CA2964310C - Reactance and capacitance sensing platform for detecting microorganisms - Google Patents

Reactance and capacitance sensing platform for detecting microorganisms Download PDF

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Publication number
CA2964310C
CA2964310C CA2964310A CA2964310A CA2964310C CA 2964310 C CA2964310 C CA 2964310C CA 2964310 A CA2964310 A CA 2964310A CA 2964310 A CA2964310 A CA 2964310A CA 2964310 C CA2964310 C CA 2964310C
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Canada
Prior art keywords
sample
impedance
khz
electrodes
vessel
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CA2964310A
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English (en)
French (fr)
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CA2964310A1 (en
Inventor
Patrick Shawn Beaty
Michael A. Brasch
Suneil HOSMANE
David Polley
Julie L. Rosales
Kerry Lynn Smith
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Becton Dickinson and Co
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Becton Dickinson and Co
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Publication of CA2964310A1 publication Critical patent/CA2964310A1/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48785Electrical and electronic details of measuring devices for physical analysis of liquid biological material not specific to a particular test method, e.g. user interface or power supply
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026Dielectric impedance spectroscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Human Computer Interaction (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2964310A 2014-10-14 2015-10-14 Reactance and capacitance sensing platform for detecting microorganisms Active CA2964310C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462063602P 2014-10-14 2014-10-14
US62/063,602 2014-10-14
PCT/US2015/055501 WO2016064635A1 (en) 2014-10-14 2015-10-14 Reactance and capacitance sensing platform for detecting microorganisms

Publications (2)

Publication Number Publication Date
CA2964310A1 CA2964310A1 (en) 2016-04-28
CA2964310C true CA2964310C (en) 2019-02-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2964310A Active CA2964310C (en) 2014-10-14 2015-10-14 Reactance and capacitance sensing platform for detecting microorganisms

Country Status (8)

Country Link
US (2) US10808217B2 (enExample)
EP (1) EP3207362B1 (enExample)
JP (1) JP6795495B2 (enExample)
CN (3) CN107110803A (enExample)
AU (1) AU2015336363B2 (enExample)
CA (1) CA2964310C (enExample)
ES (1) ES2982089T3 (enExample)
WO (1) WO2016064635A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
JP6795495B2 (ja) 2014-10-14 2020-12-02 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 微生物を検出するリアクタンス及びキャパシタンス検知プラットフォーム
KR102461735B1 (ko) * 2016-09-23 2022-11-01 알베오 테크놀로지스 인크. 분석물을 검출하기 위한 방법 및 조성물
WO2019147225A1 (en) * 2018-01-24 2019-08-01 Hewlett-Packard Development Company, L.P. Fluidic property determination from fluid impedances
US20190241861A1 (en) * 2018-02-02 2019-08-08 Karmel Alon Allison Bacterial detection system
AU2019401601A1 (en) 2018-12-20 2021-07-15 Alveo Technologies, Inc. Handheld impedance-based diagnostic test system for detecting analytes
US12472492B2 (en) 2020-08-14 2025-11-18 Alveo Technologies, Inc. Systems and methods of sample depositing and testing
CN113406153B (zh) * 2021-06-29 2022-06-07 毕玉琦 一种食品菌群快速检测装置
US12474250B2 (en) * 2023-06-27 2025-11-18 International Business Machines Corporation Linear fluidic cell trap device for single cell detection

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW418323B (en) * 1998-02-19 2001-01-11 Sumitomo Metal Ind Capacitance detection system and method
EP1117995A1 (en) * 1998-10-09 2001-07-25 Simon Feldberg Method and apparatus for determining and evaluating bacterial populations
EP1162449A1 (en) * 2000-06-06 2001-12-12 Universiteit Gent AC-based gate detection method and device for the sizing of colloidal particles, cells and bacteria in liquids
US6649402B2 (en) 2001-06-22 2003-11-18 Wisconsin Alumni Research Foundation Microfabricated microbial growth assay method and apparatus
US6433560B1 (en) * 2001-08-31 2002-08-13 Eaton Corporation Combined fluid condition monitor and fluid level sensor
JP2008519275A (ja) * 2004-11-05 2008-06-05 グレーストン・ファイナンス・エスエー 生物学的な、バイオアクティブな、バイオエナジェティックな及びバイオハーモニックな信号を検出、測定及び分析するための方法及び装置
US8318099B2 (en) 2005-10-26 2012-11-27 General Electric Company Chemical and biological sensors, systems and methods based on radio frequency identification
US7923241B2 (en) * 2007-10-10 2011-04-12 Corning Incorporated Cell culture article and methods thereof
US10094818B2 (en) * 2008-05-07 2018-10-09 University Of Strathclyde Bacterial/cellular recognition impedance algorithm
CN101698879A (zh) * 2009-10-14 2010-04-28 电子科技大学 检测细菌培养基电阻抗曲线形态的药物敏感试验方法
TW201226896A (en) * 2010-12-17 2012-07-01 Univ Yuanpei Microbe or cell inspection system and method thereof
CN102954985A (zh) * 2011-08-31 2013-03-06 中国科学院上海微系统与信息技术研究所 一种电阻抗式细菌快速检测传感器的数据分析方法
WO2013123189A1 (en) * 2012-02-15 2013-08-22 Becton, Dickinson And Company Impedence-based bacterial detection system
JP6795495B2 (ja) 2014-10-14 2020-12-02 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 微生物を検出するリアクタンス及びキャパシタンス検知プラットフォーム
EP3523626A1 (en) * 2016-10-07 2019-08-14 Boehringer Ingelheim Vetmedica GmbH Analysis system and method for testing a sample

Also Published As

Publication number Publication date
CN205538786U (zh) 2016-08-31
EP3207362A1 (en) 2017-08-23
EP3207362A4 (en) 2018-05-09
WO2016064635A1 (en) 2016-04-28
CN115963149A (zh) 2023-04-14
EP3207362C0 (en) 2024-05-01
AU2015336363B2 (en) 2021-03-04
JP2017532033A (ja) 2017-11-02
CA2964310A1 (en) 2016-04-28
ES2982089T3 (es) 2024-10-14
US12031118B2 (en) 2024-07-09
US20170240855A1 (en) 2017-08-24
EP3207362B1 (en) 2024-05-01
AU2015336363A1 (en) 2017-05-04
US10808217B2 (en) 2020-10-20
JP6795495B2 (ja) 2020-12-02
US20200407677A1 (en) 2020-12-31
CN107110803A (zh) 2017-08-29

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