CA2890215A1 - Non-invasive brain temperature regulating devices for enhancing sleep - Google Patents
Non-invasive brain temperature regulating devices for enhancing sleep Download PDFInfo
- Publication number
- CA2890215A1 CA2890215A1 CA2890215A CA2890215A CA2890215A1 CA 2890215 A1 CA2890215 A1 CA 2890215A1 CA 2890215 A CA2890215 A CA 2890215A CA 2890215 A CA2890215 A CA 2890215A CA 2890215 A1 CA2890215 A1 CA 2890215A1
- Authority
- CA
- Canada
- Prior art keywords
- applicator
- subject
- thermal
- phase change
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000007958 sleep Effects 0.000 title claims abstract description 75
- 230000002708 enhancing effect Effects 0.000 title claims abstract description 17
- 230000001105 regulatory effect Effects 0.000 title claims description 13
- 210000004556 brain Anatomy 0.000 title description 17
- 239000012782 phase change material Substances 0.000 claims abstract description 98
- 238000000034 method Methods 0.000 claims abstract description 42
- 210000005153 frontal cortex Anatomy 0.000 claims abstract description 31
- 238000012546 transfer Methods 0.000 claims description 79
- 210000003128 head Anatomy 0.000 claims description 60
- 239000000463 material Substances 0.000 claims description 51
- 230000007704 transition Effects 0.000 claims description 35
- 210000001061 forehead Anatomy 0.000 claims description 26
- 239000002775 capsule Substances 0.000 claims description 18
- 238000004891 communication Methods 0.000 claims description 12
- 239000011159 matrix material Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 239000004020 conductor Substances 0.000 claims description 4
- 239000012188 paraffin wax Substances 0.000 claims description 3
- 238000001816 cooling Methods 0.000 abstract description 41
- 206010022437 insomnia Diseases 0.000 abstract description 21
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract description 19
- 230000033228 biological regulation Effects 0.000 abstract description 19
- 230000001965 increasing effect Effects 0.000 abstract description 10
- 208000012902 Nervous system disease Diseases 0.000 abstract description 5
- 208000025966 Neurological disease Diseases 0.000 abstract description 5
- 230000004622 sleep time Effects 0.000 abstract description 3
- 239000012071 phase Substances 0.000 description 39
- 210000002442 prefrontal cortex Anatomy 0.000 description 20
- 230000008859 change Effects 0.000 description 13
- 239000007787 solid Substances 0.000 description 12
- 238000010792 warming Methods 0.000 description 9
- 230000002360 prefrontal effect Effects 0.000 description 8
- 238000011282 treatment Methods 0.000 description 8
- 238000002135 phase contrast microscopy Methods 0.000 description 7
- 230000002459 sustained effect Effects 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 230000004060 metabolic process Effects 0.000 description 6
- 230000002618 waking effect Effects 0.000 description 6
- 230000002490 cerebral effect Effects 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 208000035475 disorder Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 210000004761 scalp Anatomy 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 206010062519 Poor quality sleep Diseases 0.000 description 4
- 206010041349 Somnolence Diseases 0.000 description 4
- 210000003710 cerebral cortex Anatomy 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 208000019116 sleep disease Diseases 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 208000032140 Sleepiness Diseases 0.000 description 3
- 210000003484 anatomy Anatomy 0.000 description 3
- 230000036757 core body temperature Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000013013 elastic material Substances 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000005338 heat storage Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000037321 sleepiness Effects 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
- 239000004753 textile Substances 0.000 description 3
- 208000010340 Sleep Deprivation Diseases 0.000 description 2
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 2
- 230000003542 behavioural effect Effects 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 230000001054 cortical effect Effects 0.000 description 2
- 230000004153 glucose metabolism Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000012774 insulation material Substances 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 239000000955 prescription drug Substances 0.000 description 2
