CA2848471C - Modified gram positive bacteria and uses thereof - Google Patents
Modified gram positive bacteria and uses thereof Download PDFInfo
- Publication number
- CA2848471C CA2848471C CA2848471A CA2848471A CA2848471C CA 2848471 C CA2848471 C CA 2848471C CA 2848471 A CA2848471 A CA 2848471A CA 2848471 A CA2848471 A CA 2848471A CA 2848471 C CA2848471 C CA 2848471C
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- gram
- positive bacterium
- trehalose
- bacterium according
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
- A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
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- A23K—FODDER
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- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- C12Y—ENZYMES
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Communicable Diseases (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3131722A CA3131722A1 (en) | 2011-09-23 | 2012-09-21 | Modified gram positive bacteria and uses thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11182643 | 2011-09-23 | ||
| EP11182643.4 | 2011-09-23 | ||
| PCT/EP2012/068634 WO2013041673A1 (en) | 2011-09-23 | 2012-09-21 | Modified gram positive bacteria and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3131722A Division CA3131722A1 (en) | 2011-09-23 | 2012-09-21 | Modified gram positive bacteria and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2848471A1 CA2848471A1 (en) | 2013-03-28 |
| CA2848471C true CA2848471C (en) | 2021-11-16 |
Family
ID=47040665
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2848471A Active CA2848471C (en) | 2011-09-23 | 2012-09-21 | Modified gram positive bacteria and uses thereof |
| CA3131722A Abandoned CA3131722A1 (en) | 2011-09-23 | 2012-09-21 | Modified gram positive bacteria and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3131722A Abandoned CA3131722A1 (en) | 2011-09-23 | 2012-09-21 | Modified gram positive bacteria and uses thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9347036B2 (https=) |
| EP (2) | EP3382006B1 (https=) |
| JP (2) | JP6329903B2 (https=) |
| KR (1) | KR102028771B1 (https=) |
| CN (1) | CN103917639B (https=) |
| AU (2) | AU2012311479B2 (https=) |
| BR (1) | BR112014006883A8 (https=) |
| CA (2) | CA2848471C (https=) |
| DK (1) | DK2758513T3 (https=) |
| ES (1) | ES2676270T3 (https=) |
| HU (1) | HUE038336T2 (https=) |
| RU (1) | RU2653757C2 (https=) |
| WO (1) | WO2013041673A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3382006B1 (en) | 2011-09-23 | 2021-02-17 | Intrexon Actobiotics NV | Modified gram positive bacteria and uses thereof |
| WO2013041672A1 (en) | 2011-09-23 | 2013-03-28 | Actogenix Nv | Modified gram positive bacteria and uses thereof |
| EP3237622B1 (en) | 2014-12-23 | 2021-02-24 | Ilya Pharma AB | Methods for wound healing |
| CA3011331C (en) | 2016-01-14 | 2025-05-13 | Intrexon Actobiotics N.V. | Compositions and methods for the treatment of type 1 diabetes |
| JP7016865B2 (ja) | 2016-09-02 | 2022-03-03 | イントレクソン・アクトバイオテイクス・エヌブイ | Il-10およびインスリンを安定的に発現する遺伝子改変された細菌 |
| CN109983028B (zh) * | 2016-09-13 | 2023-10-20 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 黏膜黏附性微生物 |
| IT201600122724A1 (it) * | 2016-12-02 | 2018-06-02 | Sofar Spa | Exopolysaccharides and uses thereof |
| CN113347983A (zh) * | 2018-10-09 | 2021-09-03 | 第二基因组股份有限公司 | 用于递送有效治疗上皮屏障功能障碍的蛋白质的乳酸乳球菌表达系统 |
| CN114854807B (zh) * | 2022-05-23 | 2024-05-17 | 中国科学院微生物研究所 | 一种生产海藻糖六磷酸的方法 |
| CN121204013A (zh) * | 2025-11-04 | 2025-12-26 | 大连理工大学 | 一种海藻糖-6-磷酸磷酸化酶及其突变体与应用 |
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| AU770726B2 (en) | 1998-10-20 | 2004-02-26 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Use of a cytokine-producing lactococcus strain to treat colitis |
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| WO2002090551A2 (en) | 2001-05-03 | 2002-11-14 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Self-containing lactococcus strain |
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| EP1720974B2 (en) | 2004-02-24 | 2021-12-22 | Chr. Hansen A/S | Frozen lactic acid bacteria culture of individual pellets |
| AU2005243441A1 (en) | 2004-05-18 | 2005-11-24 | Universiteit Gent | Self-containing lactobacillus strain |
| ES2439698T3 (es) * | 2004-08-20 | 2014-01-24 | Actogenix N.V. | Procedimiento para mejorar la conservación de lactococos |
| WO2007025977A2 (en) | 2005-08-30 | 2007-03-08 | Actogenix Nv | Anti-tnf alpha producing lactic acid bacteria for the treatment of chronic enterocolitis |
| AU2006319216B2 (en) | 2005-11-29 | 2012-09-13 | Intrexon Actobiotics Nv | Induction of mucosal tolerance to antigens |
| RU2008147398A (ru) | 2006-05-02 | 2010-06-10 | Актогеникс Н.В. (Be) | Доставка пептидов, связанных с ожирением, через кишечник посредством микроорганизмов |
| JP2010513245A (ja) | 2006-12-14 | 2010-04-30 | アクトジェニックス・エヌブイ | 免疫調節を誘起するための結合分子の送達 |
| EP2115146B1 (en) | 2007-01-12 | 2016-07-06 | Intrexon Actobiotics NV | Lactococcus promoters and uses thereof |
| CN103933563B (zh) | 2007-01-25 | 2016-09-28 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 使用遗传修饰的乳杆菌通过抗原的粘膜递送治疗免疫疾病 |
| DK3181682T3 (da) | 2008-09-29 | 2021-07-05 | Intrexon Actobiotics Nv | Reduceret kolonisering af mikrober på slimhinden |
| RU2393214C1 (ru) * | 2009-01-29 | 2010-06-27 | Общество с ограниченной ответственностью "ИнноПроб"(ООО"ИнноПроб") | Иммунобиологическое противоаллергическое средство (варианты), штамм lactobacillus acidophilus nkjc, штамм lactobacillus acidophilus jch, штамм lactobacillus acidophilus kaa |
| WO2010124855A1 (en) | 2009-04-30 | 2010-11-04 | Actogenix Nv | Cryoprotectants for freeze drying of lactic acid bacteria |
| EP3382006B1 (en) * | 2011-09-23 | 2021-02-17 | Intrexon Actobiotics NV | Modified gram positive bacteria and uses thereof |
| WO2013041672A1 (en) * | 2011-09-23 | 2013-03-28 | Actogenix Nv | Modified gram positive bacteria and uses thereof |
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