CA2848516C - Detection of isotype profiles as signatures for disease - Google Patents

Detection of isotype profiles as signatures for disease Download PDF

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Publication number
CA2848516C
CA2848516C CA2848516A CA2848516A CA2848516C CA 2848516 C CA2848516 C CA 2848516C CA 2848516 A CA2848516 A CA 2848516A CA 2848516 A CA2848516 A CA 2848516A CA 2848516 C CA2848516 C CA 2848516C
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CA
Canada
Prior art keywords
detection
signatures
disease
isotype profiles
biological sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2848516A
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English (en)
French (fr)
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CA2848516A1 (en
Inventor
Maria U. Hutchins
Daniel Seligson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lineage Biosciences Inc Canada
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Lineage Biosciences Inc Canada
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Publication date
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Publication of CA2848516A1 publication Critical patent/CA2848516A1/en
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Publication of CA2848516C publication Critical patent/CA2848516C/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2848516A 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease Active CA2848516C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161537878P 2011-09-22 2011-09-22
US61/537,878 2011-09-22
PCT/US2012/056911 WO2013044234A1 (en) 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease

Publications (2)

Publication Number Publication Date
CA2848516A1 CA2848516A1 (en) 2013-03-28
CA2848516C true CA2848516C (en) 2021-06-15

Family

ID=47080791

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2848516A Active CA2848516C (en) 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease

Country Status (7)

Country Link
US (1) US20130078633A1 (cg-RX-API-DMAC7.html)
EP (1) EP2758550B1 (cg-RX-API-DMAC7.html)
JP (2) JP6198736B2 (cg-RX-API-DMAC7.html)
CN (1) CN104271759B (cg-RX-API-DMAC7.html)
AU (1) AU2012312028A1 (cg-RX-API-DMAC7.html)
CA (1) CA2848516C (cg-RX-API-DMAC7.html)
WO (1) WO2013044234A1 (cg-RX-API-DMAC7.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3415626B1 (en) 2013-03-15 2020-01-22 Lineage Biosciences, Inc. Methods and compositions for tagging and analyzing samples
WO2014144495A1 (en) 2013-03-15 2014-09-18 Abvitro, Inc. Single cell bar-coding for antibody discovery
WO2015075939A1 (ja) 2013-11-21 2015-05-28 Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 Ｔ細胞受容体およびｂ細胞受容体レパトアの解析システムならびにその治療および診断への利用
US10941446B2 (en) 2014-03-12 2021-03-09 Icahn School Of Medicine At Mount Sinai Method for identifying kidney allograft recipients at risk for chronic injury
CN113444783B (zh) 2014-06-26 2024-04-09 西奈山伊坎医学院 通过分析预示性基因集诊断亚临床和临床的急性排异的方法
SG10201911069WA (en) 2014-09-15 2020-01-30 Abvitro Llc High-throughput nucleotide library sequencing
CN105040111B (zh) * 2015-05-28 2017-07-14 眭维国 系统性红斑狼疮图谱模型的构建方法
GB201612242D0 (en) * 2016-07-14 2016-08-31 Genome Res Ltd And Cambridge Entpr Ltd Novel kit
CN107179288A (zh) * 2017-07-03 2017-09-19 中国人民解放军第三军医大学 一种唾液中分泌型免疫球蛋白的检测方法
WO2019204267A1 (en) 2018-04-16 2019-10-24 Icahn School Of Medicine At Mount Sinai Method and kits for prediction of acute rejection and renal allograft loss using pre-transplant transcriptomic signatures in recipient blood
CN110400600A (zh) * 2019-08-01 2019-11-01 枣庄学院 一种基于旋转森林算法的miRNA-疾病相关性预测方法
EP4093887A1 (en) * 2020-01-22 2022-11-30 Life Technologies Corporation Immune repertoire biomarkers in autoimmune disease and immunodeficiency disorders
CN112485304B (zh) * 2020-12-14 2022-08-09 河北工业大学 一种基于电导法的牛奶检测方法及系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5018067A (en) 1987-01-12 1991-05-21 Iameter Incorporated Apparatus and method for improved estimation of health resource consumption through use of diagnostic and/or procedure grouping and severity of illness indicators
US20020038227A1 (en) 2000-02-25 2002-03-28 Fey Christopher T. Method for centralized health data management
US7468032B2 (en) 2002-12-18 2008-12-23 Cardiac Pacemakers, Inc. Advanced patient management for identifying, displaying and assisting with correlating health-related data
US20040122296A1 (en) 2002-12-18 2004-06-24 John Hatlestad Advanced patient management for triaging health-related data
CN101039951A (zh) * 2003-11-03 2007-09-19 基因信息公司 肝癌生物标志物
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
GB2483810B (en) * 2008-11-07 2012-09-05 Sequenta Inc Methods for correlating clonotypes with diseases in a population
EP3135772B1 (en) * 2009-09-08 2019-10-23 Laboratory Corporation of America Holdings Method for diagnosing autism spectrum disorders

Also Published As

Publication number Publication date
JP6198736B2 (ja) 2017-09-20
CA2848516A1 (en) 2013-03-28
WO2013044234A1 (en) 2013-03-28
CN104271759B (zh) 2018-01-16
JP2018007689A (ja) 2018-01-18
CN104271759A (zh) 2015-01-07
AU2012312028A8 (en) 2014-04-24
EP2758550B1 (en) 2016-10-26
EP2758550A1 (en) 2014-07-30
US20130078633A1 (en) 2013-03-28
JP2014527831A (ja) 2014-10-23
AU2012312028A1 (en) 2014-04-10

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Effective date: 20170922