CA2895106C - Anoikis resistant placental stem cells and uses thereof - Google Patents

Anoikis resistant placental stem cells and uses thereof Download PDF

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Publication number
CA2895106C
CA2895106C CA2895106A CA2895106A CA2895106C CA 2895106 C CA2895106 C CA 2895106C CA 2895106 A CA2895106 A CA 2895106A CA 2895106 A CA2895106 A CA 2895106A CA 2895106 C CA2895106 C CA 2895106C
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placental stem
arpscs
cells
stem cells
gene
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French (fr)
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CA2895106A1 (en
Inventor
Xiaokui Zhang
Stewart Abbot
Vanessa Voskinarian-Berse
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Celularity Inc
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Celularity Inc
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141—MicroRNAs, miRNAs
    • C—CHEMISTRY; METALLURGY
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/65—MicroRNA
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    • C12N2510/00—Genetically modified cells

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
CA2895106A 2012-12-14 2013-12-13 Anoikis resistant placental stem cells and uses thereof Active CA2895106C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737498P 2012-12-14 2012-12-14
US61/737,498 2012-12-14
PCT/US2013/074892 WO2014093753A1 (en) 2012-12-14 2013-12-13 Anoikis resistant placental stem cells and uses thereof

Publications (2)

Publication Number Publication Date
CA2895106A1 CA2895106A1 (en) 2014-06-19
CA2895106C true CA2895106C (en) 2023-01-24

Family

ID=50934980

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2895106A Active CA2895106C (en) 2012-12-14 2013-12-13 Anoikis resistant placental stem cells and uses thereof

Country Status (7)

Country Link
US (1) US20150307879A1 (https=)
EP (2) EP2938196B1 (https=)
JP (5) JP2016502844A (https=)
CN (2) CN113481164A (https=)
AU (1) AU2013359076A1 (https=)
CA (1) CA2895106C (https=)
WO (1) WO2014093753A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10329529B2 (en) * 2013-03-14 2019-06-25 Celularity, Inc. Enhanced placental stem cells and uses thereof
CN107475419A (zh) * 2017-09-22 2017-12-15 浙江大学 Kndc1基因及其表达产物在卵巢癌检测中的应用
CN110129321B (zh) * 2019-07-08 2021-10-15 江苏医药职业学院 降低LSG1基因表达的siRNA、重组载体及其应用

Family Cites Families (22)

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US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US5190556A (en) 1991-03-19 1993-03-02 O.B. Tech, Inc. Cord cutter sampler
US5552267A (en) 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5372581A (en) 1993-07-21 1994-12-13 Minneapolis Children's Services Corporation Method and apparatus for placental blood collection
JP2002542349A (ja) 1999-04-16 2002-12-10 ダブリューエム・マーシュ・ライス・ユニバーシティー ポリ（プロピレンフマラート）−ジアクリレートマクロマーで交差結合された生体分解性のポリ（プロピレンフマラート）ネットワーク
US6355699B1 (en) 1999-06-30 2002-03-12 Ethicon, Inc. Process for manufacturing biomedical foams
EP2305795B1 (en) 2000-12-06 2019-07-03 Celularity, Inc. Method of collecting placental stem cells
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
EP2316918B1 (en) 2001-02-14 2015-07-01 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
ES2432493T3 (es) 2001-02-14 2013-12-03 Anthrogenesis Corporation Placenta de mamífero post-parto, su uso y células madre de la misma
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
NZ597304A (en) 2005-10-13 2013-06-28 Anthrogenesis Corp Immunomodulation using placental stem cells
ZA200804717B (en) 2005-12-29 2010-02-24 Anthrogenesis Corp Improved composition for collecting and preserving a placental stem cells and methods of using the composition
PL2471907T3 (pl) * 2005-12-29 2019-07-31 Celularity, Inc. Populacje komórek macierzystych łożyska
US20100305188A1 (en) * 2007-10-03 2010-12-02 Kyowa Hakko Kirin Co., Ltd. Nucleic acid capable of regulating the proliferation of cell
CN101862315A (zh) * 2009-04-17 2010-10-20 中国医学科学院血液病医院（血液学研究所） 双取代苯基双胍诱导恶性肿瘤细胞失巢凋亡的用途
CA2778005A1 (en) * 2009-10-26 2011-05-12 Abbott Laboratories Detection of chromosomal abnormalities associated with prognosis of non small cell lung cancer
CA2779310C (en) * 2009-10-31 2021-11-30 New World Laboratories Inc. Methods for reprogramming cells and uses thereof
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US20120171161A1 (en) * 2010-12-30 2012-07-05 Sascha Abramson Compositions comprising placental stem cells and platelet rich plasma, and methods of use thereof
WO2012092485A1 (en) * 2010-12-31 2012-07-05 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
US10329529B2 (en) * 2013-03-14 2019-06-25 Celularity, Inc. Enhanced placental stem cells and uses thereof

Also Published As

Publication number Publication date
NZ709113A (en) 2020-11-27
CN105283075A (zh) 2016-01-27
EP2938196A1 (en) 2015-11-04
CN113481164A (zh) 2021-10-08
JP2021045133A (ja) 2021-03-25
JP2024153631A (ja) 2024-10-29
JP2022160451A (ja) 2022-10-19
AU2013359076A1 (en) 2015-07-02
EP2938196B1 (en) 2019-04-03
CA2895106A1 (en) 2014-06-19
JP2019068814A (ja) 2019-05-09
EP2938196A4 (en) 2016-10-26
EP3556215A1 (en) 2019-10-23
US20150307879A1 (en) 2015-10-29
WO2014093753A1 (en) 2014-06-19
JP2016502844A (ja) 2016-02-01

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