015-04-22 Cellular Dynamics International, Inc. Differentiation of pluripotent cells
KR102160721B1 (ko) * 2010-12-22 2020-09-29 페이트 세러퓨틱스, 인코포레이티드 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼
CA3114895A1 (en) * 2011-11-25 2013-05-30 Sumitomo Chemical Company, Limited Artificial cell aggregate comprising retinal tissue
EP3323884A1 (en) * 2013-02-01 2018-05-23 The United States Of America as Represented by the Secretary, Department of Health an Human Service Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
KR102278978B1 (ko) * 2013-08-23 2021-07-19 스미또모 가가꾸 가부시끼가이샤 망막 조직 및 망막 관련 세포의 제조 방법
WO2015068505A1 (ja) * 2013-11-11 2015-05-14 住友化学株式会社 網膜色素上皮細胞の製造方法
KR102368751B1 (ko) * 2014-01-17 2022-03-03 스미또모 가가꾸 가부시끼가이샤 모양체 주연부 간세포의 제조 방법
US20170198260A1 (en) * 2014-05-23 2017-07-13 The University Of Tokyo Method for producing mesothelial cells and a cell sheet for preventing adhesion
CA2965248A1 (en) * 2014-10-24 2016-04-28 Sumitomo Dainippon Pharma Co., Ltd. Production method for nerve tissue
MY183058A (en) * 2014-10-24 2021-02-09 Riken Production method for retinal tissue

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112831461A (zh) * 2021-02-26 2021-05-25 澳门大学 一种诱导干细胞分化成中胚层谱系或滋养细胞谱系的方法及药物
CN112831461B (zh) * 2021-02-26 2023-08-08 澳门大学 一种诱导干细胞分化成中胚层谱系或滋养细胞谱系的方法及药物

Also Published As

Publication number Publication date
CA2998091C (en) 2024-06-11
JP7154546B2 (ja) 2022-10-18
ES2971677T3 (es) 2024-06-06
WO2017043604A1 (ja) 2017-03-16
EP3348631B1 (en) 2023-11-29
EP3348631A1 (en) 2018-07-18
US20180245039A1 (en) 2018-08-30
EP3348631A4 (en) 2019-03-06
JP6884354B2 (ja) 2021-06-09
JP2021118733A (ja) 2021-08-12
JPWO2017043604A1 (ja) 2018-06-28

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