CA2959110A1 - Use of elsiglutide to treat gastrointestinal mucositis including chemotherapy-induced diarrhea - Google Patents

Use of elsiglutide to treat gastrointestinal mucositis including chemotherapy-induced diarrhea Download PDF

Info

Publication number
CA2959110A1
CA2959110A1 CA2959110A CA2959110A CA2959110A1 CA 2959110 A1 CA2959110 A1 CA 2959110A1 CA 2959110 A CA2959110 A CA 2959110A CA 2959110 A CA2959110 A CA 2959110A CA 2959110 A1 CA2959110 A1 CA 2959110A1
Authority
CA
Canada
Prior art keywords
elsiglutide
chemotherapy
cancer
cycle
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2959110A
Other languages
English (en)
French (fr)
Inventor
Ruben Giorgino
Simona Roncoroni
Selma Calcagnile
Fabio Trento
Riccardo Spezia
Cecilia Moresino
Carsten Boye Knudsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helsinn Healthcare SA
Zealand Pharma AS
Original Assignee
Helsinn Healthcare SA
Zealand Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinn Healthcare SA, Zealand Pharma AS filed Critical Helsinn Healthcare SA
Publication of CA2959110A1 publication Critical patent/CA2959110A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2959110A 2014-09-10 2015-09-02 Use of elsiglutide to treat gastrointestinal mucositis including chemotherapy-induced diarrhea Abandoned CA2959110A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462048520P 2014-09-10 2014-09-10
US62/048,520 2014-09-10
PCT/IB2015/001922 WO2016038455A1 (en) 2014-09-10 2015-09-02 Use of elsiglutide to treat gastrointestinal mucositis including chemotherapy-induced diarrhea

Publications (1)

Publication Number Publication Date
CA2959110A1 true CA2959110A1 (en) 2016-03-17

Family

ID=54548212

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2959110A Abandoned CA2959110A1 (en) 2014-09-10 2015-09-02 Use of elsiglutide to treat gastrointestinal mucositis including chemotherapy-induced diarrhea

Country Status (18)

Country Link
US (1) US20160067311A1 (enExample)
EP (1) EP3191115A1 (enExample)
JP (1) JP2017532308A (enExample)
KR (1) KR20170052661A (enExample)
CN (1) CN107073081A (enExample)
AR (1) AR103119A1 (enExample)
AU (1) AU2015313919A1 (enExample)
BR (1) BR112017004577A2 (enExample)
CA (1) CA2959110A1 (enExample)
CL (1) CL2017000563A1 (enExample)
EA (1) EA201790552A1 (enExample)
IL (1) IL250928A0 (enExample)
MA (1) MA40623A (enExample)
MX (1) MX2017003166A (enExample)
PH (1) PH12017500426A1 (enExample)
SG (1) SG11201701690WA (enExample)
TW (1) TW201613634A (enExample)
WO (1) WO2016038455A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170087216A1 (en) * 2015-09-17 2017-03-30 Helsinn Healthcare Sa Therapeutic Uses of Elsiglutide
US11389424B2 (en) 2017-03-09 2022-07-19 Napo Pharmaceuticals, Inc. Methods and compositions for treating chemotherapy-induced diarrhea
EP4424362A3 (en) * 2017-06-16 2024-11-27 Zealand Pharma A/S Dosage regimes for the administration of glucagon-like-peptide-2 (glp-2) analogues
BR112022025741A2 (pt) * 2020-06-19 2023-01-03 Napo Pharmaceuticals Inc Usos de composições compreendendo crofelemer para tratamento de diarreia induzida por quimioterapia (cid)
CN115054683B (zh) * 2022-05-19 2023-06-09 唐颢 胰高血糖素样肽-2在制备缓解阿霉素心脏毒性药物中的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200709027B (en) * 2005-04-22 2009-01-28 Novacea Inc Treatment, prevention and amelioration of pulmonary disorders associated with chemotherapy or radiotherapy with active vitamin D compounds or mimics thereof
CN101171262B (zh) * 2005-05-04 2012-06-27 西兰制药公司 胰高血糖素样肽-2(glp-2)类似物
EP2314616A1 (en) * 2009-10-23 2011-04-27 Ferring B.V. Peptidic GLP-2 agonists

Also Published As

Publication number Publication date
WO2016038455A1 (en) 2016-03-17
TW201613634A (en) 2016-04-16
CL2017000563A1 (es) 2017-09-29
MA40623A (fr) 2016-03-17
EA201790552A1 (ru) 2017-08-31
US20160067311A1 (en) 2016-03-10
PH12017500426A1 (en) 2017-07-31
EP3191115A1 (en) 2017-07-19
BR112017004577A2 (pt) 2018-01-23
SG11201701690WA (en) 2017-04-27
IL250928A0 (en) 2017-04-30
JP2017532308A (ja) 2017-11-02
KR20170052661A (ko) 2017-05-12
CN107073081A (zh) 2017-08-18
AU2015313919A1 (en) 2017-03-16
MX2017003166A (es) 2017-06-19
AR103119A1 (es) 2017-04-19

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200903