CA2943797A1 - Modulation of calcium ion homeostasis in harvested transplantable hearts - Google Patents

Modulation of calcium ion homeostasis in harvested transplantable hearts Download PDF

Info

Publication number
CA2943797A1
CA2943797A1 CA2943797A CA2943797A CA2943797A1 CA 2943797 A1 CA2943797 A1 CA 2943797A1 CA 2943797 A CA2943797 A CA 2943797A CA 2943797 A CA2943797 A CA 2943797A CA 2943797 A1 CA2943797 A1 CA 2943797A1
Authority
CA
Canada
Prior art keywords
mmol
heart
reperfusion
hearts
harvested
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2943797A
Other languages
English (en)
French (fr)
Inventor
Christopher White
Darren FREED
Larry Hryshko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2943797A1 publication Critical patent/CA2943797A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
CA2943797A 2014-04-10 2015-04-10 Modulation of calcium ion homeostasis in harvested transplantable hearts Abandoned CA2943797A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461978132P 2014-04-10 2014-04-10
US61/978,132 2014-04-10
PCT/CA2015/050297 WO2015154193A1 (en) 2014-04-10 2015-04-10 Modulation of calcium ion homeostasis in harvested transplantable hearts

Publications (1)

Publication Number Publication Date
CA2943797A1 true CA2943797A1 (en) 2015-10-15

Family

ID=54287064

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2943797A Abandoned CA2943797A1 (en) 2014-04-10 2015-04-10 Modulation of calcium ion homeostasis in harvested transplantable hearts

Country Status (8)

Country Link
US (1) US10327441B2 (cg-RX-API-DMAC7.html)
EP (1) EP3128836B1 (cg-RX-API-DMAC7.html)
CN (1) CN107734967B (cg-RX-API-DMAC7.html)
AU (1) AU2015245903A1 (cg-RX-API-DMAC7.html)
BR (1) BR112016023394B1 (cg-RX-API-DMAC7.html)
CA (1) CA2943797A1 (cg-RX-API-DMAC7.html)
ES (1) ES2834388T3 (cg-RX-API-DMAC7.html)
WO (1) WO2015154193A1 (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ600702A (en) 2004-10-07 2013-12-20 Transmedics Inc Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US8420380B2 (en) 2008-01-31 2013-04-16 Transmedics, Inc. Systems and methods for ex vivo lung care
DK4032401T3 (da) 2011-04-14 2025-12-15 Transmedics Inc Fremgangsmåde til fremstilling af en organplejeopløsning til maskinperfusion ex-vivo af donorlunger
US10433539B2 (en) * 2014-04-10 2019-10-08 Tevosol, Inc. Composition and solution with controlled calcium ion level, and related method and use for reperfusion
CN106659151B (zh) 2014-06-02 2021-06-08 特兰斯迈迪茨公司 离体器官护理系统
BR112017008076B1 (pt) * 2014-10-24 2021-06-29 Darren Freed Solução com nível de íon cálcio controlado, composição para preparação da solução e processo e uso relacionados para reperfusão
CA2970117A1 (en) 2014-12-12 2016-06-16 Darren FREED Apparatus and method for organ perfusion
CN107949419B (zh) 2015-09-09 2021-03-05 特兰斯迈迪茨公司 离体器官护理系统用的主动脉插管
CN114946834B (zh) 2016-05-30 2024-10-25 体沃索股份有限公司 利用变化的外部压力用于离体肺通气的装置和方法
CN109846464A (zh) * 2018-12-29 2019-06-07 曹乃钊 血液流动力学参数的无创测量系统和数据处理系统
CN113975377B (zh) * 2020-07-27 2023-11-10 成都青山利康药业股份有限公司 一种心脏停搏液
CN115400206B (zh) * 2021-05-26 2025-08-15 成都青山利康药业有限公司 一种细胞外液型含血心脏停搏液

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407793A (en) 1991-10-18 1995-04-18 University Of Pittsburgh Of The Commonwealth System Of Higher Education An aqueous heart preservation and cardioplegia solution
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
FR2785501B1 (fr) * 1998-11-10 2001-01-05 Centre Nat Rech Scient Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
EP1207753A4 (en) 1999-06-17 2005-11-30 Univ California CONTINUOUS CARDIAL PERFUSION CONSERVATION WITH PEG-HB FOR IMPROVED HYPOTHERMAL STORAGE
US20030124503A1 (en) 2001-12-28 2003-07-03 Olivencia-Yurvati Albert H. Pyruvate cardioplegia solutions for administration to the heart during cardiopulmonary surgery and methods of use thereof
AUPS312602A0 (en) 2002-06-21 2002-07-18 James Cook University Organ arrest, protection, preservation and recovery
CA2551169A1 (en) 2002-12-23 2004-07-08 Global Cardiac Solutions Pty Ltd Organ preconditioning, arrest, protection, preservation and recovery
GB0903299D0 (en) * 2009-02-26 2009-04-08 Guys And St Thomas Nhs Foundat Composition and methods

Also Published As

Publication number Publication date
WO2015154193A1 (en) 2015-10-15
CN107734967B (zh) 2021-07-16
CN107734967A (zh) 2018-02-23
BR112016023394A2 (cg-RX-API-DMAC7.html) 2017-08-15
AU2015245903A1 (en) 2016-11-17
EP3128836B1 (en) 2020-09-09
ES2834388T3 (es) 2021-06-17
EP3128836A4 (en) 2017-11-22
EP3128836A1 (en) 2017-02-15
BR112016023394B1 (pt) 2021-09-21
US10327441B2 (en) 2019-06-25
US20170020127A1 (en) 2017-01-26

Similar Documents

Publication Publication Date Title
US10327441B2 (en) Modulation of calcium ion homeostasis in harvested transplantable hearts
US11033021B2 (en) Composition and solution with controlled calcium ion level, and related method and use for reperfusion
US12550887B2 (en) Perfusion solution
EP4023066B1 (en) Apparatus for maintenance of harvested hearts for transplanting
CA2965400C (en) Novel composition and solution with controlled calcium ion level, and related method and use for reperfusion
US12082575B2 (en) Perfusion solution
US20100311035A1 (en) Preservation solution for organs and biological tissues

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200831