CA2960902C - Biosensors for monitoring biomolecule localization and trafficking in cells - Google Patents
Biosensors for monitoring biomolecule localization and trafficking in cells Download PDFInfo
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- CA2960902C CA2960902C CA2960902A CA2960902A CA2960902C CA 2960902 C CA2960902 C CA 2960902C CA 2960902 A CA2960902 A CA 2960902A CA 2960902 A CA2960902 A CA 2960902A CA 2960902 C CA2960902 C CA 2960902C
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
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| US201462052738P | 2014-09-19 | 2014-09-19 | |
| US62/052,738 | 2014-09-19 | ||
| PCT/CA2015/050924 WO2016041093A1 (en) | 2014-09-19 | 2015-09-21 | Biosensors for monitoring biomolecule localization and trafficking in cells |
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| CA2960902A1 CA2960902A1 (en) | 2016-03-24 |
| CA2960902C true CA2960902C (en) | 2023-10-24 |
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| WO (1) | WO2016041093A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
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| JP2020537531A (ja) * | 2017-10-18 | 2020-12-24 | ユニベルシテ ドゥ モントリオール | Ｇタンパク質活性化の評価のためのシステムおよび方法 |
| WO2020037213A1 (en) | 2018-08-17 | 2020-02-20 | Genentech, Inc. | In vitro transcytosis assay |
| WO2020101878A2 (en) * | 2018-10-29 | 2020-05-22 | The Johns Hopkins University | Rasopathy treatment |
| US20220106382A1 (en) * | 2019-01-22 | 2022-04-07 | Paul Scherrer Institut | Beta-arrestin mutants |
| MX2022001516A (es) | 2019-08-06 | 2022-03-11 | Domain Therapeutics | Antagonistas del receptor de neuropeptido ff. |
| CN110981943B (zh) * | 2019-12-02 | 2021-08-03 | 清华大学 | 多肽及其在制备药物中的用途和药物 |
| WO2022108741A1 (en) * | 2020-11-19 | 2022-05-27 | University Of Houston System | Monitoring membrane protein trafficking for drug discovery and drug development |
| CN114200128B (zh) * | 2021-11-24 | 2024-09-27 | 中国科学院生物物理研究所 | 二维蛋白纳米阵列作为免疫传感元件载体的制备和应用 |
| CN114767832B (zh) * | 2022-04-21 | 2025-05-16 | 深圳辰扬生物科技有限公司 | 多肽及其用途 |
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| US7109315B2 (en) * | 2000-03-15 | 2006-09-19 | Bruce J. Bryan | Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
| WO2003033650A2 (en) * | 2001-10-15 | 2003-04-24 | Stratagene | Recombinant renilla reniformis system for bioluminescence resonance energy transfer |
| CA2607015C (en) | 2004-05-04 | 2016-07-05 | Universite De Montreal | Double brilliance beta-arrestin: a biosensor for monitoring the activity of receptors and signalling molecules, and method of using same |
| KR101834574B1 (ko) | 2009-01-29 | 2018-03-05 | 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 | Ｇ 단백질 커플링 수용체 활성화 측정 |
| WO2011067202A1 (en) | 2009-12-02 | 2011-06-09 | Unilever Nv | Improved method for screening a potential modulator compound of a taste receptor |
| WO2011130540A1 (en) | 2010-04-14 | 2011-10-20 | Duke University | Light stimulated protein interaction molecules and methods of use |
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2015
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- 2015-09-21 DK DK15841561.2T patent/DK3194960T3/da active
- 2015-09-21 CN CN201580062566.XA patent/CN107533049B/zh active Active
- 2015-09-21 JP JP2017515812A patent/JP6708633B2/ja active Active
- 2015-09-21 WO PCT/CA2015/050924 patent/WO2016041093A1/en not_active Ceased
- 2015-09-21 EP EP15841561.2A patent/EP3194960B1/en active Active
- 2015-09-21 SG SG11201702133TA patent/SG11201702133TA/en unknown
- 2015-09-21 NZ NZ730131A patent/NZ730131A/en unknown
- 2015-09-21 US US15/512,267 patent/US10584159B2/en active Active
- 2015-09-21 PL PL15841561T patent/PL3194960T3/pl unknown
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- 2015-09-21 ES ES15841561T patent/ES2774416T3/es active Active
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2017
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2020
- 2020-01-30 US US16/777,504 patent/US20200157184A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL3194960T3 (pl) | 2020-06-01 |
| JP6708633B2 (ja) | 2020-06-10 |
| CA2960902A1 (en) | 2016-03-24 |
| US10584159B2 (en) | 2020-03-10 |
| DK3194960T3 (da) | 2020-02-17 |
| JP2017534851A (ja) | 2017-11-24 |
| SG11201702133TA (en) | 2017-04-27 |
| US20170313762A1 (en) | 2017-11-02 |
| NZ730131A (en) | 2023-05-26 |
| AU2015318567A1 (en) | 2017-04-06 |
| WO2016041093A1 (en) | 2016-03-24 |
| CN107533049A (zh) | 2018-01-02 |
| EP3194960B1 (en) | 2019-12-04 |
| US20200157184A1 (en) | 2020-05-21 |
| ES2774416T3 (es) | 2020-07-21 |
| EP3194960A1 (en) | 2017-07-26 |
| CN107533049B (zh) | 2020-11-20 |
| EP3194960A4 (en) | 2018-03-07 |
| AU2015318567B2 (en) | 2020-11-05 |
| IL251158A0 (en) | 2017-04-30 |
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