CA2889372C - Adaptateurs pour dispositif d'analyse directe d'echantillons et leurs procedes d'utilisation - Google Patents
Adaptateurs pour dispositif d'analyse directe d'echantillons et leurs procedes d'utilisation Download PDFInfo
- Publication number
- CA2889372C CA2889372C CA2889372A CA2889372A CA2889372C CA 2889372 C CA2889372 C CA 2889372C CA 2889372 A CA2889372 A CA 2889372A CA 2889372 A CA2889372 A CA 2889372A CA 2889372 C CA2889372 C CA 2889372C
- Authority
- CA
- Canada
- Prior art keywords
- sleeve
- capillary
- adapter
- mass spectrometer
- internal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000004458 analytical method Methods 0.000 title claims abstract description 117
- 238000000034 method Methods 0.000 title claims description 43
- 230000008878 coupling Effects 0.000 claims abstract description 110
- 238000010168 coupling process Methods 0.000 claims abstract description 110
- 238000005859 coupling reaction Methods 0.000 claims abstract description 110
- 239000012212 insulator Substances 0.000 claims abstract description 65
- 239000000463 material Substances 0.000 description 27
- 150000002500 ions Chemical class 0.000 description 26
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 12
- 229910010293 ceramic material Inorganic materials 0.000 description 11
- 229920000642 polymer Polymers 0.000 description 10
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 7
- 239000000919 ceramic Substances 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 239000012811 non-conductive material Substances 0.000 description 6
- 125000006850 spacer group Chemical group 0.000 description 6
- 229910001220 stainless steel Inorganic materials 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 239000010935 stainless steel Substances 0.000 description 5
- RUDFQVOCFDJEEF-UHFFFAOYSA-N yttrium(III) oxide Inorganic materials [O-2].[O-2].[O-2].[Y+3].[Y+3] RUDFQVOCFDJEEF-UHFFFAOYSA-N 0.000 description 5
- 238000003795 desorption Methods 0.000 description 4
- 230000000977 initiatory effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 229920001169 thermoplastic Polymers 0.000 description 4
- 239000004416 thermosoftening plastic Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- -1 but not limited to Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000011068 loading method Methods 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 238000000065 atmospheric pressure chemical ionisation Methods 0.000 description 2
- 238000000451 chemical ionisation Methods 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 238000000132 electrospray ionisation Methods 0.000 description 2
- 238000010265 fast atom bombardment Methods 0.000 description 2
- 238000009616 inductively coupled plasma Methods 0.000 description 2
- 239000011810 insulating material Substances 0.000 description 2
- 238000005040 ion trap Methods 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 238000001004 secondary ion mass spectrometry Methods 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 238000004252 FT/ICR mass spectrometry Methods 0.000 description 1
- 239000004696 Poly ether ether ketone Substances 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013375 chromatographic separation Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 229910001026 inconel Inorganic materials 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920006260 polyaryletherketone Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920002530 polyetherether ketone Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000011819 refractory material Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0404—Capillaries used for transferring samples or ions
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/041—Controlled or regulated
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Certains modes de réalisation de l'invention concernent des adaptateurs destinés à être utilisés pour accoupler un dispositif d'analyse directe d'échantillons avec un instrument d'analyse tel qu'un spectromètre de masse par exemple. Dans certains exemples, l'adaptateur peut comprendre un système d'accouplement interne séparé d'un système d'accouplement externe par l'intermédiaire d'un isolant.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/662,500 US9412572B2 (en) | 2012-10-28 | 2012-10-28 | Sample holders and methods of using them |