- 238000005057 refrigeration Methods 0.000 description 2
- 230000037322 slow-wave sleep Effects 0.000 description 2
- 235000017281 sodium acetate Nutrition 0.000 description 2
- 239000001632 sodium acetate Substances 0.000 description 2
- 230000008023 solidification Effects 0.000 description 2
- 238000007711 solidification Methods 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- CEGXZKXILQSJHO-AKNDJLBFSA-N (3R,4S,5R)-3,4,5,6-tetrahydroxyhexan(18F)oyl fluoride Chemical compound [18F]C(=O)C[C@@H](O)[C@H](O)[C@H](O)CO CEGXZKXILQSJHO-AKNDJLBFSA-N 0.000 description 1
- QUAYLBGGFDRHGO-UHFFFAOYSA-N CCCCC[F]CC Chemical compound CCCCC[F]CC QUAYLBGGFDRHGO-UHFFFAOYSA-N 0.000 description 1
- 208000028698 Cognitive impairment Diseases 0.000 description 1
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 206010020674 Hypermetabolism Diseases 0.000 description 1
- 206010047141 Vasodilatation Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000037007 arousal Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000003925 brain function Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000009636 circadian regulation Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 208000010877 cognitive disease Diseases 0.000 description 1
- 238000009226 cognitive therapy Methods 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005496 eutectics Effects 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000003284 homeostatic effect Effects 0.000 description 1
- 230000002631 hypothermal effect Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 150000001247 metal acetylides Chemical class 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 150000004767 nitrides Chemical class 0.000 description 1
- 239000000820 nonprescription drug Substances 0.000 description 1
- 239000002667 nucleating agent Substances 0.000 description 1
- 230000006911 nucleation Effects 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000002600 positron emission tomography Methods 0.000 description 1
- 238000012802 pre-warming Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- -1 salt hydrates Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000003860 sleep quality Effects 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000011232 storage material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000000225 synapse Anatomy 0.000 description 1
- 230000000542 thalamic effect Effects 0.000 description 1
- 239000002470 thermal conductor Substances 0.000 description 1
- 230000001331 thermoregulatory effect Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M21/02—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0001—Body part
- A61F2007/0002—Head or parts thereof
- A61F2007/0007—Forehead, e.g. headbands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
- A61F2007/0063—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling
- A61F2007/0064—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling of gas
- A61F2007/0065—Causing evaporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0292—Compresses or poultices for effecting heating or cooling using latent heat produced or absorbed during phase change of materials, e.g. of super-cooled solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
- A61M2021/0066—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with heating or cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3646—General characteristics of the apparatus related to heating or cooling by heat accumulators, e.g. ice, sand
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Pain & Pain Management (AREA)
- Acoustics & Sound (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261727054P | 2012-11-15 | 2012-11-15 | |
| US61/727,054 | 2012-11-15 | ||
| US201361859161P | 2013-07-26 | 2013-07-26 | |
| US61/859,161 | 2013-07-26 | ||
| PCT/US2013/070251 WO2014078630A1 (en) | 2012-11-15 | 2013-11-15 | Non-invasive brain temperature regulating devices for enhancing sleep |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2890215A1 true CA2890215A1 (en) | 2014-05-22 |
Family
ID=50731711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2890215A Abandoned CA2890215A1 (en) | 2012-11-15 | 2013-11-15 | Non-invasive brain temperature regulating devices for enhancing sleep |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2919843A4 (enExample) |
| JP (1) | JP2016501074A (enExample) |
| AU (1) | AU2013344545A1 (enExample) |
| CA (1) | CA2890215A1 (enExample) |
