CA2912766C - Nanostructured spore carrier - Google Patents
Nanostructured spore carrier Download PDFInfo
- Publication number
- CA2912766C CA2912766C CA2912766A CA2912766A CA2912766C CA 2912766 C CA2912766 C CA 2912766C CA 2912766 A CA2912766 A CA 2912766A CA 2912766 A CA2912766 A CA 2912766A CA 2912766 C CA2912766 C CA 2912766C
- Authority
- CA
- Canada
- Prior art keywords
- spore
- spore carrier
- spores
- substrate
- silica
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 135
- 239000000758 substrate Substances 0.000 claims abstract description 70
- 239000002105 nanoparticle Substances 0.000 claims abstract description 53
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 52
- 239000000090 biomarker Substances 0.000 claims abstract description 41
- 238000000034 method Methods 0.000 claims description 41
- -1 polypropylene Polymers 0.000 claims description 18
- 239000004743 Polypropylene Substances 0.000 claims description 17
- 239000002253 acid Substances 0.000 claims description 11
- 229920001155 polypropylene Polymers 0.000 claims description 9
- 239000011859 microparticle Substances 0.000 claims description 8
- 239000011230 binding agent Substances 0.000 claims description 6
- 241000193385 Geobacillus stearothermophilus Species 0.000 claims description 5
- 229920000728 polyester Polymers 0.000 claims description 4
- 241000193410 Bacillus atrophaeus Species 0.000 claims description 3
- 239000000969 carrier Substances 0.000 abstract description 17
- 230000001954 sterilising effect Effects 0.000 description 52
- 238000004659 sterilization and disinfection Methods 0.000 description 52
- 238000000576 coating method Methods 0.000 description 44
- 239000011248 coating agent Substances 0.000 description 40
- 239000006185 dispersion Substances 0.000 description 39
- 230000008569 process Effects 0.000 description 24
- 239000007787 solid Substances 0.000 description 23
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 22
- 239000007788 liquid Substances 0.000 description 18
- 239000000203 mixture Substances 0.000 description 17
- 229920000139 polyethylene terephthalate Polymers 0.000 description 16
- 239000005020 polyethylene terephthalate Substances 0.000 description 16
- 239000000463 material Substances 0.000 description 13
- 239000002245 particle Substances 0.000 description 12
- 239000008119 colloidal silica Substances 0.000 description 11
- 235000015097 nutrients Nutrition 0.000 description 11
- 229920000297 Rayon Polymers 0.000 description 10
- 239000011521 glass Substances 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 230000004071 biological effect Effects 0.000 description 9
- 230000008859 change Effects 0.000 description 9
- 238000005259 measurement Methods 0.000 description 9
- 239000002964 rayon Substances 0.000 description 9
- 230000003068 static effect Effects 0.000 description 9
- 229910001868 water Inorganic materials 0.000 description 9
- 229920002799 BoPET Polymers 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 6
- 238000004891 communication Methods 0.000 description 6
- 239000000835 fiber Substances 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 239000002609 medium Substances 0.000 description 6
- 239000000123 paper Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000011534 incubation Methods 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 230000004044 response Effects 0.000 description 5
- 229910052708 sodium Inorganic materials 0.000 description 5
- 239000011734 sodium Substances 0.000 description 5
- 230000003746 surface roughness Effects 0.000 description 5
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000003708 ampul Substances 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 4
