CA2872338C - Drug delivery system and methods of treating open angle glaucoma and ocular hypertension - Google Patents
Drug delivery system and methods of treating open angle glaucoma and ocular hypertension Download PDFInfo
- Publication number
- CA2872338C CA2872338C CA2872338A CA2872338A CA2872338C CA 2872338 C CA2872338 C CA 2872338C CA 2872338 A CA2872338 A CA 2872338A CA 2872338 A CA2872338 A CA 2872338A CA 2872338 C CA2872338 C CA 2872338C
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- Prior art keywords
- lacrimal implant
- implant
- eye
- lacrimal
- latanoprost
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- 230000002792 vascular Effects 0.000 description 1
- 230000009723 vascular congestion Effects 0.000 description 1
- 239000005526 vasoconstrictor agent Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- 230000004382 visual function Effects 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
- 229940100445 wheat starch Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Prostheses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261642287P | 2012-05-03 | 2012-05-03 | |
| US61/642,287 | 2012-05-03 | ||
| US201261644401P | 2012-05-08 | 2012-05-08 | |
| US201261644397P | 2012-05-08 | 2012-05-08 | |
| US61/644,401 | 2012-05-08 | ||
| US61/644,397 | 2012-05-08 | ||
| US201261659921P | 2012-06-14 | 2012-06-14 | |
| US61/659,921 | 2012-06-14 | ||
| US201261680641P | 2012-08-07 | 2012-08-07 | |
| US61/680,641 | 2012-08-07 | ||
| US201261717615P | 2012-10-23 | 2012-10-23 | |
| US61/717,615 | 2012-10-23 | ||
| PCT/IB2013/000694 WO2013164671A1 (en) | 2012-05-03 | 2013-02-27 | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2872338A1 CA2872338A1 (en) | 2013-11-07 |
| CA2872338C true CA2872338C (en) | 2021-09-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2872338A Active CA2872338C (en) | 2012-05-03 | 2013-02-27 | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP2844224B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6213560B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN105473130A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2872338C (cg-RX-API-DMAC7.html) |
| HK (1) | HK1222810A1 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2014DN09713A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013164671A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012021107A2 (en) | 2010-08-12 | 2012-02-16 | Nanyang Technological University | A liposomal formulation for ocular drug delivery |
| US9956195B2 (en) | 2014-01-07 | 2018-05-01 | Nanyang Technological University | Stable liposomal formulations for ocular drug delivery |
| GB201714392D0 (en) * | 2017-09-07 | 2017-10-25 | Marsteller Laurence | Methods and devices for treating glaucoma |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3321108A (en) | 1965-11-26 | 1967-05-23 | William E Bowe | Printing ink dispenser |
| US3681608A (en) | 1971-03-17 | 1972-08-01 | Us Navy | Laser beam receiver having a high signal to noise ratio |
| US4281654A (en) | 1980-04-07 | 1981-08-04 | Alza Corporation | Drug delivery system for controlled ocular therapy |
| US4952581A (en) | 1987-04-03 | 1990-08-28 | The Trustees Of Columbia University In The City Of New York | Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure |
| US4936008A (en) | 1988-05-09 | 1990-06-26 | Teledyne Mec | Laser striping method for assembling TWT |
| US4934708A (en) | 1988-05-20 | 1990-06-19 | Kolkind Gerald L | Family quiz board game |
| US5296504A (en) | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US5259508A (en) | 1992-08-27 | 1993-11-09 | Beckerman Stephen M | Protective shipping package |