US13/662,500 | 2012-10-28 | ||
US13/662,801 US9733156B2 (en) | 2012-10-29 | 2012-10-29 | Sample platforms and methods of using them |
US13/662,745 US9117641B2 (en) | 2012-10-29 | 2012-10-29 | Direct sample analysis device adapters and methods of using them |
US13/662,745 | 2012-10-29 | ||
US13/662,801 | 2012-10-29 | ||
PCT/US2013/066993 WO2014066872A2 (fr) | 2012-10-28 | 2013-10-27 | Adaptateurs pour dispositif d'analyse directe d'échantillons et leurs procédés d'utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2889372A1 CA2889372A1 (fr) | 2014-05-01 |
CA2889372C true CA2889372C (fr) | 2022-12-06 |
Family
ID=50545376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2889372A Active CA2889372C (fr) | 2012-10-28 | 2013-10-27 | Adaptateurs pour dispositif d'analyse directe d'echantillons et leurs procedes d'utilisation |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2912677B1 (fr) |
CN (1) | CN205582883U (fr) |
CA (1) | CA2889372C (fr) |
WO (1) | WO2014066872A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9590583B2 (en) * | 2015-06-29 | 2017-03-07 | Agilent Technologies, Inc. | Alternating current (AC) coupler for wideband AC signals and related methods |
CN106769280B (zh) * | 2016-11-24 | 2019-10-29 | 中国石油大学(华东) | 一种简易海洋沉积物古地磁研究分样装置 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5157260A (en) * | 1991-05-17 | 1992-10-20 | Finnian Corporation | Method and apparatus for focusing ions in viscous flow jet expansion region of an electrospray apparatus |
US5965883A (en) * | 1997-08-25 | 1999-10-12 | California Institute Of Technology | Capillary for electrospray ion source |
US6248999B1 (en) * | 1998-09-24 | 2001-06-19 | Finnigan Corporation | Assembly for coupling an ion source to a mass analyzer |
US6794644B2 (en) | 2000-02-18 | 2004-09-21 | Melvin A. Park | Method and apparatus for automating an atmospheric pressure ionization (API) source for mass spectrometry |
US6657191B2 (en) * | 2001-03-02 | 2003-12-02 | Bruker Daltonics Inc. | Means and method for multiplexing sprays in an electrospray ionization source |
US7274015B2 (en) * | 2001-08-08 | 2007-09-25 | Sionex Corporation | Capacitive discharge plasma ion source |
US6707039B1 (en) * | 2002-09-19 | 2004-03-16 | Agilent Technologies, Inc. | AP-MALDI target illumination device and method for using an AP-MALDI target illumination device |
US7030373B2 (en) * | 2003-12-19 | 2006-04-18 | Applera Corporation | MALDI plate construction with grid |
JP4356491B2 (ja) * | 2004-03-26 | 2009-11-04 | 株式会社島津製作所 | ガスクロマトグラフ質量分析装置 |
US20060054805A1 (en) * | 2004-09-13 | 2006-03-16 | Flanagan Michael J | Multi-inlet sampling device for mass spectrometer ion source |
US7262841B2 (en) * | 2005-03-17 | 2007-08-28 | Agilent Technologies, Inc. | Laser alignment for ion source |
FR2886871B1 (fr) * | 2005-06-09 | 2008-10-17 | Centre Nat Rech Scient | Nebuliseur a debit nanometrique d'un effluent liquide et installation de nebulisation comportant un tel nebuliseur |
US7598488B2 (en) * | 2006-09-20 | 2009-10-06 | Park Melvin A | Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry |
EP2160235B1 (fr) * | 2007-06-01 | 2016-11-30 | Purdue Research Foundation | Interface de pression atmosphérique discontinue |
US8415619B2 (en) * | 2009-11-13 | 2013-04-09 | University of Glascgow | Methods and systems for mass spectrometry |
KR20110071320A (ko) * | 2009-12-21 | 2011-06-29 | 한국기초과학지원연구원 | 이온 주입기, 이를 포함하는 질량 분석기 및 이를 이용한 이온 집속 방법 |
-
2013
- 2013-10-27 EP EP13849385.3A patent/EP2912677B1/fr active Active
- 2013-10-27 CA CA2889372A patent/CA2889372C/fr active Active
- 2013-10-27 WO PCT/US2013/066993 patent/WO2014066872A2/fr active Application Filing
- 2013-10-27 CN CN201390001015.9U patent/CN205582883U/zh not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2889372A1 (fr) | 2014-05-01 |
EP2912677B1 (fr) | 2021-04-07 |
EP2912677A4 (fr) | 2016-08-10 |
WO2014066872A2 (fr) | 2014-05-01 |
CN205582883U (zh) | 2016-09-14 |
WO2014066872A3 (fr) | 2014-06-19 |
EP2912677A2 (fr) | 2015-09-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20181022 |
|
EEER | Examination request |
Effective date: 20181022 |
|
EEER | Examination request |
Effective date: 20181022 |
|
EEER | Examination request |
Effective date: 20181022 |