CA2923484C - Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors - Google Patents
Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors Download PDFInfo
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- CA2923484C CA2923484C CA2923484A CA2923484A CA2923484C CA 2923484 C CA2923484 C CA 2923484C CA 2923484 A CA2923484 A CA 2923484A CA 2923484 A CA2923484 A CA 2923484A CA 2923484 C CA2923484 C CA 2923484C
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- sepsis
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Landscapes
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| EP13183519 | 2013-09-09 | ||
| EP13183519.1 | 2013-09-09 | ||
| EP14151979 | 2014-01-21 | ||
| EP14151979.3 | 2014-01-21 | ||
| PCT/EP2014/069088 WO2015032945A1 (en) | 2013-09-09 | 2014-09-08 | Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors |
Publications (2)
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| CA2923484A1 CA2923484A1 (en) | 2015-03-12 |
| CA2923484C true CA2923484C (en) | 2022-09-06 |
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| US (1) | US9856228B2 (enExample) |
| EP (1) | EP3044214B1 (enExample) |
| JP (1) | JP6408008B2 (enExample) |
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| AU2014317048B2 (en) | 2013-09-09 | 2018-05-10 | Neuprozyme Therapeutics ApS | Peptidyl nitril compounds as dipeptidyl peptidase I inhibitors |
| NO2699580T3 (enExample) | 2014-01-24 | 2018-02-24 | ||
| AU2016227618B2 (en) | 2015-03-05 | 2020-06-04 | Neuprozyme Therapeutics ApS | Peptidyl nitril compounds as dipeptidyl peptidase I inhibitors |
| CN107690429B (zh) | 2015-04-07 | 2022-02-25 | Ela制药有限公司 | 用于治疗和/或预防细胞或组织坏死的组合物，其特异性靶向组织蛋白酶c和/或cela1和/或cela3a和/或与其结构相关的酶 |
| SI3758708T1 (sl) | 2018-03-01 | 2025-04-30 | Astrazeneca Ab | Farmacevtski sestavki, ki vsebujejo (2S)-{(1S)-1-ciano-2-[4-(3-metil-2-okso-2,3-dihidro-1,3-benzoksazol-5-il)fenil]etil}-1,4-oksazepan-2-karboksamid |
| AU2019306532A1 (en) | 2018-07-17 | 2021-03-04 | Insmed Incorporated | Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides for treating Lupus Nephritis |
| US20230310453A1 (en) | 2020-07-20 | 2023-10-05 | Insmed, Inc. | Methods for extracting neutrophil serine proteases and treating dipeptidyl peptidase 1-mediated conditions |
| KR20250022023A (ko) | 2022-06-13 | 2025-02-14 | 알리벡시스 가부시키가이샤 | 아자사이클로알킬카보닐 환상 아민 화합물 |
| CN120584108A (zh) | 2023-01-06 | 2025-09-02 | 英斯梅德股份有限公司 | 新型可逆dpp1抑制剂及其用途 |
| WO2025162472A1 (en) * | 2024-01-31 | 2025-08-07 | Insmed Incorporated | Linear dipeptidyl peptidase 1 inhibitors and uses thereof |
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| KR100903499B1 (ko) | 2007-12-27 | 2009-06-18 | 엔에이치엔비즈니스플랫폼 주식회사 | 검색 의도 분류에 따른 광고 제공 방법 및 상기 방법을수행하기 위한 시스템 |
| CN102574830A (zh) * | 2009-05-07 | 2012-07-11 | 阿斯利康(瑞典)有限公司 | 取代的1-氰基乙基杂环基甲酰胺化合物750 |
| WO2010142985A1 (en) | 2009-06-10 | 2010-12-16 | Astrazeneca Ab | Substituted n-[1-cyano-2-(phenyl)ethyl]piperidin-2-ylcarboxmide compounds 761 |
| WO2011154677A1 (en) | 2010-06-09 | 2011-12-15 | Astrazeneca Ab | Substituted n-[1-cyano-2-(phenyl)ethyl] 1-aminocycloalk-1-ylcarboxamide compounds - 760 |
| WO2012119941A1 (en) * | 2011-03-04 | 2012-09-13 | Prozymex A/S | Peptidyl nitrilcompounds as peptidase inhibitors |
| WO2012130299A1 (en) | 2011-03-30 | 2012-10-04 | Prozymex A/S | Peptidase inhibitors |
| US8999975B2 (en) * | 2011-09-19 | 2015-04-07 | Boehringer Ingelheim International Gmbh | Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C |
| AU2014317048B2 (en) | 2013-09-09 | 2018-05-10 | Neuprozyme Therapeutics ApS | Peptidyl nitril compounds as dipeptidyl peptidase I inhibitors |
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Also Published As
| Publication number | Publication date |
|---|---|
| SG11201601150WA (en) | 2016-03-30 |
| EP3044214B1 (en) | 2017-08-09 |
| NZ718128A (en) | 2021-04-30 |
| EA029030B1 (ru) | 2018-01-31 |
| US20160207900A1 (en) | 2016-07-21 |
| AU2014317048B2 (en) | 2018-05-10 |
| US9856228B2 (en) | 2018-01-02 |
| EA201690561A1 (ru) | 2016-07-29 |
| CA2923484A1 (en) | 2015-03-12 |
| WO2015032945A1 (en) | 2015-03-12 |
| AU2014317048A1 (en) | 2016-04-07 |
| DK3044214T3 (da) | 2017-11-13 |
| WO2015032943A1 (en) | 2015-03-12 |
| CN105612149A (zh) | 2016-05-25 |
| EP3044214A1 (en) | 2016-07-20 |
| JP6408008B2 (ja) | 2018-10-17 |
| JP2016529306A (ja) | 2016-09-23 |
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