CA2947252C - Administration of citicoline to improve cognitive performance, attentional performance, and motor function - Google Patents

Administration of citicoline to improve cognitive performance, attentional performance, and motor function Download PDF

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Publication number
CA2947252C
CA2947252C CA2947252A CA2947252A CA2947252C CA 2947252 C CA2947252 C CA 2947252C CA 2947252 A CA2947252 A CA 2947252A CA 2947252 A CA2947252 A CA 2947252A CA 2947252 C CA2947252 C CA 2947252C
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CA2947252A
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English (en)
French (fr)
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CA2947252A1 (en
Inventor
Deborah Yurgelun-Todd
Perry Renshaw
Miho Takada
Takeshi Ikeda
Masahiko Morita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Hakko Bio Co Ltd
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Kyowa Hakko Bio Co Ltd
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Application filed by Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Bio Co Ltd
Publication of CA2947252A1 publication Critical patent/CA2947252A1/en
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Publication of CA2947252C publication Critical patent/CA2947252C/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA2947252A 2014-04-30 2015-04-30 Administration of citicoline to improve cognitive performance, attentional performance, and motor function Active CA2947252C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461986502P 2014-04-30 2014-04-30
US61/986,502 2014-04-30
PCT/IB2015/053178 WO2015166463A1 (en) 2014-04-30 2015-04-30 Administration of citicoline to improve cognitive performance, attentional performance, and motor function

Publications (2)

Publication Number Publication Date
CA2947252A1 CA2947252A1 (en) 2015-11-05
CA2947252C true CA2947252C (en) 2022-05-10

Family

ID=54358252

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2947252A Active CA2947252C (en) 2014-04-30 2015-04-30 Administration of citicoline to improve cognitive performance, attentional performance, and motor function

Country Status (8)

Country Link
US (2) US11583546B2 (enExample)
EP (1) EP3137067B1 (enExample)
JP (1) JP6584430B2 (enExample)
AU (1) AU2015254865B2 (enExample)
CA (1) CA2947252C (enExample)
ES (1) ES2915909T3 (enExample)
PL (1) PL3137067T3 (enExample)
WO (1) WO2015166463A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance
JP6584430B2 (ja) 2014-04-30 2019-10-02 協和発酵バイオ株式会社 認知パフォーマンス、注意パフォーマンス、及び運動機能を改善するためのシチコリン投与

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020198172A1 (en) * 1997-12-01 2002-12-26 Sandage Bobby W. Method of treating motor neuron diseases and demyelinating diseases with citicoline
US20070004670A1 (en) * 1998-07-31 2007-01-04 Richard Wurtman Compositions containing citicoline, and methods of use thereof
US20030114415A1 (en) * 2001-12-14 2003-06-19 Wurtman Richard J. Compositions and methods for treating and preventing memory impairment using citicoline
CA2517290A1 (en) * 2003-02-26 2004-09-10 Kyowa Hakko Kogyo Co., Ltd. Muscle-building agent and preventive or remedy for muscle weakening
US20070248696A1 (en) * 2006-04-25 2007-10-25 Mind Sports Nutrition Inc. Composition and method for enhancing neuromuscular facilitation and cognitive functions
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance
US20100041620A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods for improving frontal brain bioenergetic metabolism
NZ707081A (en) * 2012-10-30 2019-03-29 Kyowa Hakko Bio Co Ltd Agent for preventing or improving decline in brain function
US9883831B1 (en) * 2014-01-30 2018-02-06 Texas Health Biomedical Advancement Center, Inc. Digital medical evaluation and testing on a touch screen device
JP6584430B2 (ja) 2014-04-30 2019-10-02 協和発酵バイオ株式会社 認知パフォーマンス、注意パフォーマンス、及び運動機能を改善するためのシチコリン投与

Also Published As

Publication number Publication date
US20170049796A1 (en) 2017-02-23
JP6584430B2 (ja) 2019-10-02
AU2015254865B2 (en) 2020-07-02
US20230181614A1 (en) 2023-06-15
US12115181B2 (en) 2024-10-15
JP2017520513A (ja) 2017-07-27
EP3137067A1 (en) 2017-03-08
CA2947252A1 (en) 2015-11-05
NZ725643A (en) 2021-08-27
ES2915909T3 (es) 2022-06-27
PL3137067T3 (pl) 2022-06-27
WO2015166463A1 (en) 2015-11-05
EP3137067A4 (en) 2017-12-27
AU2015254865A1 (en) 2016-11-24
EP3137067B1 (en) 2022-05-04
US11583546B2 (en) 2023-02-21

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