CA2874979A1 - Antigen binding proteins that bind dll-4 - Google Patents
Antigen binding proteins that bind dll-4 Download PDFInfo
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- CA2874979A1 CA2874979A1 CA2874979A CA2874979A CA2874979A1 CA 2874979 A1 CA2874979 A1 CA 2874979A1 CA 2874979 A CA2874979 A CA 2874979A CA 2874979 A CA2874979 A CA 2874979A CA 2874979 A1 CA2874979 A1 CA 2874979A1
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- dll
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261654019P | 2012-05-31 | 2012-05-31 | |
| US61/654,019 | 2012-05-31 | ||
| PCT/US2013/042912 WO2014062245A2 (en) | 2012-05-31 | 2013-05-28 | Antigen binding proteins that bind dll-4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2874979A1 true CA2874979A1 (en) | 2014-04-24 |
Family
ID=49670535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2874979A Abandoned CA2874979A1 (en) | 2012-05-31 | 2013-05-28 | Antigen binding proteins that bind dll-4 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10174107B2 (OSRAM) |
| EP (1) | EP2855523A4 (OSRAM) |
| JP (1) | JP2015520172A (OSRAM) |
| CN (1) | CN104603151A (OSRAM) |
| CA (1) | CA2874979A1 (OSRAM) |
| HK (1) | HK1206038A1 (OSRAM) |
| WO (1) | WO2014062245A2 (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201818814T4 (tr) | 2009-10-16 | 2019-01-21 | Oncomed Pharm Inc | Dll4 antagonist antikorlarının ve anti-hipertansif ajanların terapötik kombinasyonu ve kullanımı. |
| PT3485903T (pt) | 2011-09-23 | 2023-02-17 | Mereo Biopharma 5 Inc | Agentes de ligação a vegf/dll4 e utilizações dos mesmos |
| JP2015520172A (ja) | 2012-05-31 | 2015-07-16 | ソレント・セラピューティクス・インコーポレイテッドＳｏｒｒｅｎｔｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｄｌｌ−４に結合する抗原結合蛋白質 |
| BR112017000130A2 (pt) | 2014-07-11 | 2018-01-09 | Genentech Inc | método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer |
| ES2808153T3 (es) | 2014-10-31 | 2021-02-25 | Mereo Biopharma 5 Inc | Terapia de combinación para tratamiento de enfermedad |
| CA2993177A1 (en) * | 2015-07-22 | 2017-01-26 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind lag3 |
| AU2016326609B2 (en) | 2015-09-23 | 2023-03-09 | Mereo Biopharma 5, Inc. | Methods and compositions for treatment of cancer |
| KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060088905A (ko) * | 2000-06-16 | 2006-08-07 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 면역특이적으로 ＢＬｙＳ에 결합하는 항체 |
| IL149820A0 (en) | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
| US20070244709A1 (en) * | 2006-04-17 | 2007-10-18 | Earthworks Systems, Llc | Methods of producing and recycling plastic cards |
| CL2007001623A1 (es) | 2006-06-06 | 2008-01-18 | Genentech Inc | Anticuerpo anti-dll4; polinucleotido que lo codifica; vector y celula huesped que comprenden dicho polinucleotido; metodo para elaborar el anticuerpo e inmunojugado; metodo de deteccion de dll4 y metodo diagnostico de un trastorno asociado a dll4; composicion que comprende al anticuerpo. |
| SI2066694T1 (sl) | 2006-09-29 | 2016-02-29 | Oncomed Pharmaceuticals, Inc. | Sestavki in postopki za diagnosticiranje in zdravljenje raka |
| NO347649B1 (no) * | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| CA2735900A1 (en) | 2008-09-19 | 2010-03-25 | Medimmune, Llc | Antibodies directed to dll4 and uses thereof |
| CA2771575A1 (en) * | 2009-08-29 | 2011-03-03 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| JP2015520172A (ja) | 2012-05-31 | 2015-07-16 | ソレント・セラピューティクス・インコーポレイテッドＳｏｒｒｅｎｔｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｄｌｌ−４に結合する抗原結合蛋白質 |
-
2013
- 2013-05-28 JP JP2015515116A patent/JP2015520172A/ja active Pending
- 2013-05-28 HK HK15106562.8A patent/HK1206038A1/xx unknown
- 2013-05-28 EP EP13847493.7A patent/EP2855523A4/en not_active Withdrawn
- 2013-05-28 US US13/903,793 patent/US10174107B2/en active Active
- 2013-05-28 CA CA2874979A patent/CA2874979A1/en not_active Abandoned
- 2013-05-28 CN CN201380028998.XA patent/CN104603151A/zh active Pending
- 2013-05-28 WO PCT/US2013/042912 patent/WO2014062245A2/en not_active Ceased
-
2019
- 2019-01-07 US US16/241,828 patent/US10717779B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014062245A3 (en) | 2014-10-09 |
| CN104603151A (zh) | 2015-05-06 |
| US10717779B2 (en) | 2020-07-21 |
| WO2014062245A2 (en) | 2014-04-24 |
| US10174107B2 (en) | 2019-01-08 |
| JP2015520172A (ja) | 2015-07-16 |
| US20130323248A1 (en) | 2013-12-05 |
| US20190169282A1 (en) | 2019-06-06 |
| EP2855523A4 (en) | 2016-02-17 |
| EP2855523A2 (en) | 2015-04-08 |
| HK1206038A1 (en) | 2015-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20190528 |