CA2945414C - Method of isolating a target cell - Google Patents
Method of isolating a target cell Download PDFInfo
- Publication number
- CA2945414C CA2945414C CA2945414A CA2945414A CA2945414C CA 2945414 C CA2945414 C CA 2945414C CA 2945414 A CA2945414 A CA 2945414A CA 2945414 A CA2945414 A CA 2945414A CA 2945414 C CA2945414 C CA 2945414C
- Authority
- CA
- Canada
- Prior art keywords
- binding
- reagent
- ligand
- streptavidin
- receptor molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
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| PCT/EP2015/059510 WO2015166049A1 (en) | 2014-04-30 | 2015-04-30 | Method of isolating a target cell |
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| CA2945414A1 CA2945414A1 (en) | 2015-11-05 |
| CA2945414C true CA2945414C (en) | 2023-05-09 |
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| US10228312B2 (en) | 2012-02-23 | 2019-03-12 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| PT3132247T (pt) * | 2014-04-16 | 2021-11-03 | Juno Therapeutics Gmbh | Métodos, kits e aparelho para ampliar uma população de células |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| WO2017068419A2 (en) | 2015-10-22 | 2017-04-27 | Juno Therapeutics Gmbh | Methods, kits, agents and apparatuses for transduction |
| MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
| WO2018197949A1 (en) | 2017-04-27 | 2018-11-01 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| KR102088277B1 (ko) * | 2018-04-27 | 2020-03-13 | 주식회사 유니언스진 | 면역 화학 진단법을 이용한 표적 항원 검출용 종이기반 3차원 구조의 미세칩과 이를 이용한 표적항원 검출 방법 |
| CN112912103B (zh) * | 2018-05-21 | 2025-08-29 | 广州邦定生物技术有限公司 | 多价蛋白质复合物 |
| US11604191B2 (en) * | 2018-08-31 | 2023-03-14 | Thermogenesis Corporation | Methods for isolating target cells from blood |
| JP7502451B2 (ja) * | 2020-01-31 | 2024-06-18 | セル．コペディア ゲーエムベーハー | 生物学的実体を単離する方法 |
| WO2023017115A1 (en) * | 2021-08-11 | 2023-02-16 | Iba Lifesciences Gmbh | Fractionation of cells based on a marker protein |
| AU2023259664A1 (en) | 2022-04-28 | 2024-11-07 | Bio-Recell Ltd. | Method for separating target cells |
| WO2025238197A1 (en) * | 2024-05-16 | 2025-11-20 | Iba Lifesciences Gmbh | Functionalized three-dimensional (3d) polymer scaffold for affinity chromatography |
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| JP2624470B2 (ja) | 1984-10-02 | 1997-06-25 | バイオジェン インコーポレイテッド | ストレプトアビジン様ポリペプチドの製造 |
| US4851341A (en) | 1986-12-19 | 1989-07-25 | Immunex Corporation | Immunoaffinity purification system |
| DE4237113B4 (de) | 1992-11-03 | 2006-10-12 | "Iba Gmbh" | Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins |
| AU5132096A (en) | 1995-01-30 | 1996-08-21 | Terrapin Technologies, Inc. | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
| AU708375B2 (en) | 1995-02-09 | 1999-08-05 | University Of Washington | Modified-affinity streptavidin |
| US6022951A (en) | 1995-04-11 | 2000-02-08 | Univ Boston | Streptavidin mutants |
| DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| CA2283716A1 (en) | 1997-03-14 | 1998-09-17 | Gabriel O. Reznik | Multiflavor streptavidin |
| US5985658A (en) | 1997-11-14 | 1999-11-16 | Health Research Incorporated | Calmodulin-based cell separation technique |
| DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
| EP1227321A1 (en) | 2000-12-28 | 2002-07-31 | Institut für Bioanalytik GmbH | Reversible MHC multimer staining for functional purification of antigen-specific T cells |
| DE10113776B4 (de) | 2001-03-21 | 2012-08-09 | "Iba Gmbh" | Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| JP4776619B2 (ja) | 2005-04-19 | 2011-09-21 | パナソニック株式会社 | 位置センサ、光ヘッド装置、ヘッド移動機構、情報記録再生装置、および位置制御システム |
| WO2008140573A2 (en) * | 2006-11-15 | 2008-11-20 | Invitrogen Dynal As | Methods for reversibly binding a biotin compound to a support |
| US8008032B2 (en) * | 2008-02-25 | 2011-08-30 | Cellective Dx Corporation | Tagged ligands for enrichment of rare analytes from a mixed sample |
| US10023657B2 (en) * | 2010-10-01 | 2018-07-17 | Ludwig Institute For Cancer Research Ltd. | Reversible protein multimers, methods for their production and use |
| SI2734538T2 (sl) * | 2011-07-18 | 2024-10-30 | Iba Lifesciences Gmbh | Postopek za reverzibilno obarvanje tarčne celice |
| US10228312B2 (en) * | 2012-02-23 | 2019-03-12 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
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2015
- 2015-04-30 AU AU2015254588A patent/AU2015254588B2/en active Active
- 2015-04-30 WO PCT/EP2015/059510 patent/WO2015166049A1/en not_active Ceased
- 2015-04-30 US US15/306,995 patent/US11150239B2/en active Active
- 2015-04-30 EP EP15723655.5A patent/EP3137905B1/en active Active
- 2015-04-30 CN CN201580035819.4A patent/CN106662584B/zh active Active
- 2015-04-30 CA CA2945414A patent/CA2945414C/en active Active
- 2015-04-30 JP JP2016565162A patent/JP6678593B2/ja active Active
Also Published As
| Publication number | Publication date |
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| EP3137905B1 (en) | 2021-01-13 |
| US11150239B2 (en) | 2021-10-19 |
| JP6678593B2 (ja) | 2020-04-08 |
| WO2015166049A1 (en) | 2015-11-05 |
| CN106662584B (zh) | 2020-05-05 |
| AU2015254588A1 (en) | 2016-11-10 |
| EP3137905A1 (en) | 2017-03-08 |
| AU2015254588B2 (en) | 2020-05-21 |
| US20170052176A1 (en) | 2017-02-23 |
| JP2017514481A (ja) | 2017-06-08 |
| CN106662584A (zh) | 2017-05-10 |
| CA2945414A1 (en) | 2015-11-05 |
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| CA3163761C (en) | Methods of isolating a biological entity | |
| HK1202335B (en) | Chromatographic isolation of cells and other complex biological materials |
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