| ES2105333T3 (es) | 1992-10-13 | 1997-10-16 | Alcon Lab Inc | Combinaciones de prostaglandinas y derivados de clonidina para el tratamiento del glaucoma. |
| US6622308B1 (en) | 1999-03-23 | 2003-09-16 | Scientific-Atlanta, Inc. | Automatic digital television (DTV) bypass for a CATV converter using a CATV tuner |
| US6534693B2 (en) | 2000-11-06 | 2003-03-18 | Afmedica, Inc. | Surgically implanted devices having reduced scar tissue formation |
| US7300364B2 (en) | 2004-02-06 | 2007-11-27 | Acushnet Company | Multi-layer golf ball having velocity gradient from faster center to slower cover |
| WO2004075781A2 (en) | 2003-02-26 | 2004-09-10 | Medivas, Llc | Bioactive stents and methods for use thereof |
| JP4104137B2 (ja) * | 2003-05-30 | 2008-06-18 | 有限会社エム・エル・シー | 涙点プラグ |
| US7662864B2 (en) | 2003-06-04 | 2010-02-16 | Rutgers, The State University Of New Jersey | Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent |
| US20050129731A1 (en) | 2003-11-03 | 2005-06-16 | Roland Horres | Biocompatible, biostable coating of medical surfaces |
| EP3643702A1 (en) | 2004-01-05 | 2020-04-29 | Nicox S.A. | Prostaglandin derivatives |
| US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| US7922702B2 (en) | 2004-07-02 | 2011-04-12 | Qlt Inc. | Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such a delivery device |
| CA2648066C (en) | 2006-03-31 | 2012-07-03 | Forsight Labs, Llc | Drug delivery methods, structures, and compositions for nasolacrimal system |
| KR20090102810A (ko) * | 2006-12-26 | 2009-09-30 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 시력 결함을 억제하기 위한 약물 전달 임플란트 |
| UY30883A1 (es) | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
| MX2010002617A (es) | 2007-09-07 | 2010-06-01 | Qlt Plug Delivery Inc | Implantes lagrimales y metodos relacionados. |
| KR20100067099A (ko) | 2007-09-07 | 2010-06-18 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 눈물 임플랜트 검출 |
| CN101969897A (zh) | 2007-09-07 | 2011-02-09 | Qlt栓塞输送公司 | 用于泪腺植入物的插入和抽出工具 |
| SG184738A1 (en) | 2007-09-07 | 2012-10-30 | Quadra Logic Tech Inc | Drug cores for sustained release of therapeutic agents |
| WO2009137085A2 (en) | 2008-05-09 | 2009-11-12 | Qlt Plug Delivery, Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
| SG173069A1 (en) | 2009-01-23 | 2011-08-29 | Quadra Logic Tech Inc | Sustained released delivery of one or more agents |
| SG174133A1 (en) * | 2009-02-23 | 2011-10-28 | Quadra Logic Tech Inc | Lacrimal implants and related methods |
| US20120245539A1 (en) | 2009-11-27 | 2012-09-27 | Qlt Inc. | Lacrimal implants including split and insertable drug core |
-
2013
- 2013-02-27 WO PCT/IB2013/000694 patent/WO2013164671A1/en not_active Ceased
- 2013-02-27 EP EP13784720.8A patent/EP2844224B1/en active Active
- 2013-02-27 JP JP2015509510A patent/JP6213560B2/ja active Active
- 2013-02-27 CN CN201380035719.2A patent/CN105473130A/zh active Pending
- 2013-02-27 CA CA2872338A patent/CA2872338C/en active Active
- 2013-02-27 HK HK16111148.0A patent/HK1222810A1/zh unknown
-
2014
- 2014-11-18 IN IN9713DEN2014 patent/IN2014DN09713A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014DN09713A (cg-RX-API-DMAC7.html) | 2015-07-31 |
| JP6213560B2 (ja) | 2017-10-18 |
| HK1222810A1 (zh) | 2017-07-14 |
| EP2844224A1 (en) | 2015-03-11 |
| EP2844224A4 (en) | 2016-02-24 |
| JP2015520628A (ja) | 2015-07-23 |
| CA2872338A1 (en) | 2013-11-07 |
| EP2844224B1 (en) | 2018-04-11 |
| CN105473130A (zh) | 2016-04-06 |
| WO2013164671A1 (en) | 2013-11-07 |
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| US9974685B2 (en) | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension | |
| CA2872338C (en) | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension | |
| HK1158951A (en) | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180227 |