CA2986766A1 - Immune tolerant and non-immune tolerant elastin-like recombinant peptides and methods of use - Google Patents
Immune tolerant and non-immune tolerant elastin-like recombinant peptides and methods of useInfo
- Publication number
- CA2986766A1 CA2986766A1 CA2986766A CA2986766A CA2986766A1 CA 2986766 A1 CA2986766 A1 CA 2986766A1 CA 2986766 A CA2986766 A CA 2986766A CA 2986766 A CA2986766 A CA 2986766A CA 2986766 A1 CA2986766 A1 CA 2986766A1
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- CA
- Canada
- Prior art keywords
- gly
- val
- seq
- pro
- leu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- A61P35/04—Antineoplastic agents specific for metastasis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/77—Ovalbumin
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- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Zoology (AREA)
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- Oncology (AREA)
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- Mycology (AREA)
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- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US201562230160P | 2015-05-29 | 2015-05-29 | |
| US62/230,160 | 2015-05-29 | ||
| US201662309113P | 2016-03-16 | 2016-03-16 | |
| US62/309,113 | 2016-03-16 | ||
| PCT/US2016/034530 WO2016196249A1 (en) | 2015-05-29 | 2016-05-27 | Immune tolerant and non-immune tolerant elastin-like recombinant peptides and methods of use |
Publications (1)
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| CA2986766A1 true CA2986766A1 (en) | 2016-12-08 |
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| CA2986766A Pending CA2986766A1 (en) | 2015-05-29 | 2016-05-27 | Immune tolerant and non-immune tolerant elastin-like recombinant peptides and methods of use |
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| US (1) | US11957762B2 (enExample) |
| EP (1) | EP3302531B1 (enExample) |
| JP (1) | JP6924151B2 (enExample) |
| CN (1) | CN107750163A (enExample) |
| CA (1) | CA2986766A1 (enExample) |
| WO (1) | WO2016196249A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US11198722B2 (en) | 2017-10-06 | 2021-12-14 | University Of Utah Research Foundation | Immune tolerant elastin-like peptide tetramer guided nanoparticles and methods of use |
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| WO2020048996A1 (en) | 2018-09-06 | 2020-03-12 | ETH Zürich | Self-assembling globular proteins and uses thereof |
| CN111346235A (zh) * | 2018-12-20 | 2020-06-30 | 海南医学院第一附属医院 | 一种基于弹性靶向多肽的载药纳米颗粒及其制备方法和应用 |
| MX2022002293A (es) * | 2019-08-23 | 2022-06-02 | Univ Utah Res Found | Péptidos recombinantes inmunotolerantes similares a la elastina y métodos de uso. |
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| US4703004A (en) | 1984-01-24 | 1987-10-27 | Immunex Corporation | Synthesis of protein with an identification peptide |
| US4851341A (en) | 1986-12-19 | 1989-07-25 | Immunex Corporation | Immunoaffinity purification system |
| US5206353A (en) | 1988-07-23 | 1993-04-27 | The United States Of America As Represented By The Department Of Health And Human Services | CD-4/cytotoxic gene fusions |
| WO1994012520A1 (en) | 1992-11-20 | 1994-06-09 | Enzon, Inc. | Linker for linked fusion polypeptides |
| US5914254A (en) | 1993-08-02 | 1999-06-22 | Celtrix Pharmaceuticals, Inc. | Expression of fusion polypeptides transported out of the cytoplasm without leader sequences |
| US5763733A (en) | 1994-10-13 | 1998-06-09 | Enzon, Inc. | Antigen-binding fusion proteins |
| US5981177A (en) | 1995-01-25 | 1999-11-09 | Demirjian; David C. | Protein fusion method and constructs |
| US5994104A (en) | 1996-11-08 | 1999-11-30 | Royal Free Hospital School Of Medicine | Interleukin-12 fusion protein |
| WO1998022577A1 (en) | 1996-11-15 | 1998-05-28 | Maria Grazia Masucci | Fusion proteins having increased half-lives |
| WO1998036087A1 (en) | 1997-02-13 | 1998-08-20 | American National Red Cross | Immunological tolerance to hiv epitopes |
| US7494788B2 (en) * | 2005-07-11 | 2009-02-24 | Molecular Kinetics, Inc. | Entropic bristle domain sequences and their use in recombinant protein production |
| US8470967B2 (en) * | 2010-09-24 | 2013-06-25 | Duke University | Phase transition biopolymers and methods of use |
| US9114128B2 (en) * | 2011-09-30 | 2015-08-25 | Protein Genomics, Inc. | Tropoelastins and uses thereof |
| EP3052125B1 (en) * | 2013-10-01 | 2020-09-30 | University of Mississippi Medical Center | Elastin-like polypeptide coupled to therapeutic agent for delivery during pregnancy |
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- 2016-05-27 WO PCT/US2016/034530 patent/WO2016196249A1/en not_active Ceased
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11198722B2 (en) | 2017-10-06 | 2021-12-14 | University Of Utah Research Foundation | Immune tolerant elastin-like peptide tetramer guided nanoparticles and methods of use |
| US12162923B2 (en) | 2017-10-06 | 2024-12-10 | Univeristy Of Utah Research Foundation | Immune tolerant elastin-like peptide tetramer guided nanoparticles and methods of use |
Also Published As
| Publication number | Publication date |
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| WO2016196249A1 (en) | 2016-12-08 |
| US11957762B2 (en) | 2024-04-16 |
| EP3302531B1 (en) | 2021-02-17 |
| CN107750163A (zh) | 2018-03-02 |
| EP3302531A4 (en) | 2019-02-20 |
| JP2018521977A (ja) | 2018-08-09 |
| US20180289830A1 (en) | 2018-10-11 |
| EP3302531A1 (en) | 2018-04-11 |
| JP6924151B2 (ja) | 2021-08-25 |
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