CA2993215C - Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device - Google Patents
Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device Download PDFInfo
- Publication number
- CA2993215C CA2993215C CA2993215A CA2993215A CA2993215C CA 2993215 C CA2993215 C CA 2993215C CA 2993215 A CA2993215 A CA 2993215A CA 2993215 A CA2993215 A CA 2993215A CA 2993215 C CA2993215 C CA 2993215C
- Authority
- CA
- Canada
- Prior art keywords
- preparation
- delivery
- capsule
- tissue penetrating
- insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229940124597 therapeutic agent Drugs 0.000 title abstract description 99
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract description 92
- 238000012377 drug delivery Methods 0.000 title description 42
- 239000002775 capsule Substances 0.000 claims abstract description 194
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562188408P | 2015-07-02 | 2015-07-02 | |
| US62/188,408 | 2015-07-02 | ||
| PCT/US2016/041013 WO2017004623A1 (en) | 2015-07-02 | 2016-07-05 | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2993215A1 CA2993215A1 (en) | 2017-01-05 |
| CA2993215C true CA2993215C (en) | 2023-10-31 |
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| CA2993215A Active CA2993215C (en) | 2015-07-02 | 2016-07-05 | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
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| Country | Link |
|---|---|
| EP (1) | EP3316872A4 (enExample) |
| JP (2) | JP2018519313A (enExample) |
| CN (1) | CN108055826A (enExample) |
| AU (1) | AU2016287843B2 (enExample) |
| CA (1) | CA2993215C (enExample) |
| WO (1) | WO2017004623A1 (enExample) |
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| WO2011017335A1 (en) | 2009-08-03 | 2011-02-10 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
| US8721620B2 (en) | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
| US11369574B2 (en) | 2017-05-17 | 2022-06-28 | Massachusetts Institute Of Technology | Self-righting systems and related components and methods |
| TWI797133B (zh) * | 2017-06-09 | 2023-04-01 | 丹麥商諾佛 儂迪克股份有限公司 | 用於經口投予的固體組成物 |
| AU2019269636A1 (en) | 2018-05-17 | 2020-11-19 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
| AU2019321648A1 (en) * | 2018-08-15 | 2021-03-18 | Lyndra Therapeutics, Inc. | Systems for enteric delivery of therapeutic agents |
| CN113543756B (zh) * | 2018-12-31 | 2023-09-05 | 拉尼医疗有限公司 | 使用可吞服药物递送装置递送到肠道内腔的治疗剂制剂 |
| JP2022523121A (ja) | 2019-02-01 | 2022-04-21 | マサチューセッツ インスティテュート オブ テクノロジー | 液体注入のためのシステムおよび方法 |
| BR112021017993A2 (pt) * | 2019-03-13 | 2022-01-18 | Rani Therapeutics Llc | Preparações de agente terapêutico e métodos para liberação de fármacos em um lúmen do trato intestinal com o uso de um dispositivo ingerível de liberação de fármacos |
| US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
| EP4106854A4 (en) * | 2020-02-18 | 2024-04-03 | Rani Therapeutics, LLC | INJECTION OF A THERAPEUTIC FORMULATION INTO A WALL OF THE GASTRO-NTESTINAL TRACT |
| US11372392B2 (en) | 2020-09-18 | 2022-06-28 | International Business Machines Corporation | System and method of printing 3D biostructures |
| WO2024209050A1 (en) | 2023-04-05 | 2024-10-10 | Antag Therapeutics Aps | Gip activity modulators and orthostatic intolerance |
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| US5652216A (en) * | 1994-05-26 | 1997-07-29 | Novo Nordisk A/S | Pharmaceutical preparation |
| DE60045030D1 (de) * | 1999-02-10 | 2010-11-11 | Curis Inc | Peptid yy (pyy) zur behandlung von glukose stoffwechselkrankheiten |
| US9399054B2 (en) * | 2004-07-12 | 2016-07-26 | Emisphere Technologies, Inc. | Compositions for delivering peptide YY and PYY agonists |
| US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
| PE20091730A1 (es) * | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| WO2010045656A2 (en) * | 2008-10-17 | 2010-04-22 | Nectid, Inc. | Novel sglt2 inhibitor dosage forms |
| US8721620B2 (en) * | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
| WO2012035559A2 (en) * | 2010-09-17 | 2012-03-22 | Panacea Biotec Ltd | Sustained release pharmaceutical compositions comprising pregabalin |
| US8809269B2 (en) * | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402807B2 (en) * | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| WO2013003824A1 (en) * | 2011-06-29 | 2013-01-03 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
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2016
- 2016-07-05 CA CA2993215A patent/CA2993215C/en active Active
- 2016-07-05 JP JP2017567700A patent/JP2018519313A/ja not_active Withdrawn
- 2016-07-05 EP EP16818960.3A patent/EP3316872A4/en not_active Withdrawn
- 2016-07-05 WO PCT/US2016/041013 patent/WO2017004623A1/en not_active Ceased
- 2016-07-05 AU AU2016287843A patent/AU2016287843B2/en active Active
- 2016-07-05 CN CN201680050621.8A patent/CN108055826A/zh active Pending
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2020
- 2020-08-06 JP JP2020133753A patent/JP2020176152A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016287843A1 (en) | 2018-01-18 |
| CA2993215A1 (en) | 2017-01-05 |
| AU2016287843B2 (en) | 2021-06-17 |
| EP3316872A4 (en) | 2018-12-26 |
| JP2018519313A (ja) | 2018-07-19 |
| WO2017004623A1 (en) | 2017-01-05 |
| CN108055826A (zh) | 2018-05-18 |
| JP2020176152A (ja) | 2020-10-29 |
| EP3316872A1 (en) | 2018-05-09 |
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