CA2926342A1 - Compositions pharmaceutiques a base d'estradiol pour insertion vaginale et methodes associees - Google Patents
Compositions pharmaceutiques a base d'estradiol pour insertion vaginale et methodes associees Download PDFInfo
- Publication number
- CA2926342A1 CA2926342A1 CA2926342A CA2926342A CA2926342A1 CA 2926342 A1 CA2926342 A1 CA 2926342A1 CA 2926342 A CA2926342 A CA 2926342A CA 2926342 A CA2926342 A CA 2926342A CA 2926342 A1 CA2926342 A1 CA 2926342A1
- Authority
- CA
- Canada
- Prior art keywords
- pessary
- estradiol
- geometric mean
- patient
- vaginal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
Landscapes
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- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Botany (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Dans divers modes de réalisation, l'invention concerne des compositions pharmaceutiques contenant de l'estradiol solubilisé. Dans divers modes de réalisation, ces compositions sont encapsulées dans des capsules souples qui peuvent être insérées dans le vagin pour le traitement de l'atrophie vulvo-vaginale.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361889483P | 2013-10-10 | 2013-10-10 | |
| US201361894411P | 2013-10-22 | 2013-10-22 | |
| US61/894,411 | 2013-10-22 | ||
| US14/099,562 | 2013-12-05 | ||
| US201461932140P | 2014-01-27 | 2014-01-27 | |
| US61/932,140 | 2014-01-27 | ||
| PCT/US2014/061811 WO2015073177A1 (fr) | 2013-10-10 | 2014-10-22 | Compositions pharmaceutiques à base d'estradiol pour insertion vaginale et méthodes associées |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2926342A1 true CA2926342A1 (fr) | 2015-05-21 |
Family
ID=53140634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2926342A Pending CA2926342A1 (fr) | 2013-10-10 | 2014-10-22 | Compositions pharmaceutiques a base d'estradiol pour insertion vaginale et methodes associees |
Country Status (3)
| Country | Link |
|---|---|
| CA (1) | CA2926342A1 (fr) |
| MX (1) | MX2016005092A (fr) |
| WO (1) | WO2015073177A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2856520C (fr) | 2011-11-23 | 2021-04-06 | Therapeuticsmd, Inc. | Preparations et therapies de substitution pour hormonotherapie naturelle combinee |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| AU2020397648B2 (en) | 2019-12-06 | 2022-03-24 | Prathima Chowdary | Sustained release estrogen vaginal ring pessary for treatment of atrophy, cystitis and uterovaginal prolapse |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1030629A4 (fr) * | 1997-11-03 | 2001-09-05 | Deschutes Medical Products Inc | Pessaire avec cartouche medicamenteuse |
| EP2806742B1 (fr) * | 2012-01-26 | 2019-03-27 | TherapeuticsMD, Inc. | Thérapies transdermiques de remplacement d'hormone |
| WO2013130535A1 (fr) * | 2012-02-27 | 2013-09-06 | Newgen Biopharma Corporation | Administration locale de nano-formulations hormonale et non hormonale, procédés pour leur fabrication et leur utilisation |
-
2014
- 2014-10-22 MX MX2016005092A patent/MX2016005092A/es unknown
- 2014-10-22 CA CA2926342A patent/CA2926342A1/fr active Pending
- 2014-10-22 WO PCT/US2014/061811 patent/WO2015073177A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| MX2016005092A (es) | 2016-08-17 |
| WO2015073177A8 (fr) | 2016-07-07 |
| WO2015073177A1 (fr) | 2015-05-21 |
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