CA2889029A1 - Triazine derivatives for the treatment of conditions associated with nicotinamide adenine dinucleotide phosphate oxidase - Google Patents
Triazine derivatives for the treatment of conditions associated with nicotinamide adenine dinucleotide phosphate oxidase Download PDFInfo
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- CA2889029A1 CA2889029A1 CA2889029A CA2889029A CA2889029A1 CA 2889029 A1 CA2889029 A1 CA 2889029A1 CA 2889029 A CA2889029 A CA 2889029A CA 2889029 A CA2889029 A CA 2889029A CA 2889029 A1 CA2889029 A1 CA 2889029A1
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- Prior art keywords
- alkyl
- halogen
- triazine
- diamine
- methyl
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
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- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
- C07D251/18—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom with nitrogen atoms directly attached to the two other ring carbon atoms, e.g. guanamines
Landscapes
- Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261717803P | 2012-10-24 | 2012-10-24 | |
| EP12189823 | 2012-10-24 | ||
| EP12189823.3 | 2012-10-24 | ||
| US61/717,803 | 2012-10-24 | ||
| PCT/EP2013/072098 WO2014064118A1 (en) | 2012-10-24 | 2013-10-22 | Triazine derivatives for the treatment of conditions associated with nicotinamide adenine dinucleotide phosphate oxidase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2889029A1 true CA2889029A1 (en) | 2014-05-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2889029A Abandoned CA2889029A1 (en) | 2012-10-24 | 2013-10-22 | Triazine derivatives for the treatment of conditions associated with nicotinamide adenine dinucleotide phosphate oxidase |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9687490B2 (enExample) |
| EP (1) | EP2911667B1 (enExample) |
| JP (1) | JP2015535225A (enExample) |
| CN (1) | CN104918616A (enExample) |
| CA (1) | CA2889029A1 (enExample) |
| IN (1) | IN2015DN03761A (enExample) |
| WO (1) | WO2014064118A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10195167B2 (en) | 2014-12-16 | 2019-02-05 | Glucox Biotech Ab | Compounds for use in the treatment of conditions associated with NADPH oxidase |
| JP2018505226A (ja) * | 2015-02-16 | 2018-02-22 | グルコックス・バイオテック・アーベー | N2−(3,4−ジメチルフェニル)−6−((4−(p−トリル)ピペラジン−1−イル)メチル)−1,3,5−トリアジン−2,4−ジアミン |
| CN110325516A (zh) | 2016-12-29 | 2019-10-11 | 米尼奥尔克斯治疗有限公司 | 杂芳基化合物和它们的用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2709784A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| EP2166009A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as nadph oxidase inhibitors |
| EP2166008A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2165707A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2166010A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2305679A1 (en) | 2009-09-28 | 2011-04-06 | GenKyoTex SA | Pyrazoline dione derivatives as nadph oxidase inhibitors |
| EP2361911A1 (en) | 2010-02-18 | 2011-08-31 | GenKyoTex SA | Pyrazolo piperidine derivatives as NADPH oxidase inhibitors |
| EP2361912A1 (en) | 2010-02-18 | 2011-08-31 | GenKyoTex SA | Pyrazolo piperidine derivatives as NADPH oxidase inhibitors |
| CN102389430B (zh) * | 2011-09-07 | 2013-08-28 | 苏州大学 | 一种小分子化合物在制备抗肺癌药物中的应用 |
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2013
- 2013-10-22 WO PCT/EP2013/072098 patent/WO2014064118A1/en not_active Ceased
- 2013-10-22 JP JP2015538418A patent/JP2015535225A/ja active Pending
- 2013-10-22 CA CA2889029A patent/CA2889029A1/en not_active Abandoned
- 2013-10-22 EP EP13789502.5A patent/EP2911667B1/en not_active Not-in-force
- 2013-10-22 IN IN3761DEN2015 patent/IN2015DN03761A/en unknown
- 2013-10-22 US US14/437,678 patent/US9687490B2/en not_active Expired - Fee Related
- 2013-10-22 CN CN201380055721.6A patent/CN104918616A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN104918616A (zh) | 2015-09-16 |
| IN2015DN03761A (enExample) | 2015-10-02 |
| JP2015535225A (ja) | 2015-12-10 |
| US9687490B2 (en) | 2017-06-27 |
| WO2014064118A1 (en) | 2014-05-01 |
| EP2911667A1 (en) | 2015-09-02 |
| US20150283146A1 (en) | 2015-10-08 |
| EP2911667B1 (en) | 2017-02-22 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20191022 |