CA2847611A1 - Tamper resistant pharmaceutical formulations - Google Patents
Tamper resistant pharmaceutical formulations Download PDFInfo
- Publication number
- CA2847611A1 CA2847611A1 CA2847611A CA2847611A CA2847611A1 CA 2847611 A1 CA2847611 A1 CA 2847611A1 CA 2847611 A CA2847611 A CA 2847611A CA 2847611 A CA2847611 A CA 2847611A CA 2847611 A1 CA2847611 A1 CA 2847611A1
- Authority
- CA
- Canada
- Prior art keywords
- dosage form
- oral dosage
- active agent
- particles
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535743P | 2011-09-16 | 2011-09-16 | |
| US61/535,743 | 2011-09-16 | ||
| PCT/IB2012/001914 WO2013038267A1 (en) | 2011-09-16 | 2012-09-14 | Tamper resistant pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2847611A1 true CA2847611A1 (en) | 2013-03-21 |
Family
ID=47018275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2847611A Abandoned CA2847611A1 (en) | 2011-09-16 | 2012-09-14 | Tamper resistant pharmaceutical formulations |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20140341984A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2755640B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6110384B2 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2012310250B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2847611A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2641437T3 (cg-RX-API-DMAC10.html) |
| IL (1) | IL231485A (cg-RX-API-DMAC10.html) |
| MX (1) | MX355478B (cg-RX-API-DMAC10.html) |
| WO (1) | WO2013038267A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2003024429A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Polymer release system |
| US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
| US8877241B2 (en) | 2003-03-26 | 2014-11-04 | Egalet Ltd. | Morphine controlled release system |
| US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
| US8821928B2 (en) | 2007-06-04 | 2014-09-02 | Egalet Ltd. | Controlled release pharmaceutical compositions for prolonged effect |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| AU2010265213B2 (en) | 2009-06-24 | 2012-08-23 | Egalet Ltd. | Controlled release formulations |
| TW201722406A (zh) * | 2012-03-02 | 2017-07-01 | 羅德製藥公司 | 抗破壞性立即釋出型調製劑類 |
| LT2838512T (lt) * | 2012-04-18 | 2018-11-12 | GrĆ¼nenthal GmbH | Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma |
| JP2015521988A (ja) | 2012-07-06 | 2015-08-03 | イガレット・リミテッド | 制御放出用乱用防止性医薬組成物 |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
| US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CA3075292A1 (en) * | 2017-10-20 | 2019-04-25 | Purdue Pharma L.P. | Pharmaceutical dosage forms |
| US12161754B2 (en) | 2017-12-20 | 2024-12-10 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK150008C (da) * | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
| US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| IL160217A0 (en) * | 2001-08-06 | 2004-07-25 | Euro Celtique Sa | Compositions and methods to prevent abuse of opioids |
| US20030068375A1 (en) * | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| DE10336400A1 (de) * | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| BRPI0415557A (pt) * | 2003-10-31 | 2006-12-26 | Hexal Ag | formulação contendo ingrediente ativo farmacêutico com revestimento |
| TWI365880B (en) | 2004-03-30 | 2012-06-11 | Euro Celtique Sa | Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp |
| US20060177380A1 (en) * | 2004-11-24 | 2006-08-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
| US20080152595A1 (en) * | 2004-11-24 | 2008-06-26 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
| KR100905511B1 (ko) * | 2005-01-28 | 2009-07-01 | 유로-셀띠끄 소시에떼 아노님 | 알코올 저항성 제형 |
| US20090022798A1 (en) * | 2007-07-20 | 2009-01-22 | Abbott Gmbh & Co. Kg | Formulations of nonopioid and confined opioid analgesics |
| US9023400B2 (en) * | 2006-05-24 | 2015-05-05 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| PL2079446T3 (pl) * | 2007-08-21 | 2012-04-30 | Teva Pharma | Preparat paliperidonu o przedłużonym uwalnianiu |
| GB0909680D0 (en) * | 2009-06-05 | 2009-07-22 | Euro Celtique Sa | Dosage form |
| PL2826467T3 (pl) * | 2010-12-22 | 2018-01-31 | Purdue Pharma Lp | Zamknięte, zabezpieczone przed manipulowaniem formy dozowania o kontrolowanym uwalnianiu |
-
2012
- 2012-09-14 US US14/344,279 patent/US20140341984A1/en not_active Abandoned
- 2012-09-14 AU AU2012310250A patent/AU2012310250B2/en active Active
- 2012-09-14 ES ES12813950.8T patent/ES2641437T3/es active Active
- 2012-09-14 JP JP2014530331A patent/JP6110384B2/ja active Active
- 2012-09-14 EP EP12813950.8A patent/EP2755640B1/en active Active
- 2012-09-14 WO PCT/IB2012/001914 patent/WO2013038267A1/en not_active Ceased
- 2012-09-14 MX MX2014003186A patent/MX355478B/es active IP Right Grant
- 2012-09-14 CA CA2847611A patent/CA2847611A1/en not_active Abandoned
-
2014
- 2014-03-12 IL IL231485A patent/IL231485A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013038267A1 (en) | 2013-03-21 |
| US20140341984A1 (en) | 2014-11-20 |
| JP2014526497A (ja) | 2014-10-06 |
| EP2755640B1 (en) | 2017-07-26 |
| EP2755640A1 (en) | 2014-07-23 |
| IL231485A0 (en) | 2014-04-30 |
| IL231485A (en) | 2017-03-30 |
| MX2014003186A (es) | 2015-10-12 |
| AU2012310250B2 (en) | 2016-03-03 |
| AU2012310250A1 (en) | 2013-05-02 |
| MX355478B (es) | 2018-04-19 |
| JP6110384B2 (ja) | 2017-04-05 |
| ES2641437T3 (es) | 2017-11-10 |
| WO2013038267A8 (en) | 2014-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170907 |
|
| FZDE | Discontinued |
Effective date: 20201218 |