CA2848516C - Detection of isotype profiles as signatures for disease - Google Patents

Detection of isotype profiles as signatures for disease Download PDF

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Publication number
CA2848516C
CA2848516C CA2848516A CA2848516A CA2848516C CA 2848516 C CA2848516 C CA 2848516C CA 2848516 A CA2848516 A CA 2848516A CA 2848516 A CA2848516 A CA 2848516A CA 2848516 C CA2848516 C CA 2848516C
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CA
Canada
Prior art keywords
detection
signatures
disease
isotype profiles
biological sample
Prior art date
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Active
Application number
CA2848516A
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English (en)
French (fr)
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CA2848516A1 (en
Inventor
Maria U. Hutchins
Daniel Seligson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lineage Biosciences Inc Canada
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Lineage Biosciences Inc Canada
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Publication of CA2848516A1 publication Critical patent/CA2848516A1/en
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Publication of CA2848516C publication Critical patent/CA2848516C/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2848516A 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease Active CA2848516C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161537878P 2011-09-22 2011-09-22
US61/537,878 2011-09-22
PCT/US2012/056911 WO2013044234A1 (en) 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease

Publications (2)

Publication Number Publication Date
CA2848516A1 CA2848516A1 (en) 2013-03-28
CA2848516C true CA2848516C (en) 2021-06-15

Family

ID=47080791

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2848516A Active CA2848516C (en) 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease

Country Status (7)

Country Link
US (1) US20130078633A1 (https=)
EP (1) EP2758550B1 (https=)
JP (2) JP6198736B2 (https=)
CN (1) CN104271759B (https=)
AU (1) AU2012312028A1 (https=)
CA (1) CA2848516C (https=)
WO (1) WO2013044234A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2525568B (en) 2013-03-15 2020-10-14 Abvitro Llc Single cell barcoding for antibody discovery
EP3611262B1 (en) 2013-03-15 2020-11-11 Lineage Biosciences, Inc. Methods of sequencing the immune repertoire
US11203783B2 (en) 2013-11-21 2021-12-21 Repertoire Genesis Incorporation T cell receptor and B cell receptor repertoire analysis system, and use of same in treatment and diagnosis
US10941446B2 (en) 2014-03-12 2021-03-09 Icahn School Of Medicine At Mount Sinai Method for identifying kidney allograft recipients at risk for chronic injury
CN113444783B (zh) 2014-06-26 2024-04-09 西奈山伊坎医学院 通过分析预示性基因集诊断亚临床和临床的急性排异的方法
EP3950944A1 (en) 2014-09-15 2022-02-09 AbVitro LLC High-throughput nucleotide library sequencing
CN105040111B (zh) * 2015-05-28 2017-07-14 眭维国 系统性红斑狼疮图谱模型的构建方法
GB201612242D0 (en) * 2016-07-14 2016-08-31 Genome Res Ltd And Cambridge Entpr Ltd Novel kit
CN107179288A (zh) * 2017-07-03 2017-09-19 中国人民解放军第三军医大学 一种唾液中分泌型免疫球蛋白的检测方法
CA3095198A1 (en) 2018-04-16 2019-10-24 Icahn School Of Medicine At Mount Sinai Method and kits for prediction of acute rejection and renal allograft loss using pre-transplant transcriptomic signatures in recipient blood
CN110400600A (zh) * 2019-08-01 2019-11-01 枣庄学院 一种基于旋转森林算法的miRNA-疾病相关性预测方法
EP4093887A1 (en) * 2020-01-22 2022-11-30 Life Technologies Corporation Immune repertoire biomarkers in autoimmune disease and immunodeficiency disorders
CN112485304B (zh) * 2020-12-14 2022-08-09 河北工业大学 一种基于电导法的牛奶检测方法及系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5018067A (en) 1987-01-12 1991-05-21 Iameter Incorporated Apparatus and method for improved estimation of health resource consumption through use of diagnostic and/or procedure grouping and severity of illness indicators
US20020038227A1 (en) 2000-02-25 2002-03-28 Fey Christopher T. Method for centralized health data management
US20040122296A1 (en) 2002-12-18 2004-06-24 John Hatlestad Advanced patient management for triaging health-related data
US7468032B2 (en) 2002-12-18 2008-12-23 Cardiac Pacemakers, Inc. Advanced patient management for identifying, displaying and assisting with correlating health-related data
CA2544708A1 (en) * 2003-11-03 2005-05-12 Genenews, Inc. Liver cancer biomarkers
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
EP2364368B1 (en) 2008-11-07 2014-01-15 Sequenta, Inc. Methods of monitoring conditions by sequence analysis
CN102918163B (zh) * 2009-09-08 2016-10-05 美国控股实验室公司 用于诊断自闭症谱系障碍的组合物和方法

Also Published As

Publication number Publication date
AU2012312028A1 (en) 2014-04-10
US20130078633A1 (en) 2013-03-28
WO2013044234A1 (en) 2013-03-28
CN104271759A (zh) 2015-01-07
CN104271759B (zh) 2018-01-16
EP2758550A1 (en) 2014-07-30
JP2018007689A (ja) 2018-01-18
AU2012312028A8 (en) 2014-04-24
JP2014527831A (ja) 2014-10-23
JP6198736B2 (ja) 2017-09-20
EP2758550B1 (en) 2016-10-26
CA2848516A1 (en) 2013-03-28

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