CA2964310C - Reactance and capacitance sensing platform for detecting microorganisms - Google Patents

Reactance and capacitance sensing platform for detecting microorganisms Download PDF

Info

Publication number
CA2964310C
CA2964310C CA2964310A CA2964310A CA2964310C CA 2964310 C CA2964310 C CA 2964310C CA 2964310 A CA2964310 A CA 2964310A CA 2964310 A CA2964310 A CA 2964310A CA 2964310 C CA2964310 C CA 2964310C
Authority
CA
Canada
Prior art keywords
sample
impedance
khz
electrodes
vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2964310A
Other languages
English (en)
French (fr)
Other versions
CA2964310A1 (en
Inventor
Patrick Shawn Beaty
Michael A. Brasch
Suneil HOSMANE
David Polley
Julie L. Rosales
Kerry Lynn Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of CA2964310A1 publication Critical patent/CA2964310A1/en
Application granted granted Critical
Publication of CA2964310C publication Critical patent/CA2964310C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48785Electrical and electronic details of measuring devices for physical analysis of liquid biological material not specific to a particular test method, e.g. user interface or power supply
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026Dielectric impedance spectroscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Sustainable Development (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Human Computer Interaction (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2964310A 2014-10-14 2015-10-14 Reactance and capacitance sensing platform for detecting microorganisms Active CA2964310C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462063602P 2014-10-14 2014-10-14
US62/063,602 2014-10-14
PCT/US2015/055501 WO2016064635A1 (en) 2014-10-14 2015-10-14 Reactance and capacitance sensing platform for detecting microorganisms

Publications (2)

Publication Number Publication Date
CA2964310A1 CA2964310A1 (en) 2016-04-28
CA2964310C true CA2964310C (en) 2019-02-26

Family

ID=55761340

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2964310A Active CA2964310C (en) 2014-10-14 2015-10-14 Reactance and capacitance sensing platform for detecting microorganisms

Country Status (8)

Country Link
US (2) US10808217B2 (enExample)
EP (1) EP3207362B1 (enExample)
JP (1) JP6795495B2 (enExample)
CN (3) CN107110803A (enExample)
AU (1) AU2015336363B2 (enExample)
CA (1) CA2964310C (enExample)
ES (1) ES2982089T3 (enExample)
WO (1) WO2016064635A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
US10808217B2 (en) 2014-10-14 2020-10-20 Becton Dickinson And Company Reactance and capacitance sensing platform for detecting microorganisms
CN109996888A (zh) * 2016-09-23 2019-07-09 阿尔韦奥科技公司 用于检测分析物的方法和组合物
WO2019147225A1 (en) * 2018-01-24 2019-08-01 Hewlett-Packard Development Company, L.P. Fluidic property determination from fluid impedances
US20190241861A1 (en) * 2018-02-02 2019-08-08 Karmel Alon Allison Bacterial detection system
WO2020132008A1 (en) 2018-12-20 2020-06-25 Alveo Technologies, Inc. Handheld impedance-based diagnostic test system for detecting analytes
US12472492B2 (en) 2020-08-14 2025-11-18 Alveo Technologies, Inc. Systems and methods of sample depositing and testing
CN113406153B (zh) * 2021-06-29 2022-06-07 毕玉琦 一种食品菌群快速检测装置
US12474250B2 (en) * 2023-06-27 2025-11-18 International Business Machines Corporation Linear fluidic cell trap device for single cell detection