- 238000000151 deposition Methods 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 230000035784 germination Effects 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 230000036512 infertility Effects 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 239000004417 polycarbonate Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 101000608720 Helianthus annuus 10 kDa late embryogenesis abundant protein Proteins 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 108010028144 alpha-Glucosidases Proteins 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000012876 carrier material Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000000975 dye Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 229920000915 polyvinyl chloride Polymers 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 2
- FRPHFZCDPYBUAU-UHFFFAOYSA-N Bromocresolgreen Chemical compound CC1=C(Br)C(O)=C(Br)C=C1C1(C=2C(=C(Br)C(O)=C(Br)C=2)C)C2=CC=CC=C2S(=O)(=O)O1 FRPHFZCDPYBUAU-UHFFFAOYSA-N 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- 241000626621 Geobacillus Species 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 238000004630 atomic force microscopy Methods 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- ABIUHPWEYMSGSR-UHFFFAOYSA-N bromocresol purple Chemical compound BrC1=C(O)C(C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C=C(Br)C(O)=C(C)C=2)=C1 ABIUHPWEYMSGSR-UHFFFAOYSA-N 0.000 description 2
- UDSAIICHUKSCKT-UHFFFAOYSA-N bromophenol blue Chemical compound C1=C(Br)C(O)=C(Br)C=C1C1(C=2C=C(Br)C(O)=C(Br)C=2)C2=CC=CC=C2S(=O)(=O)O1 UDSAIICHUKSCKT-UHFFFAOYSA-N 0.000 description 2
- NUHCTOLBWMJMLX-UHFFFAOYSA-N bromothymol blue Chemical compound BrC1=C(O)C(C(C)C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C(=C(Br)C(O)=C(C(C)C)C=2)C)=C1C NUHCTOLBWMJMLX-UHFFFAOYSA-N 0.000 description 2
- WWAABJGNHFGXSJ-UHFFFAOYSA-N chlorophenol red Chemical compound C1=C(Cl)C(O)=CC=C1C1(C=2C=C(Cl)C(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 WWAABJGNHFGXSJ-UHFFFAOYSA-N 0.000 description 2
- 239000008199 coating composition Substances 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 229910001882 dioxygen Inorganic materials 0.000 description 2
- XJRPTMORGOIMMI-UHFFFAOYSA-N ethyl 2-amino-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate Chemical compound CCOC(=O)C=1SC(N)=NC=1C(F)(F)F XJRPTMORGOIMMI-UHFFFAOYSA-N 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000002086 nanomaterial Substances 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 238000009832 plasma treatment Methods 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920000098 polyolefin Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- YUDPTGPSBJVHCN-JZYAIQKZSA-N 4-Methylumbelliferyl-alpha-D-glucopyranoside Chemical compound C1=CC=2C(C)=CC(=O)OC=2C=C1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YUDPTGPSBJVHCN-JZYAIQKZSA-N 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 229910021532 Calcite Inorganic materials 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 230000004568 DNA-binding Effects 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 101000618467 Hypocrea jecorina (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30) Endo-1,4-beta-xylanase 2 Proteins 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- 229920004142 LEXAN™ Polymers 0.000 description 1
- 239000004418 Lexan Substances 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 230000004570 RNA-binding Effects 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- BOTDANWDWHJENH-UHFFFAOYSA-N Tetraethyl orthosilicate Chemical compound CCO[Si](OCC)(OCC)OCC BOTDANWDWHJENH-UHFFFAOYSA-N 0.000 description 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229920006378 biaxially oriented polypropylene Polymers 0.000 description 1
- 239000011127 biaxially oriented polypropylene Substances 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 238000003490 calendering Methods 0.000 description 1
- 239000007894 caplet Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 229920000891 common polymer Polymers 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000003851 corona treatment Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 230000005670 electromagnetic radiation Effects 0.000 description 1
