CA2854424A1 - Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands - Google Patents

Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands Download PDF

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Publication number
CA2854424A1
CA2854424A1 CA2854424A CA2854424A CA2854424A1 CA 2854424 A1 CA2854424 A1 CA 2854424A1 CA 2854424 A CA2854424 A CA 2854424A CA 2854424 A CA2854424 A CA 2854424A CA 2854424 A1 CA2854424 A1 CA 2854424A1
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Canada
Prior art keywords
methyl
phenyl
fluoro
pyrazol
methylsulfonyl
Prior art date
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Abandoned
Application number
CA2854424A
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English (en)
French (fr)
Inventor
Robert Frank-Foltyn
Thomas Christoph
Nils Damann
Bernhard Lesch
Gregor Bahrenberg
Derek John Saunders
Hannelore Stockhausen
Yong-Soo Kim
Myeong-Seop Kim
Jeewoo Lee
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Grünenthal GmbH
Original Assignee
Grünenthal GmbH
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Filing date
Publication date
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Publication of CA2854424A1 publication Critical patent/CA2854424A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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CA2854424A 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands Abandoned CA2854424A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11008927 2011-11-09
EP11008927.3 2011-11-09
PCT/EP2012/072143 WO2013068464A1 (en) 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
CA2854424A1 true CA2854424A1 (en) 2013-05-16

Family

ID=47143914

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2854424A Abandoned CA2854424A1 (en) 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands

Country Status (13)

Country Link
EP (1) EP2776401A1 (enExample)
JP (1) JP2014532744A (enExample)
KR (1) KR20140091041A (enExample)
CN (1) CN104066720A (enExample)
AR (1) AR088799A1 (enExample)
AU (1) AU2012334068A1 (enExample)
BR (1) BR112014011108A2 (enExample)
CA (1) CA2854424A1 (enExample)
HK (1) HK1202117A1 (enExample)
IN (1) IN2014KN00865A (enExample)
MX (1) MX2014005233A (enExample)
TW (1) TW201326135A (enExample)
WO (1) WO2013068464A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20221373T1 (hr) 2014-03-07 2023-01-06 Biocryst Pharmaceuticals, Inc. Supstituirani pirazoli kao inhibitori kalikreina u ljudskoj plazmi
ES2713700T3 (es) 2014-11-24 2019-05-23 Medifron Dbt Inc Derivados de carboxamida y urea a base de oxazol y tiazol sustituidos como ligandos del receptor de vainilloide II
CN114920697A (zh) * 2022-05-16 2022-08-19 河南应用技术职业学院 杂环基取代的茚满丙酰胺类化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2427436T3 (pl) 2009-05-07 2013-06-28 Gruenenthal Gmbh Podstawione aromatyczne pochodne karboksamidu i mocznika jako ligandy receptora waniloidowego
RU2553392C2 (ru) * 2009-05-07 2015-06-10 Грюненталь Гмбх Замещенные фенилмочевины и фениламиды в качестве лигандов ваниллоидных рецепторов

Also Published As

Publication number Publication date
TW201326135A (zh) 2013-07-01
EP2776401A1 (en) 2014-09-17
CN104066720A (zh) 2014-09-24
KR20140091041A (ko) 2014-07-18
JP2014532744A (ja) 2014-12-08
IN2014KN00865A (enExample) 2015-10-02
AR088799A1 (es) 2014-07-10
BR112014011108A2 (pt) 2017-05-16
WO2013068464A1 (en) 2013-05-16
AU2012334068A1 (en) 2014-05-22
MX2014005233A (es) 2014-08-22
HK1202117A1 (en) 2015-09-18

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Effective date: 20171108