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW418323B (en) * 1998-02-19 2001-01-11 Sumitomo Metal Ind Capacitance detection system and method
WO2000022431A1 (en) * 1998-10-09 2000-04-20 Simon Feldberg Method and apparatus for determining and evaluating bacterial populations
EP1162449A1 (en) * 2000-06-06 2001-12-12 Universiteit Gent AC-based gate detection method and device for the sizing of colloidal particles, cells and bacteria in liquids
US6649402B2 (en) 2001-06-22 2003-11-18 Wisconsin Alumni Research Foundation Microfabricated microbial growth assay method and apparatus
US6433560B1 (en) * 2001-08-31 2002-08-13 Eaton Corporation Combined fluid condition monitor and fluid level sensor
WO2006048456A1 (en) * 2004-11-05 2006-05-11 Graceton Finance Sa Method and device for the detection, measurement and analysis of biological, bioactive, bioenergetic and bioharmonic signals
US8318099B2 (en) 2005-10-26 2012-11-27 General Electric Company Chemical and biological sensors, systems and methods based on radio frequency identification
US7923241B2 (en) * 2007-10-10 2011-04-12 Corning Incorporated Cell culture article and methods thereof
PL2271933T3 (pl) * 2008-05-07 2013-05-31 Univ Strathclyde System i sposób charakteryzowania komórek
CN101698879A (zh) 2009-10-14 2010-04-28 电子科技大学 检测细菌培养基电阻抗曲线形态的药物敏感试验方法
TW201226896A (en) * 2010-12-17 2012-07-01 Univ Yuanpei Microbe or cell inspection system and method thereof
CN102954985A (zh) * 2011-08-31 2013-03-06 中国科学院上海微系统与信息技术研究所 一种电阻抗式细菌快速检测传感器的数据分析方法
WO2013123189A1 (en) * 2012-02-15 2013-08-22 Becton, Dickinson And Company Impedence-based bacterial detection system
US10808217B2 (en) 2014-10-14 2020-10-20 Becton Dickinson And Company Reactance and capacitance sensing platform for detecting microorganisms
EP3523626A1 (en) * 2016-10-07 2019-08-14 Boehringer Ingelheim Vetmedica GmbH Analysis system and method for testing a sample

Also Published As

Publication number Publication date
AU2015336363B2 (en) 2021-03-04
CA2964310A1 (en) 2016-04-28
EP3207362A4 (en) 2018-05-09
WO2016064635A1 (en) 2016-04-28
EP3207362A1 (en) 2017-08-23
US10808217B2 (en) 2020-10-20
CN115963149A (zh) 2023-04-14
JP6795495B2 (ja) 2020-12-02
ES2982089T3 (es) 2024-10-14
JP2017532033A (ja) 2017-11-02
EP3207362B1 (en) 2024-05-01
US20200407677A1 (en) 2020-12-31
CN205538786U (zh) 2016-08-31
CN107110803A (zh) 2017-08-29
US12031118B2 (en) 2024-07-09
AU2015336363A1 (en) 2017-05-04
US20170240855A1 (en) 2017-08-24
EP3207362C0 (en) 2024-05-01

Similar Documents

Publication Publication Date Title
US12031118B2 (en) Reactance and capacitance sensing platform for detecting microorganisms
US9709516B2 (en) Impedance-based bacterial detection system
US9400272B2 (en) Detection method and apparatus for detecting microbial growth
Grossi et al. Measurement of bacterial concentration using a portable sensor system with a combined electrical-optical approach
Vlasov et al. Electronic tongue: Chemical sensor systems for analysis of aquatic media
RU2319140C2 (ru) Детектор магнитной проницаемости с компенсацией дрейфа
de Faria et al. Recent trends in the electroanalytical detection of food fraud
JP2005304376A (ja) 生体検出方法および生体検出装置
US20230408432A1 (en) Non-contact impedance analyzer for real-time detection of microbial growth
Al Ahmad et al. Monitoring of Yeast Cell Volume Changes Using Electrical Impedance Spectroscopy
WO2000022431A1 (en) Method and apparatus for determining and evaluating bacterial populations
Goh et al. Impedance spectroscopy for in situ biomass measurements in microbioreactor
Bhatt et al. A historical perspective on impedance spectroscopy and its application in biological detection
Cantons Villar Online bioimpedance measurement: characterisation and application in bosystems engineering
Salwa et al. Ultrasonic transducer kit for bacteria growth monitoring system
Manuel Gutierrez et al. Bio-Inspired Systems Patents: Electronic Tongues
Mazzoneb et al. CHEMICAL IMAGES OF LIQUIDS

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170410