- 238000000572 ellipsometry Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012869 germination medium Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000007759 kiss coating Methods 0.000 description 1
- 231100000225 lethality Toxicity 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- CEQFOVLGLXCDCX-WUKNDPDISA-N methyl red Chemical compound C1=CC(N(C)C)=CC=C1\N=N\C1=CC=CC=C1C(O)=O CEQFOVLGLXCDCX-WUKNDPDISA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000001282 organosilanes Chemical class 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000003348 petrochemical agent Substances 0.000 description 1
- 239000007793 ph indicator Substances 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920000307 polymer substrate Polymers 0.000 description 1
- 239000012462 polypropylene substrate Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 150000004756 silanes Chemical class 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000012756 surface treatment agent Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 239000012808 vapor phase Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/22—Testing for sterility conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Laminated Bodies (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361825854P | 2013-05-21 | 2013-05-21 | |
| US61/825,854 | 2013-05-21 | ||
| PCT/US2014/037829 WO2014189716A1 (en) | 2013-05-21 | 2014-05-13 | Nanostructured spore carrier |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2912766A1 CA2912766A1 (en) | 2014-11-27 |
| CA2912766C true CA2912766C (en) | 2021-09-07 |
Family
ID=50896573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2912766A Active CA2912766C (en) | 2013-05-21 | 2014-05-13 | Nanostructured spore carrier |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9650661B2 (enExample) |
| EP (1) | EP2999794B1 (enExample) |
| JP (1) | JP6483665B2 (enExample) |
| CN (1) | CN105229163B (enExample) |
| BR (1) | BR112015029292B1 (enExample) |
| CA (1) | CA2912766C (enExample) |
| WO (1) | WO2014189716A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105229163B (zh) * | 2013-05-21 | 2023-03-17 | 3M创新有限公司 | 纳米结构化孢子载体 |
| US10907126B2 (en) | 2016-03-01 | 2021-02-02 | Asp Global Manufacturing Gmbh | Self-contained biological indicator |
| WO2018013668A1 (en) | 2016-07-12 | 2018-01-18 | Alexander Poltorak | System and method for maintaining efficiency of a heat sink |
| US11242505B2 (en) | 2017-01-03 | 2022-02-08 | Asp Global Manufacturing Gmbh | Self-contained biological indicator |
| US11053534B2 (en) | 2017-06-30 | 2021-07-06 | Asp Global Manufacturing Gmbh | Systems and methods for confirming activation of biological indicators |
| US20190106726A1 (en) * | 2017-10-11 | 2019-04-11 | American Sterilizer Company | Biological indicator |
| US11248250B2 (en) | 2017-12-01 | 2022-02-15 | Asp Global Manufacturing Gmb | Self-contained biological indicator |
| WO2019123156A1 (en) * | 2017-12-19 | 2019-06-27 | 3M Innovative Properties Company | Compositions and methods to detect microorganisms |
| EP3844126A1 (en) * | 2018-08-31 | 2021-07-07 | Corning Incorporated | Methods of making honeycomb bodies having inorganic filtration deposits |
| WO2020115661A1 (en) | 2018-12-06 | 2020-06-11 | 3M Innovative Properties Company | FLUORINATED 4' ALKYLUMBELLIFERYL α-D-GLUCOPYRANOSIDES, BIOLOGICAL STERILIZATION INDICATORS INCLUDING THE SAME AND METHODS OF USING THE SAME |
| WO2020136613A1 (en) * | 2018-12-27 | 2020-07-02 | 3M Innovative Properties Company | Instant read-out biological indicator with growth confirmation |
| WO2020136608A1 (en) * | 2018-12-27 | 2020-07-02 | 3M Innovative Properties Company | Instant read-out biological indicator |
| US12486301B2 (en) | 2019-09-25 | 2025-12-02 | Solventum Intellectual Properties Company | 8-fluoro-4-alkylumbelliferyl α-D-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process |
| CN115315522B (zh) * | 2020-03-17 | 2025-08-08 | 舒万诺知识产权公司 | 用于生物指示器生长指示的固定ph指示剂 |
| MX2023005304A (es) | 2020-11-10 | 2023-06-23 | Advanced Sterilization Products Inc | Rompeampollas para un indicador biologico. |