| WO (1) | WO2014078630A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3024525B1 (en) * | 2013-07-26 | 2021-11-17 | EBB Therapeutics, Inc. | Apparatus and method for modulating sleep |
| US20170319815A1 (en) * | 2015-01-27 | 2017-11-09 | Ebb Therapeutics, Inc. | Method and apparatuses for modulating sleep by chemical activation of temperature receptors |
| US10004632B2 (en) | 2015-07-16 | 2018-06-26 | Slumber Science LLC | Devices, systems, and kits for regulating skin temperature for mammals |
| CA3104484A1 (en) * | 2018-06-19 | 2019-12-26 | Thermaquil, Inc. | Systems and methods for thermal blockade of nerves |
| US12370079B2 (en) | 2018-06-19 | 2025-07-29 | Thermaquil, Inc. | Apparatus and method for thermal blockade of nerves |
| US10695530B1 (en) | 2019-06-10 | 2020-06-30 | Slumber Science LLC | Methods, devices, systems, and kits for regulating skin temperature for mammals to induce and/or maintain sleep |
| KR102672546B1 (ko) * | 2021-09-22 | 2024-06-04 | 안영환 | 펜형 주사장치의 커버형 온도유지시스템 |
| JP2024098458A (ja) * | 2023-01-10 | 2024-07-23 | 富士電機株式会社 | 半導体装置 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4964402A (en) * | 1988-08-17 | 1990-10-23 | Royce Medical Company | Orthopedic device having gel pad with phase change material |
| US5274865A (en) * | 1992-11-25 | 1994-01-04 | Sanwa Life Cela Kabushiki Kaisha | Cooling device |
| US7744640B1 (en) * | 1999-08-11 | 2010-06-29 | Medical Products, Inc. | Thermal treatment garment and method of thermally treating body portions |
| AU2350300A (en) * | 1999-11-30 | 2001-06-12 | Procter & Gamble Company, The | Cooling pad |
| US6755852B2 (en) * | 2001-12-08 | 2004-06-29 | Charles A. Lachenbruch | Cooling body wrap with phase change material |
| JP4308561B2 (ja) * | 2002-10-15 | 2009-08-05 | 大阪瓦斯株式会社 | 冷却材 |
| EP1727503A1 (en) * | 2004-02-23 | 2006-12-06 | Aqueduct Medical, Inc. | Temperature-controllable device |
| US8425583B2 (en) * | 2006-04-20 | 2013-04-23 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia |
| EP2007334A1 (en) * | 2006-04-20 | 2008-12-31 | University of Pittsburgh | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders |
| US20100312317A1 (en) * | 2009-06-06 | 2010-12-09 | Carol Baltazar | Hot/cold temperature treatment apparatus |
-
2013
- 2013-11-15 AU AU2013344545A patent/AU2013344545A1/en not_active Abandoned
- 2013-11-15 CA CA2890215A patent/CA2890215A1/en not_active Abandoned
- 2013-11-15 WO PCT/US2013/070251 patent/WO2014078630A1/en not_active Ceased
- 2013-11-15 EP EP13854814.4A patent/EP2919843A4/en not_active Withdrawn
- 2013-11-15 JP JP2015542806A patent/JP2016501074A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014078630A1 (en) | 2014-05-22 |
| EP2919843A4 (en) | 2016-08-03 |
| EP2919843A1 (en) | 2015-09-23 |
| JP2016501074A (ja) | 2016-01-18 |
| AU2013344545A1 (en) | 2015-05-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20150238725A1 (en) | Non-invasive brain temperature regulating devices for enhancing sleep | |
| US20220280748A1 (en) | Non-invasive brain temperature regulating devices for enhancing sleep | |
| CA2649875C (en) | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders | |
| CA2890215A1 (en) | Non-invasive brain temperature regulating devices for enhancing sleep | |
| US10610661B2 (en) | Noninvasive, regional brain thermal stimuli for the treatment of migraine | |
| US9492313B2 (en) | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders | |
| US20170319815A1 (en) | Method and apparatuses for modulating sleep by chemical activation of temperature receptors | |
| US20170252534A1 (en) | Forehead cooling method and device to stimulate the parasympathetic nervous system for the treatment of insomnia | |
| JP2019523028A (ja) | テザーレス着用可能温度デバイス及び睡眠障害及び神経障害の治療のためにそれらを使用する方法 | |
| JP2017505657A (ja) | Ａｂｒｅｕ脳トンネルでモニタして治療を提供するデバイス | |
| US20230046024A1 (en) | Noninvasive, Regional Brain Thermal Stimuli for the Treatment of Neurological Disorders | |
| US12290640B2 (en) | Noninvasive, regional brain thermal stimulation for inducing relaxation | |
| AU2017268269A1 (en) | Forehead cooling method and device to stimulate the parasympathetic nervous system for the treatment of insomnia | |
| US20250256057A1 (en) | Noninvasive, Regional Brain Thermal Stimulation for Inducing Relaxation | |
| AU2007240754B2 (en) | Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders | |
| HK1230056A1 (en) | Devices to monitor and provide treatment at an abreu brain tunnel |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20181115 |