CA2886757C - Traitement d'anxiete avec l'antagoniste il1.alpha. - Google Patents
Traitement d'anxiete avec l'antagoniste il1.alpha. Download PDFInfo
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- CA2886757C CA2886757C CA2886757A CA2886757A CA2886757C CA 2886757 C CA2886757 C CA 2886757C CA 2886757 A CA2886757 A CA 2886757A CA 2886757 A CA2886757 A CA 2886757A CA 2886757 C CA2886757 C CA 2886757C
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- 230000003248 secreting effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
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- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
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- 241000894007 species Species 0.000 description 1
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- 239000003381 stabilizer Substances 0.000 description 1
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- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- NRUKOCRGYNPUPR-QBPJDGROSA-N teniposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@@H](OC[C@H]4O3)C=3SC=CC=3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 NRUKOCRGYNPUPR-QBPJDGROSA-N 0.000 description 1
- 229960001278 teniposide Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940044693 topoisomerase inhibitor Drugs 0.000 description 1
- 230000014723 transformation of host cell by virus Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- 239000002452 tumor necrosis factor alpha inhibitor Substances 0.000 description 1
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- 239000013598 vector Substances 0.000 description 1
- 229960003048 vinblastine Drugs 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Le nombre de lésions d'acné chez un sujet humain est réduit par administration au sujet d'une composition pharmaceutique qui comprend un véhicule pharmaceutiquement acceptable et une quantité thérapeutiquement efficace d'un agent qui lie sélectivement IL-1a. L'anxiété et d'autres affections psychiatriques sont également améliorées par ce traitement.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261709741P | 2012-10-04 | 2012-10-04 | |
US61/709,741 | 2012-10-04 | ||
PCT/US2013/062899 WO2014055541A1 (fr) | 2012-10-04 | 2013-10-01 | Traitement d'affections psychiatriques |
Publications (2)
Publication Number | Publication Date |
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CA2886757A1 CA2886757A1 (fr) | 2014-04-10 |
CA2886757C true CA2886757C (fr) | 2022-04-05 |
Family
ID=50435375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2886757A Active CA2886757C (fr) | 2012-10-04 | 2013-10-01 | Traitement d'anxiete avec l'antagoniste il1.alpha. |
Country Status (7)
Country | Link |
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EP (1) | EP2903643A4 (fr) |
JP (3) | JP6750941B2 (fr) |
KR (1) | KR20150064091A (fr) |
CN (1) | CN104684581A (fr) |
AU (1) | AU2013327498B2 (fr) |
CA (1) | CA2886757C (fr) |
WO (1) | WO2014055541A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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KR20130098279A (ko) | 2010-06-18 | 2013-09-04 | 엑스바이오테크, 인크. | 관절염 치료 |
KR20210128021A (ko) | 2010-08-23 | 2021-10-25 | 얀센 바이오테크 인코포레이티드 | 종양성 질병들에 대한 치료 |
US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
US9809649B2 (en) | 2011-09-23 | 2017-11-07 | Xbiotech, Inc. | Cachexia treatment |
US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
KR20190117579A (ko) | 2017-02-16 | 2019-10-16 | 엑스바이오테크, 인크. | 화농성 한선염의 치료 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9405021D0 (en) * | 1994-03-15 | 1994-04-27 | Unilever Plc | Skin treatment composition |
US5455234A (en) * | 1994-03-16 | 1995-10-03 | Ahluwalia; Gurpreet S. | Inhibition of hair growth |
JP2002226457A (ja) * | 2001-02-02 | 2002-08-14 | Ajinomoto Co Inc | 新規シスチン誘導体及び炎症因子活性化抑制剤 |
RU2498998C2 (ru) * | 2008-05-30 | 2013-11-20 | ИксБиотеч, Инк. | АНТИТЕЛА К ИНТЕРЛЕЙКИНУ-1α И СПОСОБЫ ПРИМЕНЕНИЯ |
EP2391652A4 (fr) * | 2009-01-29 | 2013-01-02 | Abbott Lab | Protéines de liaison à il-1 |
US9724409B2 (en) * | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
DK2694107T3 (en) * | 2011-04-01 | 2018-12-10 | Xbiotech Inc | TREATMENT OF DERMATOLOGICAL DISORDERS |
-
2013
- 2013-10-01 CA CA2886757A patent/CA2886757C/fr active Active
- 2013-10-01 AU AU2013327498A patent/AU2013327498B2/en not_active Ceased
- 2013-10-01 JP JP2015535741A patent/JP6750941B2/ja active Active
- 2013-10-01 EP EP13843079.8A patent/EP2903643A4/fr not_active Withdrawn
- 2013-10-01 WO PCT/US2013/062899 patent/WO2014055541A1/fr active Application Filing
- 2013-10-01 CN CN201380050428.0A patent/CN104684581A/zh active Pending
- 2013-10-01 KR KR1020157009988A patent/KR20150064091A/ko not_active IP Right Cessation
-
2020
- 2020-05-25 JP JP2020090717A patent/JP2020143133A/ja active Pending
-
2022
- 2022-09-12 JP JP2022144756A patent/JP2022177132A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2886757A1 (fr) | 2014-04-10 |
AU2013327498A1 (en) | 2015-04-02 |
JP2020143133A (ja) | 2020-09-10 |
KR20150064091A (ko) | 2015-06-10 |
CN104684581A (zh) | 2015-06-03 |
JP2022177132A (ja) | 2022-11-30 |
JP2015531396A (ja) | 2015-11-02 |
AU2013327498B2 (en) | 2018-06-28 |
WO2014055541A1 (fr) | 2014-04-10 |
JP6750941B2 (ja) | 2020-09-02 |
EP2903643A1 (fr) | 2015-08-12 |
EP2903643A4 (fr) | 2016-06-15 |
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CA2886757C (fr) | Traitement d'anxiete avec l'antagoniste il1.alpha. |
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EEER | Examination request |
Effective date: 20180928 |