| US11603551B2 (en) | 2020-12-02 | 2023-03-14 | Steritec Products Mfg. Co., Inc. | Biological indicators, and systems and methods for determining efficacy of sterilization |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH219890A (de) | 1939-05-27 | 1942-03-15 | Jenaer Glaswerk Schott & Gen | Verfahren zur Herstellung einer oder mehrerer übereinanderliegender, dünner, widerstandsfähiger Schichten auf festen Gegenständen. |
| US2432484A (en) | 1943-03-12 | 1947-12-09 | American Optical Corp | Reflection reducing coating having a gradually increasing index of refraction |
| US2601123A (en) | 1947-04-05 | 1952-06-17 | American Optical Corp | Composition for reducing the reflection of light |
| US2536764A (en) | 1947-04-05 | 1951-01-02 | American Optical Corp | Method of forming a reflection reducing coating |
| US3846242A (en) | 1967-07-14 | 1974-11-05 | Sybron Corp | Biological sterility indicator and method for using same |
| CA1275208C (en) | 1985-01-25 | 1990-10-16 | Roger W. Lange | Silica coating |
| US4717661A (en) | 1986-01-21 | 1988-01-05 | Castle Company | Biological indicator for sterilization processes |
| US5039561A (en) | 1986-08-25 | 1991-08-13 | Minnesota Mining And Manufacturing Company | Method for preparing an article having surface layer of uniformly oriented, crystalline, organic microstructures |
| US5252484A (en) | 1988-11-29 | 1993-10-12 | Minnesota Mining And Manufacturing Company | Rapid read-out biological indicator |
| US5073488A (en) | 1988-11-29 | 1991-12-17 | Minnesota Mining And Manufacturing Company | Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator |
| US5223401A (en) | 1988-11-29 | 1993-06-29 | Minnesota Mining And Manufacturing Company | Rapid read-out sterility indicator |
| US5739004A (en) | 1993-05-20 | 1998-04-14 | Minnesota Mining And Manufacturing Company | Biological sterilization indication for use with or without test pack materials or devices |
| US5585186A (en) | 1994-12-12 | 1996-12-17 | Minnesota Mining And Manufacturing Company | Coating composition having anti-reflective, and anti-fogging properties |
| US5795730A (en) | 1995-02-15 | 1998-08-18 | Minnesota Mining And Manufacturing Company | Rapid read-out biological indicator |
| US5753373A (en) | 1995-12-21 | 1998-05-19 | Minnesota Mining And Manufacturing Company | Coating composition having anti-reflective and anti-fogging properties |
| US6040053A (en) | 1996-07-19 | 2000-03-21 | Minnesota Mining And Manufacturing Company | Coating composition having anti-reflective and anti-fogging properties |
| DE19818956A1 (de) | 1997-05-23 | 1998-11-26 | Huels Chemische Werke Ag | Materialien mit mikrorauhen, bakterienabweisenden Oberflächen |
| US6420622B1 (en) | 1997-08-01 | 2002-07-16 | 3M Innovative Properties Company | Medical article having fluid control film |
| EP1089880B1 (en) | 1998-04-29 | 2004-02-11 | 3M Innovative Properties Company | Receptor sheet for inkjet printing having an embossed surface |
| US7309519B2 (en) | 1998-10-05 | 2007-12-18 | 3M Innovative Properties Company | Friction control articles for healthcare applications |
| US6762339B1 (en) | 1999-05-21 | 2004-07-13 | 3M Innovative Properties Company | Hydrophilic polypropylene fibers having antimicrobial activity |
| US6326723B1 (en) | 1999-05-25 | 2001-12-04 | Intel Corporation | Display screen |
| US7223364B1 (en) | 1999-07-07 | 2007-05-29 | 3M Innovative Properties Company | Detection article having fluid control film |
| DE19950452A1 (de) | 1999-10-20 | 2001-04-26 | Creavis Tech & Innovation Gmbh | Strukturierte Oberflächen mit zelladhäsions- und zellproliferationshemmenden Eigenschaften |
| US7476533B2 (en) | 2002-04-19 | 2009-01-13 | Adhesives Research, Inc. | Diagnostic devices for use in the assaying of biological fluids |
| US20030129087A1 (en) * | 2001-06-13 | 2003-07-10 | The Regents Of The University Of California | Ordered adsorbed layers of nano particulate materials on structured nano-laminate templates |
| US7140812B2 (en) | 2002-05-29 | 2006-11-28 | 3M Innovative Properties Company | Diamond tool with a multi-tipped diamond |
