CA2979413C - Compositions for the treatment of fibrosis and fibrosis-related conditions - Google Patents

Compositions for the treatment of fibrosis and fibrosis-related conditions Download PDF

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CA2979413C
CA2979413C CA2979413A CA2979413A CA2979413C CA 2979413 C CA2979413 C CA 2979413C CA 2979413 A CA2979413 A CA 2979413A CA 2979413 A CA2979413 A CA 2979413A CA 2979413 C CA2979413 C CA 2979413C
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compound
fibrosis
optionally substituted
6alkyl
compound according
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French (fr)
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CA2979413A1 (en
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Karen Annette Duggan
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Vectus Biosystems Ltd
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Vectus Biosystems Ltd
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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
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    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms

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IL254505A0 (en) 2017-11-30
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NZ736164A (en) 2022-07-01
RU2712140C2 (ru) 2020-01-24
US10035775B2 (en) 2018-07-31
EP3271320A4 (en) 2018-11-14
CN107531598A (zh) 2018-01-02
MY182818A (en) 2021-02-05
RU2017135950A3 (da) 2019-08-16
ES2766769T3 (es) 2020-06-15
AU2016232978B2 (en) 2019-05-02
BR112017019824A2 (pt) 2018-05-29
WO2016145479A1 (en) 2016-09-22
AU2016232978A1 (en) 2017-10-26
BR112017019824B1 (pt) 2023-02-23
CN107531598B (zh) 2020-10-16
EP3271320A1 (en) 2018-01-24
ZA201706985B (en) 2019-04-24
KR102591689B1 (ko) 2023-10-18
EP3271320B1 (en) 2019-10-23
JP6734294B2 (ja) 2020-08-05
CA2979413A1 (en) 2016-09-22
RU2017135950A (ru) 2019-04-18
US20180072682A1 (en) 2018-03-15

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