CA2886757C - Traitement d'anxiete avec l'antagoniste il1.alpha. - Google Patents

Traitement d'anxiete avec l'antagoniste il1.alpha. Download PDF

Info

Publication number
CA2886757C
CA2886757C CA2886757A CA2886757A CA2886757C CA 2886757 C CA2886757 C CA 2886757C CA 2886757 A CA2886757 A CA 2886757A CA 2886757 A CA2886757 A CA 2886757A CA 2886757 C CA2886757 C CA 2886757C
Authority
CA
Canada
Prior art keywords
antibody
monoclonal antibody
human
pharmaceutical composition
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2886757A
Other languages
English (en)
Other versions
CA2886757A1 (fr
Inventor
John Simard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of CA2886757A1 publication Critical patent/CA2886757A1/fr
Application granted granted Critical
Publication of CA2886757C publication Critical patent/CA2886757C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Le nombre de lésions d'acné chez un sujet humain est réduit par administration au sujet d'une composition pharmaceutique qui comprend un véhicule pharmaceutiquement acceptable et une quantité thérapeutiquement efficace d'un agent qui lie sélectivement IL-1a. L'anxiété et d'autres affections psychiatriques sont également améliorées par ce traitement.
CA2886757A 2012-10-04 2013-10-01 Traitement d'anxiete avec l'antagoniste il1.alpha. Active CA2886757C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261709741P 2012-10-04 2012-10-04
US61/709,741 2012-10-04
PCT/US2013/062899 WO2014055541A1 (fr) 2012-10-04 2013-10-01 Traitement d'affections psychiatriques

Publications (2)

Publication Number Publication Date
CA2886757A1 CA2886757A1 (fr) 2014-04-10
CA2886757C true CA2886757C (fr) 2022-04-05

Family

ID=50435375

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2886757A Active CA2886757C (fr) 2012-10-04 2013-10-01 Traitement d'anxiete avec l'antagoniste il1.alpha.

Country Status (7)

Country Link
EP (1) EP2903643A4 (fr)
JP (3) JP6750941B2 (fr)
KR (1) KR20150064091A (fr)
CN (1) CN104684581A (fr)
AU (1) AU2013327498B2 (fr)
CA (1) CA2886757C (fr)
WO (1) WO2014055541A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130098279A (ko) 2010-06-18 2013-09-04 엑스바이오테크, 인크. 관절염 치료
KR20210128021A (ko) 2010-08-23 2021-10-25 얀센 바이오테크 인코포레이티드 종양성 질병들에 대한 치료
US9724409B2 (en) 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
US9809649B2 (en) 2011-09-23 2017-11-07 Xbiotech, Inc. Cachexia treatment
US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
KR20190117579A (ko) 2017-02-16 2019-10-16 엑스바이오테크, 인크. 화농성 한선염의 치료

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405021D0 (en) * 1994-03-15 1994-04-27 Unilever Plc Skin treatment composition
US5455234A (en) * 1994-03-16 1995-10-03 Ahluwalia; Gurpreet S. Inhibition of hair growth
JP2002226457A (ja) * 2001-02-02 2002-08-14 Ajinomoto Co Inc 新規シスチン誘導体及び炎症因子活性化抑制剤
RU2498998C2 (ru) * 2008-05-30 2013-11-20 ИксБиотеч, Инк. АНТИТЕЛА К ИНТЕРЛЕЙКИНУ-1α И СПОСОБЫ ПРИМЕНЕНИЯ
EP2391652A4 (fr) * 2009-01-29 2013-01-02 Abbott Lab Protéines de liaison à il-1
US9724409B2 (en) * 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
DK2694107T3 (en) * 2011-04-01 2018-12-10 Xbiotech Inc TREATMENT OF DERMATOLOGICAL DISORDERS

Also Published As

Publication number Publication date
CA2886757A1 (fr) 2014-04-10
AU2013327498A1 (en) 2015-04-02
JP2020143133A (ja) 2020-09-10
KR20150064091A (ko) 2015-06-10
CN104684581A (zh) 2015-06-03
JP2022177132A (ja) 2022-11-30
JP2015531396A (ja) 2015-11-02
AU2013327498B2 (en) 2018-06-28
WO2014055541A1 (fr) 2014-04-10
JP6750941B2 (ja) 2020-09-02
EP2903643A1 (fr) 2015-08-12
EP2903643A4 (fr) 2016-06-15

Similar Documents

Publication Publication Date Title
US11191831B2 (en) Treatment of psychiatric conditions
AU2017201201B2 (en) Treatment for dermatological pathologies
US11390672B2 (en) Arthritis treatment
CA2886757C (fr) Traitement d'anxiete avec l'antagoniste il1.alpha.

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180928