| US20030235678A1 (en) | 2002-06-25 | 2003-12-25 | Graham Paul D. | Complex microstructure film |
| US20030235677A1 (en) | 2002-06-25 | 2003-12-25 | 3M Innovative Properties Company | Complex microstructure film |
| DE60333373D1 (de) | 2002-08-15 | 2010-08-26 | Fujifilm Corp | Antireflexfilm, polarisationsplatte und bildanzeigeeinrichtung |
| ATE346852T1 (de) | 2003-08-21 | 2006-12-15 | 3M Innovative Properties Co | Perfluorpolyetheramidgebundene phosphonate, phosphate und derivate davon |
| US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| WO2005068399A1 (en) | 2004-01-15 | 2005-07-28 | Newsouth Innovations Pty Limited | Method of making a surface hydrophobic |
| US20080090010A1 (en) | 2004-01-15 | 2008-04-17 | Newsouth Innovations Pty Limited | Hydrophobic Coating Composition |
| US7143709B2 (en) | 2004-02-17 | 2006-12-05 | University Of Florida Research Foundation, Inc. | Surface topography for non-toxic bioadhesion control |
| US9016221B2 (en) | 2004-02-17 | 2015-04-28 | University Of Florida Research Foundation, Inc. | Surface topographies for non-toxic bioadhesion control |
| US7650848B2 (en) | 2004-02-17 | 2010-01-26 | University Of Florida Research Foundation, Inc. | Surface topographies for non-toxic bioadhesion control |
| MXPA06013421A (es) * | 2004-05-18 | 2007-03-01 | Australian Nuclear Science Tec | Birreactor de membrana. |
| US7258731B2 (en) | 2004-07-27 | 2007-08-21 | Ut Battelle, Llc | Composite, nanostructured, super-hydrophobic material |
| US8198326B2 (en) | 2004-09-07 | 2012-06-12 | 3M Innovative Properties Company | Phenolic antiseptic compositions and methods of use |
| US20060051384A1 (en) | 2004-09-07 | 2006-03-09 | 3M Innovative Properties Company | Antiseptic compositions and methods of use |
| US9028852B2 (en) | 2004-09-07 | 2015-05-12 | 3M Innovative Properties Company | Cationic antiseptic compositions and methods of use |
| US7569359B2 (en) | 2004-10-14 | 2009-08-04 | American Sterilizer Company | Indicator device having an active agent encapsulated in an electrospun nanofiber |
| US7416883B2 (en) | 2005-05-24 | 2008-08-26 | Steris Inc. | Biological indicator |
| US20070134784A1 (en) | 2005-12-09 | 2007-06-14 | Halverson Kurt J | Microreplicated microarrays |
| US20070141305A1 (en) | 2005-12-21 | 2007-06-21 | Toshihiro Kasai | Superhydrophobic coating |
| US20070231542A1 (en) | 2006-04-03 | 2007-10-04 | General Electric Company | Articles having low wettability and high light transmission |
| JP2008002007A (ja) | 2006-06-21 | 2008-01-10 | Daiwabo Co Ltd | ナノ粒子担持材料およびその製造方法 |
| US8354160B2 (en) | 2006-06-23 | 2013-01-15 | 3M Innovative Properties Company | Articles having durable hydrophobic surfaces |
| US20080176263A1 (en) | 2006-12-07 | 2008-07-24 | University Of Florida Research Foundation, Inc. | Materials and Methods for Efficient and Accurate Detection of Analytes |
| CN107050490B (zh) * | 2008-05-05 | 2020-07-07 | 3M创新有限公司 | 灭菌过程验证装置和方法 |
| AU2009257361A1 (en) | 2008-06-12 | 2009-12-17 | 3M Innovative Properties Company | Biocompatible hydrophilic compositions |
| WO2009158046A1 (en) | 2008-06-27 | 2009-12-30 | The Board Of Trustees Of The University Of Illinois | Polymer composite formulations from poly(vinylidine fluoride) (pvdf) and cyanoacrylates (ca) and methods for use in large-area applications |
| US20100035039A1 (en) | 2008-08-07 | 2010-02-11 | 3M Innovative Properties Company | Acicular silica coating for enhanced hydrophilicity/transmittivity |
| US8173388B2 (en) * | 2008-09-30 | 2012-05-08 | American Sterilizer Company | Self-contained biological indicator |
| US20100092765A1 (en) | 2008-10-10 | 2010-04-15 | 3M Innovative Properties Company | Silica coating for enhanced hydrophilicity |
| KR20120097517A (ko) | 2009-11-18 | 2012-09-04 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 보호 코팅 및 이의 제조 및 이용 방법 |
| BR112012030011A2 (pt) | 2010-05-25 | 2016-08-02 | 3M Innovative Properties Co | revestimentos antimicrobianos |
| CN103180059A (zh) | 2010-10-28 | 2013-06-26 | 3M创新有限公司 | 用于降低细菌粘附力的工程化表面 |
