CA2956778C - Water buffalo derived peptide antibiotic therapies - Google Patents

Water buffalo derived peptide antibiotic therapies Download PDF

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Publication number
CA2956778C
CA2956778C CA2956778A CA2956778A CA2956778C CA 2956778 C CA2956778 C CA 2956778C CA 2956778 A CA2956778 A CA 2956778A CA 2956778 A CA2956778 A CA 2956778A CA 2956778 C CA2956778 C CA 2956778C
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Canada
Prior art keywords
group
trp
leu
ile
antimicrobial
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Active
Application number
CA2956778A
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English (en)
French (fr)
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CA2956778A1 (en
Inventor
Luis Tonatiuh Melgarejo GARCIA
Annika LINDE
Gerald Henry LUSHINGTON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centaur Inc
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Centaur Inc
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Publication of CA2956778A1 publication Critical patent/CA2956778A1/en
Application granted granted Critical
Publication of CA2956778C publication Critical patent/CA2956778C/en
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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2956778A 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies Active CA2956778C (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462032737P 2014-08-04 2014-08-04
US62/032,737 2014-08-04
US14/483,083 US9029319B1 (en) 2014-08-04 2014-09-10 Water buffalo derived peptide antibiotic therapies
US14/483,083 2014-09-10
US14/678,558 US9273097B2 (en) 2014-08-04 2015-04-03 Water buffalo derived peptide antibiotic therapies
US14/678,558 2015-04-03
US14/692,518 US9163064B1 (en) 2014-08-04 2015-04-21 Water buffalo derived monomeric peptides containing proline for antibiotic therapies
US14/692,518 2015-04-21
US14/750,709 US9701716B2 (en) 2014-08-04 2015-06-25 Water buffalo derived dimeric peptide containing proline for antibiotic therapies
US14/750,709 2015-06-25
PCT/US2015/042435 WO2016022335A1 (en) 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies

Publications (2)

Publication Number Publication Date
CA2956778A1 CA2956778A1 (en) 2016-02-11
CA2956778C true CA2956778C (en) 2021-10-26

Family

ID=53038201

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2956778A Active CA2956778C (en) 2014-08-04 2015-07-28 Water buffalo derived peptide antibiotic therapies

Country Status (21)

Country Link
US (4) US9029319B1 (https=)
EP (1) EP3179855B1 (https=)
JP (1) JP6802148B2 (https=)
CN (1) CN108064131A (https=)
AR (1) AR101416A1 (https=)
AU (1) AU2015298629B2 (https=)
BR (1) BR112017002166B1 (https=)
CA (1) CA2956778C (https=)
CY (1) CY1122747T1 (https=)
DK (1) DK3179855T3 (https=)
ES (1) ES2770705T3 (https=)
HR (1) HRP20200195T1 (https=)
HU (1) HUE048461T2 (https=)
LT (1) LT3179855T (https=)
MX (1) MX373912B (https=)
PL (1) PL3179855T3 (https=)
PT (1) PT3179855T (https=)
RS (1) RS59987B1 (https=)
SI (1) SI3179855T1 (https=)
SM (1) SMT202000100T1 (https=)
WO (1) WO2016022335A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9029319B1 (en) * 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies
CN109553677B (zh) * 2018-11-30 2021-12-14 东北农业大学 基于两栖类蛙源抗菌肽的衍生肽w8及其制备方法和应用
EP4129064A4 (en) * 2020-03-30 2023-12-13 Anygen Co., Ltd. NEW ANTIBACTERIAL PEPTIDE AND USE THEREOF
CN113831395B (zh) 2021-11-26 2022-02-22 中国海洋大学 一种重组抗菌肽TrSub、制备方法及其应用
CN119220434B (zh) * 2024-09-25 2025-05-30 青岛农业大学 一种具有高载硒活性的丁酸梭菌的菌制剂后生元及其应用
CN120842027B (zh) * 2025-08-12 2026-04-24 山东植知源生态工程有限公司 一种含大豆磷脂和羽毛粉的生物有机肥及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053342A1 (en) * 2000-01-21 2001-07-26 The Burnham Institute Chimeric prostate-homing peptides with pro-apoptotic activity
US8202835B2 (en) 2005-06-17 2012-06-19 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
DE102009007381A1 (de) * 2009-01-29 2010-08-05 Amp-Therapeutics Gmbh & Co. Kg Antibiotische Peptide
JP5701777B2 (ja) * 2009-02-06 2015-04-15 テクノファージ， インベスティガサン エ デセンボルビメント エム ビオテクノロジア，エスエー 抗菌性ファージ、ファージペプチド、及びそれらの使用方法
US9029319B1 (en) 2014-08-04 2015-05-12 Centaur, Inc. Water buffalo derived peptide antibiotic therapies

Also Published As

Publication number Publication date
PT3179855T (pt) 2020-02-21
EP3179855A4 (en) 2018-05-23
JP2017533177A (ja) 2017-11-09
US9273097B2 (en) 2016-03-01
MX373912B (es) 2020-07-10
EP3179855B1 (en) 2019-11-20
AU2015298629A1 (en) 2017-02-16
AR101416A1 (es) 2016-12-14
RS59987B1 (sr) 2020-03-31
WO2016022335A1 (en) 2016-02-11
HUE048461T2 (hu) 2020-07-28
JP6802148B2 (ja) 2020-12-16
US20160031940A1 (en) 2016-02-04
US20160031954A1 (en) 2016-02-04
CY1122747T1 (el) 2021-03-12
SI3179855T1 (sl) 2020-04-30
AU2015298629B2 (en) 2019-03-07
BR112017002166B1 (pt) 2022-08-16
MX2017001566A (es) 2017-10-12
NZ728651A (en) 2021-11-26
US9701716B2 (en) 2017-07-11
US9163064B1 (en) 2015-10-20
DK3179855T3 (da) 2020-02-17
EP3179855A1 (en) 2017-06-21
PL3179855T3 (pl) 2020-06-29
BR112017002166A2 (pt) 2018-01-16
HRP20200195T1 (hr) 2020-08-07
CA2956778A1 (en) 2016-02-11
SMT202000100T1 (it) 2020-03-13
ES2770705T3 (es) 2020-07-02
LT3179855T (lt) 2020-02-25
US9029319B1 (en) 2015-05-12
CN108064131A (zh) 2018-05-22

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