| WO2012061212A1 (en) * | 2010-11-01 | 2012-05-10 | 3M Innovative Properties Company | Method of detecting a biological activity |
| WO2012078374A2 (en) | 2010-12-06 | 2012-06-14 | 3M Innovative Properties Company | Microorganism concentration process and device |
| EP2773706B1 (en) * | 2011-11-02 | 2019-09-25 | 3M Innovative Properties Company | Hydrophilic fluid transport device |
| US20150017386A1 (en) * | 2012-02-01 | 2015-01-15 | 3M Innovative Properties Company | Nanostructured materials and methods of making the same |
| CN105229163B (zh) * | 2013-05-21 | 2023-03-17 | 3M创新有限公司 | 纳米结构化孢子载体 |
-
2014
- 2014-05-13 CN CN201480029222.4A patent/CN105229163B/zh active Active
- 2014-05-13 US US14/891,760 patent/US9650661B2/en active Active
- 2014-05-13 JP JP2016515355A patent/JP6483665B2/ja active Active
- 2014-05-13 WO PCT/US2014/037829 patent/WO2014189716A1/en not_active Ceased
- 2014-05-13 BR BR112015029292-5A patent/BR112015029292B1/pt active IP Right Grant
- 2014-05-13 EP EP14728785.8A patent/EP2999794B1/en active Active
- 2014-05-13 CA CA2912766A patent/CA2912766C/en active Active
-
2017
- 2017-04-11 US US15/484,781 patent/US10059977B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105229163A (zh) | 2016-01-06 |
| EP2999794B1 (en) | 2018-03-28 |
| CN105229163B (zh) | 2023-03-17 |
| JP2016528876A (ja) | 2016-09-23 |
| US10059977B2 (en) | 2018-08-28 |
| BR112015029292A2 (pt) | 2017-07-25 |
| JP6483665B2 (ja) | 2019-03-13 |
| WO2014189716A1 (en) | 2014-11-27 |
| US20160083771A1 (en) | 2016-03-24 |
| CA2912766A1 (en) | 2014-11-27 |
| US9650661B2 (en) | 2017-05-16 |
| US20170218428A1 (en) | 2017-08-03 |
| BR112015029292B1 (pt) | 2022-06-14 |
| EP2999794A1 (en) | 2016-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10059977B2 (en) | Biological sterilization indicator | |
| Page et al. | Titania and silver–titania composite films on glass—potent antimicrobial coatings | |
| US20060194037A1 (en) | Flexible, breathable polymer film and method for production thereof | |
| EP2773706B1 (en) | Hydrophilic fluid transport device | |
| Stancu et al. | Plasma functionalization of carbon nanowalls and its effect on attachment of fibroblast-like cells | |
| CN102782474A (zh) | 智能颜料和塑料 | |
| CN105073146A (zh) | 用于监测低温灭菌过程的生物指示器 | |
| EP1153999B1 (en) | Photocatalytic coating composition and product having thin photocatalytic film | |
| WO2012050639A1 (en) | Antibiofilm nanoporous nanostructures and method to produce same | |
| JP7719193B2 (ja) | 一酸化窒素の存在を検出するための装置と方法 | |
| Alexandrovskaya et al. | A comprehensive study of the resistance to biofouling of different polymers for optical oxygen sensors. The advantage of the novel fluorinated composite based on core-dye-shell structure | |
| CN107109467B (zh) | 含有荧光素的基底和包括基底的监测装置 | |
| US20150241412A1 (en) | Self-assembled nanostructured sensors and methods thereof | |
| Applebee et al. | Multi-component liquid-infused systems: a new approach to functional coatings | |
| Subrahmanyam et al. | Efficacy of titanium doped-indium tin oxide (Ti/TiO 2–ITO) films in rapid oxygen generation under photocatalysis and their suitability for bio-medical application | |
| WO2020128956A2 (en) | Sterilization chemical indicator | |
| Li et al. | Tannic Acid–Iron Assembly Films for Electrochemical Sensing of Dopamine | |
| JP7811308B2 (ja) | 滅菌化学インジケータ | |
| Seifunnisha et al. | Fabrication of Superhydrophobic and Photocatalytic Self‐Cleaning Thin Film Using Polystyrene with Zno | |
| JP2006061792A (ja) | 光触媒構造 | |
| CA3139021A1 (en) | Chemical hydrogen peroxide indicator | |
| EP2929323B1 (en) | Individually and flexibly deployable target-analyte sensitive particulate probes and method of making and using | |
| JP2013169532A (ja) | 光触媒性能評価方法 | |
| FR3115181A1 (fr) | Film multicouche auto-desinfectant comprenant une couche d'oxyde semi-conducteur polycristallin photocatalytique | |
| TW200927934A (en) | Bio-detecting element and preparing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190513 |